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D-Index & Metrics

Biology and Biochemistry

D-Index
77
Citations
21205
World Ranking
4784
National Ranking
354

Overview

Judith Haendeler is affiliated with Heinrich Heine University Düsseldorf in Germany. Their research spans the intersection of biochemistry, genetics, molecular biology, and medicine, with a focus across multiple subfields such as molecular biology, physiology, cardiology and cardiovascular medicine, immunology, and nutrition and dietetics.

The scientist's primary research topics include mitochondrial function and pathology, adipose tissue and metabolism, genetics, aging and longevity in model organisms, RNA and protein synthesis mechanisms, ATP synthase and ATPases research, heart rate variability and autonomic control, and telomeres, telomerase, and senescence.

Haendeler has contributed to numerous publications, with a total of 33 works in biochemistry, genetics, and molecular biology combined with 26 in medicine. Their frequent publication venues include Antioxidants (5 publications), Cells (4 publications), bioRxiv (Cold Spring Harbor Laboratory) (2 publications), Journal of Biological Chemistry (2 publications), and Circulation (1 publication).

Recent papers by Judith Haendeler include:

  • Protective Effects of Curcumin in Cardiovascular Diseases-Impact on Oxidative Stress and Mitochondria, 2022, Cells
  • Local Peroxynitrite Impairs Endothelial Transient Receptor Potential Vanilloid 4 Channels and Elevates Blood Pressure in Obesity, 2020, Circulation
  • Non-canonical functions of Telomerase Reverse Transcriptase - Impact on redox homeostasis, 2020, Redox Biology
  • The Aryl Hydrocarbon Receptor (AhR) in the Aging Process: Another Puzzling Role for This Highly Conserved Transcription Factor, 2020, Frontiers in Physiology
  • Telomerase as a Therapeutic Target in Cardiovascular Disease, 2021, Arteriosclerosis Thrombosis and Vascular Biology

Key collaborators in their research include Joachim Altschmied, with 24 joint publications; Philipp Jakobs with 12; Niloofar Ale-Agha with 10; Florian von Ameln with 6; and Fiona Cox with 5 coauthored papers.

Best Publications

  • Suppression of Apoptosis by Nitric Oxide via Inhibition of Interleukin-1β–converting Enzyme (ICE)-like and Cysteine Protease Protein (CPP)-32–like Proteases

    Stefanie Dimmeler;Judith Haendeler;Michael Nehls;Andreas M. Zeiher

  • SIRT1 controls endothelial angiogenic functions during vascular growth

    Michael Potente;Laleh Ghaeni;Danila Baldessari;Raul Mostoslavsky

  • Fluid Shear Stress Stimulates Phosphorylation of Akt in Human Endothelial Cells: Involvement in Suppression of Apoptosis

    Stefanie Dimmeler;Birgit Assmus;Corinna Hermann;Judith Haendeler

  • Nitric Oxide Inhibits Caspase-3 by S-Nitrosationin Vivo

    Lothar Rössig;Birgit Fichtlscherer;Kristin Breitschopf;Judith Haendeler

  • Oxidized Low-Density Lipoprotein Induces Apoptosis of Human Endothelial Cells by Activation of CPP32-Like Proteases A Mechanistic Clue to the ‘Response to Injury’ Hypothesis

    Stefanie Dimmeler;Judith Haendeler;Jan Galle;Andreas M. Zeiher

  • HMG-CoA Reductase Inhibitors Reduce Senescence and Increase Proliferation of Endothelial Progenitor Cells via Regulation of Cell Cycle Regulatory Genes

    Birgit Assmus;Carmen Urbich;Alexandra Aicher;Wolf K. Hofmann

  • Angiotensin II Induces Apoptosis of Human Endothelial Cells: Protective Effect of Nitric Oxide

    Stefanie Dimmeler;Volker Rippmann;Ulrike Weiland;Judith Haendeler

  • Aging Enhances the Sensitivity of Endothelial Cells Toward Apoptotic Stimuli: Important Role of Nitric Oxide

    Jörg Hoffmann;Judith Haendeler;Alexandra Aicher;Lothar Rössig

  • Cyclophilin A Is a Secreted Growth Factor Induced by Oxidative Stress

    Zheng-Gen Jin;Matthew G. Melaragno;Duan-Fang Liao;Chen Yan

  • Impaired CXCR4 Signaling Contributes to the Reduced Neovascularization Capacity of Endothelial Progenitor Cells From Patients With Coronary Artery Disease

    Dirk H. Walter;Judith Haendeler;Johannes Reinhold;Ulrich Rochwalsky

  • Redox regulatory and anti-apoptotic functions of thioredoxin depend on S-nitrosylation at cysteine 69

    Judith Haendeler;Jörg Hoffmann;Verena Tischler;Bradford C Berk

  • Shear stress inhibits apoptosis of human endothelial cells.

    Stefanie Dimmeler;Judith Haendeler;Volker Rippmann;Michael Nehls

  • Physical Exercise Prevents Cellular Senescence in Circulating Leukocytes and in the Vessel Wall

    Christian Werner;Tobias Fürster;Thomas Widmann;Janine Pöss

  • Dephosphorylation targets Bcl-2 for ubiquitin-dependent degradation: a link between the apoptosome and the proteasome pathway.

    Stefanie Dimmeler;Kristin Breitschopf;Judith Haendeler;Andreas M. Zeiher

  • Posttranslational modification of Bcl-2 facilitates its proteasome-dependent degradation: molecular characterization of the involved signaling pathway.

    Kristin Breitschopf;Judith Haendeler;Philipp Malchow;Andreas M. Zeiher

  • Antioxidants Inhibit Nuclear Export of Telomerase Reverse Transcriptase and Delay Replicative Senescence of Endothelial Cells

    Judith Haendeler;Jörg Hoffmann;J. Florian Diehl;Mariuca Vasa

  • Mitochondrial Telomerase Reverse Transcriptase Binds to and Protects Mitochondrial DNA and Function From Damage

    Judith Haendeler;Stefan Dröse;Nicole Büchner;Sascha Jakob

  • Cell-to-Cell Connection of Endothelial Progenitor Cells With Cardiac Myocytes by Nanotubes: A Novel Mechanism for Cell Fate Changes?

    Masamichi Koyanagi;Ralf P. Brandes;Judith Haendeler;Andreas M. Zeiher

  • Src and Cas Mediate JNK Activation but Not ERK1/2 and p38 Kinases by Reactive Oxygen Species

    Masanori Yoshizumi;Jun Ichi Abe;Judith Haendeler;Qunhua Huang

  • Hydrogen peroxide triggers nuclear export of telomerase reverse transcriptase via Src kinase family-dependent phosphorylation of tyrosine 707.

    Judith Haendeler;Jörg Hoffmann;Ralf P. Brandes;Andreas M. Zeiher

Frequent Co-Authors

Stefanie Dimmeler
Stefanie Dimmeler Goethe University Frankfurt
Andreas M. Zeiher
Andreas M. Zeiher Goethe University Frankfurt
Bradford C. Berk
Bradford C. Berk University of Rochester
Alexandra Aicher
Alexandra Aicher Goethe University Frankfurt
Ulrich Laufs
Ulrich Laufs Saarland University
Ralf P. Brandes
Ralf P. Brandes Goethe University Frankfurt
Ulrich Brandt
Ulrich Brandt Radboud University
Jean Krutmann
Jean Krutmann Heinrich Heine University Düsseldorf
Vicente Andrés
Vicente Andrés Spanish National Centre for Cardiovascular Research
Elisabetta Dejana
Elisabetta Dejana Uppsala University

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