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Biology and Biochemistry

D-Index
43
Citations
6813
World Ranking
19406
National Ranking
77

Overview

Christoph Winkler is affiliated with the National University of Singapore in Singapore. Their research primarily focuses on biochemistry, genetics, and molecular biology, with substantial contributions in medicine. The scientist's work spans several subfields, including molecular biology, genetics, cell biology, oncology, and rheumatology.

Winkler's research topics encompass a diverse range of areas, notably bone metabolism and diseases, bone health and treatments, zebrafish biomedical research applications, genetic and clinical aspects of sex determination and chromosomal abnormalities, animal behavior and reproduction, neurogenetic and muscular disorders research, and bone health and osteoporosis research.

Frequent coauthors in their publications include Wen Hui Tan, Manfred Schartl, Ranran Liu, Quang Tien Phan, and Thorsten Wohland. Winkler has published frequently in venues such as bioRxiv (Cold Spring Harbor Laboratory), Human Molecular Genetics, Journal of Fish Biology, Frontiers in Cell and Developmental Biology, and Proceedings of the National Academy of Sciences.

Recent papers authored or coauthored by Christoph Winkler include:

  • Cxcl9l and Cxcr3.2 regulate recruitment of osteoclast progenitors to bone matrix in a medaka osteoporosis model (2020), Proceedings of the National Academy of Sciences
  • The Developmental and Genetic Architecture of the Sexually Selected Male Ornament of Swordtails (2020), Current Biology
  • A Neurexin2aa deficiency results in axon pathfinding defects and increased anxiety in zebrafish (2020), Human Molecular Genetics
  • The dietary anthocyanin delphinidin prevents bone resorption by inhibiting Rankl-induced differentiation of osteoclasts in a medaka (Oryzias latipes) model of osteoporosis (2020), Journal of Fish Biology
  • Multigenerational Impacts of Benzo(a)pyrene on Bone Modeling and Remodeling in Medaka (Oryzias latipes) (2020), Environmental Science & Technology

In addition to journal articles, Winkler has contributed to book publications, including the title "Fish as Model Organism for Skeletal Diseases" published by Frontiers Media in 2023.

Best Publications

  • A duplicated copy of DMRT1 in the sex-determining region of the Y chromosome of the medaka, Oryzias latipes

    Indrajit Nanda;Mariko Kondo;Ute Hornung;Shuichi Asakawa

  • Neurotrophin-6 is a new member of the nerve growth factor family.

    Rudolf Götz;Reinhard Köster;Christoph Winkler;Friedrich Raulf

  • Reduced U snRNP assembly causes motor axon degeneration in an animal model for spinal muscular atrophy

    Christoph Winkler;Christian Eggert;Dietmar Gradl;Gunter Meister

  • Pluripotency and differentiation of embryonic stem cell lines from the medakafish (Oryzias latipes)

    Yunhan Hong;Christoph Winkler;Manfred Schartl

  • Retinoic acid and Cyp26b1 are critical regulators of osteogenesis in the axial skeleton.

    Kirsten M. Spoorendonk;Josi Peterson-Maduro;Jörg Renn;Torsten Trowe

  • Production of medakafish chimeras from a stable embryonic stem cell line

    Yunhan Hong;Christoph Winkler;Manfred Schartl

  • A systematic genome-wide screen for mutations affecting organogenesis in Medaka, Oryzias latipes

    Makoto Furutani-Seiki;Takao Sasado;Chikako Morinaga;Hiroshi Suwa

  • The heterogeneous nuclear ribonucleoprotein-R is necessary for axonal β-actin mRNA translocation in spinal motor neurons

    Michael Glinka;Thomas Herrmann;Natalja Funk;Steven Havlicek

  • Developmentally regulated and non-sex-specific expression of autosomal dmrt genes in embryos of the Medaka fish (Oryzias latipes)

    Christoph Winkler;Ute Hornung;Mariko Kondo;Cordula Neuner

  • Pituitary-interrenal interaction in zebrafish interrenal organ development.

    Thuy Thanh To;Stefanie Hahner;Gabriela Nica;Klaus B. Rohr

  • Identification and comparative expression analysis of a second wt1 gene in zebrafish.

    Frank Bollig;Rebecca Mehringer;Birgit Perner;Christina Hartung

  • Rankl-induced osteoclastogenesis leads to loss of mineralization in a medaka osteoporosis model

    Thuy Thanh To;P. Eckhard Witten;Joerg Renn;Dipanjan Bhattacharya;Dipanjan Bhattacharya

  • Osterix-mCherry transgenic medaka for in vivo imaging of bone formation

    Joerg Renn;Christoph Winkler

  • Anaplastic Lymphoma Kinase Is Required for Neurogenesis in the Developing Central Nervous System of Zebrafish

    Sheng Yao;Mangeng Cheng;Qian Zhang;Mariusz Wasik

  • Small teleost fish provide new insights into human skeletal diseases.

    Paul Witten;MP Harris;Ann Huysseune;C Winkler

  • Functional divergence of two zebrafish midkine growth factors following fish-specific gene duplication.

    Christoph Winkler;Matthias Schäfer;Jutta Duschl;Manfred Schartl

  • Dynamic microtubules at the vegetal cortex predict the embryonic axis in zebrafish.

    Long Duc Tran;Hiromu Hino;Helen Quach;Shimin Lim;Shimin Lim

  • The midkine family of growth factors: diverse roles in nervous system formation and maintenance.

    C Winkler;S Yao

  • Transient expression of foreign DNA during embryonic and larval development of the medaka fish (Oryzias latipes).

    Christoph Winkler;Jürgen R. Vielkind;Manfred Schartl

  • SMN deficiency alters Nrxn2 expression and splicing in zebrafish and mouse models of spinal muscular atrophy

    Kelvin See;Preeti Yadav;Marieke Giegerich;Pearl S. Cheong

Frequent Co-Authors

Manfred Schartl
Manfred Schartl University of Würzburg
Jean-Nicolas Volff
Jean-Nicolas Volff École Normale Supérieure de Lyon
Joachim Wittbrodt
Joachim Wittbrodt Heidelberg University
Utz Fischer
Utz Fischer University of Würzburg
Bruno Allolio
Bruno Allolio University of Würzburg
Michael Sendtner
Michael Sendtner University of Würzburg
Judith Haendeler
Judith Haendeler Heinrich Heine University Düsseldorf
Akihiro Shima
Akihiro Shima University of Tokyo
Manfred Gessler
Manfred Gessler University of Würzburg
Makoto Furutani-Seiki
Makoto Furutani-Seiki Yamaguchi University

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