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D-Index & Metrics

Biology and Biochemistry

D-Index
68
Citations
18858
World Ranking
7715
National Ranking
141

Overview

Florian M. Wurm is affiliated with the École Polytechnique Fédérale de Lausanne in Switzerland. Their research primarily focuses on the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with contributions spanning infectious diseases, molecular biology, and related subfields.

The scientist has published extensively on topics related to SARS-CoV-2 and COVID-19 research, viral infectious diseases and gene expression in insects, monoclonal and polyclonal antibody research, bacteriophages and microbial interactions, CAR-T cell therapy research, animal virus infections studies, and protein purification and stability.

Frequent publication venues include bioRxiv (Cold Spring Harbor Laboratory), Processes, npj Vaccines, Biochemistry, and Biotechnology Journal.

Among the recent papers authored or co-authored by Florian M. Wurm are:

  • "Site-Specific Steric Control of SARS-CoV-2 Spike Glycosylation," 2021, Biochemistry
  • "Naming CHO cells for bio-manufacturing: Genome plasticity and variant phenotypes of cell populations in bioreactors question the relevance of old names," 2021, Biotechnology Journal
  • "Trimeric SARS-CoV-2 Spike Proteins Produced from CHO Cells in Bioreactors Are High-Quality Antigens," 2020, Processes
  • "High-Titer Neutralizing Antibodies against the SARS-CoV-2 Delta Variant Induced by Alhydroxyquim-II-Adjuvanted Trimeric Spike Antigens," 2022, Microbiology Spectrum
  • "Dermal Delivery of a SARS-CoV-2 Subunit Vaccine Induces Immunogenicity against Variants of Concern," 2022, Vaccines

Frequent co-authors working with Florian M. Wurm include Paco Pino, Joeri Kint, Divor Kiseljak, James A. Triccas, and Tobias Welte.

Best Publications

  • Production of recombinant protein therapeutics in cultivated mammalian cells

    Florian M Wurm

  • Transfecting Mammalian Cells: Optimization of Critical Parameters Affecting Calcium-Phosphate Precipitate Formation

    Martin Jordan;Annette Schallhorn;Florian M. Wurm

  • Designing CD4 immunoadhesins for AIDS therapy

    Daniel J. Capon;Steven M. Chamow;Joyce Mordenti;Scot A. Marsters

  • Protection of chimpanzees from infection by HIV-1 after vaccination with recombinant glycoprotein gp120 but not gp160

    Berman Pw;Gregory Tj;Riddle L;Nakamura Gr

  • Recombinant protein production by large-scale transient gene expression in mammalian cells: state of the art and future perspectives.

    Lucia Baldi;David L. Hacker;Myriam Adam;Florian M. Wurm

  • Transfection of adherent and suspended cells by calcium phosphate

    Martin Jordan;Florian Wurm

  • Large-scale transient expression in mammalian cells for recombinant protein production.

    Florian Wurm;Alain Bernard

  • Biological properties of a CD4 immunoadhesin.

    Randal A. Byrn;Joyce Mordenti;Catherine Lucas;Douglas Smith

  • High resolution analysis of functional determinants on human tissue-type plasminogen activator

    W. F. Bennett;N. F. Paoni;B. A. Keyt;D. Botstein

  • Rational vector design and multi-pathway modulation of HEK 293E cells yield recombinant antibody titers exceeding 1 g/l by transient transfection under serum-free conditions

    Gaurav Backliwal;Markus Hildinger;Sebastien Chenuet;Sarah Wulhfard

  • Transient gene expression: recombinant protein production with suspension-adapted HEK293-EBNA cells

    Petra Meissner;Horst Pick;Alexandra Kulangara;Philippe Chatellard

  • GFP-expressing mammalian cells for fast, sensitive, noninvasive cell growth assessment in a kinetic mode.

    L. Hunt;M. Jordan;M. De Jesus;F. M. Wurm

  • CD8beta endows CD8 with efficient coreceptor function by coupling T cell receptor/CD3 to raft-associated CD8/p56(lck) complexes.

    Alexandre Arcaro;Claude Grégoire;Talitha R. Bakker;Lucia Baldi

  • Serum‐free large‐scale transient transfection of CHO cells

    Madiha Derouazi;Philippe Girard;Frédéric Van Tilborgh;Keyvan Iglesias

  • Inducible overproduction of the mouse c-myc protein in mammalian cells

    Florian M. Wurm;Katrina A. Gwinn;Robert E. Kingston

  • Lactate metabolism shift in CHO cell culture: the role of mitochondrial oxidative activity

    Francesca Zagari;Martin Jordan;Matthieu Stettler;Hervé Broly

  • Valproic acid: A viable alternative to sodium butyrate for enhancing protein expression in mammalian cell cultures

    Gaurav Backliwal;Markus Hildinger;Ivan Kuettel;Fanny Delegrange

  • TubeSpin satellites: a fast track approach for process development with animal cells using shaking technology

    Maria J De Jesus;Philippe Girard;Michaela Bourgeois;Gwendoline Baumgartner

  • Acrylic acid grafting and collagen immobilization on poly(ethylene terephthalate) surfaces for adherence and growth of human bladder smooth muscle cells

    Isabelle Bisson;Marek Kosinski;Sylvie Ruault;Bhuvanesh Gupta

  • Development of stable cell lines for production or regulated expression using matrix attachment regions

    Monique Zahn-Zabal;Michel Kobr;Pierre-Alain Girod;Markus Imhof

Frequent Co-Authors

Jöns Hilborn
Jöns Hilborn Uppsala University
Harm-Anton Klok
Harm-Anton Klok École Polytechnique Fédérale de Lausanne
Nicolas Mermod
Nicolas Mermod University of Lausanne
Alfio Quarteroni
Alfio Quarteroni Polytechnic University of Milan
Jeffrey A. Hubbell
Jeffrey A. Hubbell New York University
Bernard L. Schneider
Bernard L. Schneider École Polytechnique Fédérale de Lausanne
Immanuel F. Luescher
Immanuel F. Luescher University of Lausanne
Giampietro Corradin
Giampietro Corradin University of Lausanne
Nicole Déglon
Nicole Déglon University of Lausanne
Jacques S. Beckmann
Jacques S. Beckmann University of Lausanne

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