D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 57 Citations 15,052 184 World Ranking 6585 National Ranking 119

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Genetics

Florian M. Wurm spends much of his time researching Recombinant DNA, Cell culture, Molecular biology, Chinese hamster ovary cell and Transfection. His Recombinant DNA study incorporates themes from Plasminogen activator, Antibody, Gene expression and Binding site. His Cell culture research incorporates elements of Gene pool, Biophysics and Mutation rate.

Florian M. Wurm combines subjects such as CD3 Complex, Yeast, Cell biology, Protein folding and Green fluorescent protein with his study of Molecular biology. Florian M. Wurm has researched Chinese hamster ovary cell in several fields, including Cell growth, Regulation of gene expression, Gene, Chemically defined medium and Clone. His study on Transfection is covered under Biochemistry.

His most cited work include:

  • Production of recombinant protein therapeutics in cultivated mammalian cells (1661 citations)
  • Designing CD4 immunoadhesins for AIDS therapy (829 citations)
  • Transfecting Mammalian Cells: Optimization of Critical Parameters Affecting Calcium-Phosphate Precipitate Formation (761 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Molecular biology, Recombinant DNA, Transfection, Chinese hamster ovary cell and Cell culture. Florian M. Wurm usually deals with Molecular biology and limits it to topics linked to Transgene and Transposable element. His biological study spans a wide range of topics, including Biotechnology, Antibody and Gene expression.

In his study, which falls under the umbrella issue of Transfection, Biophysics is strongly linked to DNA. His research in Chinese hamster ovary cell intersects with topics in Reporter gene, Cell growth, Gene delivery and Cell biology. His Cell culture study frequently draws connections between adjacent fields such as Chromatography.

He most often published in these fields:

  • Molecular biology (40.14%)
  • Recombinant DNA (39.43%)
  • Transfection (36.20%)

What were the highlights of his more recent work (between 2012-2021)?

  • Chinese hamster ovary cell (35.48%)
  • Recombinant DNA (39.43%)
  • Cell culture (31.18%)

In recent papers he was focusing on the following fields of study:

Florian M. Wurm focuses on Chinese hamster ovary cell, Recombinant DNA, Cell culture, Transfection and Molecular biology. His work deals with themes such as Antibody, Gene, Transgene and Cell biology, which intersect with Chinese hamster ovary cell. His work carried out in the field of Recombinant DNA brings together such families of science as Biotechnology, Gene expression and Cell growth.

His Cell culture research incorporates themes from Carbohydrate metabolism and Mutation rate. His study focuses on the intersection of Transfection and fields such as HEK 293 cells with connections in the field of Genetic enhancement and Virology. Molecular biology is often connected to Methotrexate in his work.

Between 2012 and 2021, his most popular works were:

  • Lactate metabolism shift in CHO cell culture: the role of mitochondrial oxidative activity (125 citations)
  • CHO Quasispecies—Implications for Manufacturing Processes (101 citations)
  • DNA delivery with hyperbranched polylysine: a comparative study with linear and dendritic polylysine. (84 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Genetics

His primary areas of study are Cell culture, Chinese hamster ovary cell, Transfection, Recombinant DNA and Molecular biology. His study in Cell culture is interdisciplinary in nature, drawing from both Mass transfer coefficient, Chromatography and Suspension. His Chinese hamster ovary cell research is multidisciplinary, relying on both Carbohydrate metabolism, Metabolite, Membrane potential, Chemically defined medium and Mitochondrion.

To a larger extent, Florian M. Wurm studies Biochemistry with the aim of understanding Transfection. The various areas that Florian M. Wurm examines in his Recombinant DNA study include Cell, Gene expression and Transgene. He focuses mostly in the field of Gene expression, narrowing it down to matters related to HEK 293 cells and, in some cases, Structural biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Production of recombinant protein therapeutics in cultivated mammalian cells

Florian M Wurm.
Nature Biotechnology (2004)

2415 Citations

Transfecting Mammalian Cells: Optimization of Critical Parameters Affecting Calcium-Phosphate Precipitate Formation

Martin Jordan;Annette Schallhorn;Florian M. Wurm.
Nucleic Acids Research (1996)

994 Citations

Designing CD4 immunoadhesins for AIDS therapy

Daniel J. Capon;Steven M. Chamow;Joyce Mordenti;Scot A. Marsters.
Nature (1989)

870 Citations

Protection of chimpanzees from infection by HIV-1 after vaccination with recombinant glycoprotein gp120 but not gp160

P. W. Berman;T. J. Gregory;L. Riddle;G. R. Nakamura.
Nature (1990)

801 Citations

Recombinant protein production by large-scale transient gene expression in mammalian cells: state of the art and future perspectives.

Lucia Baldi;David L. Hacker;Myriam Adam;Florian M. Wurm.
Biotechnology Letters (2007)

325 Citations

Transfection of adherent and suspended cells by calcium phosphate

Martin Jordan;Florian Wurm.
Methods (2004)

301 Citations

Large-scale transient expression in mammalian cells for recombinant protein production.

Florian Wurm;Alain Bernard.
Current Opinion in Biotechnology (1999)

285 Citations

Biological properties of a CD4 immunoadhesin.

Randal A. Byrn;Joyce Mordenti;Catherine Lucas;Douglas Smith.
Nature (1990)

274 Citations

High resolution analysis of functional determinants on human tissue-type plasminogen activator

W. F. Bennett;N. F. Paoni;B. A. Keyt;D. Botstein.
Journal of Biological Chemistry (1991)

259 Citations

Transient gene expression: recombinant protein production with suspension-adapted HEK293-EBNA cells

Petra Meissner;Horst Pick;Alexandra Kulangara;Philippe Chatellard.
Biotechnology and Bioengineering (2001)

254 Citations

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