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Molecular Biology

D-Index
66
Citations
14050
World Ranking
1625
National Ranking
114

Overview

Christoph Englert is affiliated with Friedrich Schiller University Jena in Germany. Their research spans several areas within the broader fields of Biochemistry, Genetics, and Molecular Biology, as well as Medicine.

They have contributed extensively to subfields such as Molecular Biology, Nature and Landscape Conservation, Genetics, Pulmonary and Respiratory Medicine, and Cell Biology.

Their main research topics include:

  • Renal and related cancers
  • Fish biology, ecology, and behavior
  • CRISPR and Genetic Engineering
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Congenital heart defects research
  • Retinal Development and Disorders
  • Neonatal Respiratory Health Research

Englert has published research articles in several frequently targeted journals, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Pathology
  • Aging Cell
  • Cold Spring Harbor Protocols
  • Chromosome Research

Some notable recent publications include:

  • Sex chromosome differentiation via changes in the Y chromosome repeat landscape in African annual killifishes Nothobranchius furzeri and N. kadleci, 2022, Chromosome Research
  • ADAM10 mediates ectopic proximal tubule development and renal fibrosis through Notch signalling, 2020, The Journal of Pathology
  • Generation of a transparent killifish line through multiplex CRISPR/Cas9-mediated gene inactivation, 2023, eLife
  • Systems Analysis Reveals Ageing-Related Perturbations in Retinoids and Sex Hormones in Alzheimer's and Parkinson's Diseases, 2021, Biomedicines
  • Aging Activates the Immune System and Alters the Regenerative Capacity in the Zebrafish Heart, 2022, Cells

Frequent co-authors collaborating with Englert include:

  • Johannes Krug
  • Annekatrin Richter
  • Hanna Reuter
  • Marco Groth
  • Birgit Perner

Englert's work integrates molecular techniques and genetic approaches to address questions in developmental biology, disease mechanisms, and regenerative biology, often using model organisms such as zebrafish and killifish. Their contributions reflect a diverse portfolio that bridges fundamental genetics with clinical and translational aspects.

Best Publications

  • INDUCTION OF GADD45 AND JNK/SAPK-DEPENDENT APOPTOSIS FOLLOWING INDUCIBLE EXPRESSION OF BRCA1

    D.Paul Harkin;James M Bean;David Miklos;Young-Han Song

  • Germ-line BRCA1 mutations in Jewish and non-Jewish women with early-onset breast cancer.

    Michael G. FitzGerald;Deborah J. MacDonald;Michael Krainer;Ingrid Hoover

  • Lymphotoxin β receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE−/− mice

    Rolf Gräbner;Katharina Lötzer;Sandra Döpping;Markus Hildner

  • Homozygous Inactivation of Sox9 Causes Complete XY Sex Reversal in Mice

    Francisco Barrionuevo;Stefan Bagheri-Fam;Jürgen Klattig;Ralf Kist;Ralf Kist

  • WT1 suppresses synthesis of the epidermal growth factor receptor and induces apoptosis.

    C. Englert;Xianyu Hou;Shyamala Maheswaran;P. Bennett

  • The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis.

    Shyamala Maheswaran;C. Englert;P. Bennett;G. Heinrich

  • A novel repressor, par-4, modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1.

    R W Johnstone;R H See;S F Sells;J Wang

  • The Wilms tumor genes wt1a and wt1b control different steps during formation of the zebrafish pronephros

    Birgit Perner;Christoph Englert;Christoph Englert;Frank Bollig

  • Characterization of Cell Lines Allowing Tightly Regulated Expression of Hepatitis C Virus Core Protein

    Darius Moradpour;Christoph Englert;Takaji Wakita;Jack R. Wands

  • Identification of adult nephron progenitors capable of kidney regeneration in zebrafish

    Cuong Q. Diep;Dongdong Ma;Rahul C. Deo;Teresa M. Holm

  • The Wilms tumor suppressor WT1 regulates early gonad development by activation of Sf1

    Dagmar Wilhelm;Christoph Englert

  • Insights into Sex Chromosome Evolution and Aging from the Genome of a Short-Lived Fish.

    Kathrin Reichwald;Andreas Petzold;Philipp Koch;Bryan R Downie

  • The Wilms tumor suppressor gene wt1 is required for development of the spleen

    Ute Herzer;Alexander Crocoll;Debra Barton;Norma Howells

  • Expression of the hTERT gene is regulated at the level of transcriptional initiation and repressed by Mad1.

    Çagatay Günes;Serge Lichtsteiner;Alain P. Vasserot;Christoph Englert

  • Focal segmental glomerulosclerosis is induced by microRNA-193a and its downregulation of WT1.

    Christoph A. Gebeshuber;Christoph Kornauth;Lihua Dong;Ralph Sierig

  • The Aeronomy of Ice in the Mesosphere (AIM) mission: Overview and early science results

    James M. Russell;Scott M. Bailey;Larry L. Gordley;David W. Rusch

  • WT1-Mediated Growth Suppression of Wilms Tumor Cells Expressing a WT1 Splicing Variant

    D. A. Haber;S. Park;Shyamala Maheswaran;C. Englert

  • Pharmapolymers in the 21st century: Synthetic polymers in drug delivery applications

    Christoph Englert;Johannes C. Brendel;Tobias C. Majdanski;Turgay Yildirim

  • The PGD2 pathway, independently of FGF9, amplifies SOX9 activity in Sertoli cells during male sexual differentiation.

    Brigitte Moniot;Faustine Declosmenil;Francisco Barrionuevo;Gerd Scherer

  • Truncated WT1 mutants alter the subnuclear localization of the wild-type protein

    Christoph Englert;Marc Vidal;Shyamala Maheswaran;Yimin Ge

Frequent Co-Authors

Daniel A. Haber
Daniel A. Haber Harvard University
Shyamala Maheswaran
Shyamala Maheswaran Harvard University
Marco Groth
Marco Groth Leibniz Institute on Aging – Fritz Lipmann Institute
Matthias Platzer
Matthias Platzer Leibniz Association
Jonathan J. Makela
Jonathan J. Makela University of Illinois at Urbana-Champaign
Michael Ristow
Michael Ristow École Polytechnique Fédérale de Lausanne
Reinhard Guthke
Reinhard Guthke Leibniz Association
Stefan Taudien
Stefan Taudien Universitätsmedizin Göttingen
Ulrich S. Schubert
Ulrich S. Schubert Friedrich Schiller University Jena
Manfred Schartl
Manfred Schartl University of Würzburg

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