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Genetics

D-Index
73
Citations
29361
World Ranking
2009
National Ranking
36

Overview

Philipp Bucher is affiliated with the École Polytechnique Fédérale de Lausanne in Switzerland. Their research primarily focuses on the fields of Biochemistry, Genetics, and Molecular Biology. Within these broader areas, Bucher has contributed extensively to subfields including Molecular Biology, Immunology and Allergy, Cancer Research, Cell Biology, and Genetics.

Their work covers several topics related to molecular and cellular processes. Key topics of study include:

  • Genomics and Chromatin Dynamics
  • RNA and protein synthesis mechanisms
  • RNA modifications and cancer
  • Cell Adhesion Molecules Research
  • Angiogenesis and VEGF in Cancer
  • RNA Research and Splicing
  • Cancer-related molecular mechanisms research

Bucher's publication record features papers in a variety of scientific venues, with frequent appearances in:

  • Zenodo (CERN European Organization for Nuclear Research)
  • bioRxiv (Cold Spring Harbor Laboratory)
  • EMBO Molecular Medicine
  • Genome biology
  • Nature Communications

Some notable recent publications include:

  • Insights gained from a comprehensive all-against-all transcription factor binding motif benchmarking study, 2020, Genome biology
  • The secreted protease Adamts18 links hormone action to activation of the mammary stem cell niche, 2020, Nature Communications
  • Intraductal xenografts show lobular carcinoma cells rely on their own extracellular matrix and LOXL1, 2021, EMBO Molecular Medicine
  • Contraceptive progestins with androgenic properties stimulate breast epithelial cell proliferation, 2021, EMBO Molecular Medicine
  • Extensive binding of uncharacterized human transcription factors to genomic dark matter, 2024, bioRxiv (Cold Spring Harbor Laboratory)

Their research collaborations include frequent co-authorship with several scientists, among whom are:

  • Ivan V. Kulakovskiy
  • Giovanna Ambrosini
  • Ilya E. Vorontsov
  • Jan Grau
  • Ivo Große

Best Publications

  • The InterPro Database, 2003 brings increased coverage and new features

    Nicola J Mulder;Rolf Apweiler;Teresa K Attwood;Amos Marc Bairoch

  • The PROSITE database, its status in 1997

    Amos Marc Bairoch;Philip Bucher;Kay Hofmann

  • Weight matrix descriptions of four eukaryotic RNA polymerase II promoter elements derived from 502 unrelated promoter sequences

    Philipp Bucher

  • The PROSITE database, its status in 1999.

    Kay Hofmann;Philip Bucher;Laurent Falquet;Amos Marc Bairoch

  • The InterPro database, an integrated documentation resource for protein families, domains and functional sites

    Rolf Apweiler;Terri K. Attwood;Amos Bairoch;Alex Bateman

  • The PROSITE database, its status in 2002.

    Laurent Falquet;Marco Pagni;Philipp Bucher;Nicolas Hulo

  • ESTScan: A Program for Detecting, Evaluating, and Reconstructing Potential Coding Regions in EST Sequences

    Christian Iseli;C. Victor Jongeneel;Philipp Bucher

  • PROSITE: A documented database using patterns and profiles as motif descriptors

    Christian Sigrist;Lorenzo Cerutti;Nicolas Hulo;Alexandre Gattiker

  • A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins.

    Peer Bork;Kay Hofmann;Philipp Bucher;Andrew F. Neuwald

  • The CARD domain: a new apoptotic signalling motif.

    Kay Hofmann;Philipp Bucher;Jurg Tschopp

  • Recent improvements to the PROSITE database.

    Nicolas Hulo;Christian J. A. Sigrist;Virginie Le Saux;Petra S. Langendijk-Genevaux

  • The UBA domain: a sequence motif present in multiple enzyme classes of the ubiquitination pathway

    Kay Hofmann;Philipp Bucher

  • Methods and algorithms for statistical analysis of protein sequences.

    V Brendel;P Bucher;I R Nourbakhsh;B E Blaisdell

  • DNA binding specificity of different STAT proteins: Comparison of in vitro specificity with natural target sites

    Georg B. Ehret;Patrick Reichenbach;Ulrike Schindler;Curt M. Horvath

  • The FHA domain: a putative nuclear signalling domain found in protein kinases and transcription factors

    Kay Hofmann;Philipp Bucher

  • Compilation and analysis of eukaryotic POL II promoter sequences.

    Philipp Bucher;Edward N. Trifonov

  • A flexible motif search technique based on generalized profiles

    Philipp Bucher;Kevin Karplus;Nicolas Moeri;Kay Hofmann

  • The PROSITE Database, Its Status in 1995

    Amos Marc Bairoch;Philip Bucher;Kay Hofmann

  • The PCI domain: a common theme in three multiprotein complexes.

    Kay Hofmann;Philipp Bucher

  • A conserved domain is present in different families of vesicular fusion proteins: A new superfamily

    Thomas Weimbs;Seng Hui Low;Steven J. Chapin;Keith E. Mostov

Frequent Co-Authors

C. Victor Jongeneel
C. Victor Jongeneel University of Illinois at Urbana-Champaign
Kay Hofmann
Kay Hofmann University of Cologne
Bernard M. E. Moret
Bernard M. E. Moret École Polytechnique Fédérale de Lausanne
Nicolas Mermod
Nicolas Mermod University of Lausanne
Cedric Notredame
Cedric Notredame Pompeu Fabra University
Amos Marc Bairoch
Amos Marc Bairoch Swiss Institute of Bioinformatics
Mauro Delorenzi
Mauro Delorenzi University of Lausanne
Samuel Karlin
Samuel Karlin Stanford University
Brian Stevenson
Brian Stevenson University of Kentucky
Stylianos E. Antonarakis
Stylianos E. Antonarakis University of Geneva

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