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Genetics

D-Index
54
Citations
25424
World Ranking
3606
National Ranking
241

Overview

Edgar Wingender is affiliated with the University of Göttingen in Germany and has an extensive publication record in the fields of Biochemistry, Genetics and Molecular Biology, Medicine, and Computer Science. Their research spans core molecular biology, cancer research, genetics, artificial intelligence, and computational theory and mathematics.

Their recent work includes a variety of papers focusing on biomedical text mining, cancer biology, and machine learning applications in genomics and clinical outcome prediction. Notable publications include:

  • Text mining-based word representations for biomedical data analysis and protein-protein interaction networks in machine learning tasks, 2021, PLoS ONE
  • NERO: a biomedical named-entity (recognition) ontology with a large, annotated corpus reveals meaningful associations through text embedding, 2021, npj Systems Biology and Applications
  • IGFBP2 Is a Potential Master Regulator Driving the Dysregulated Gene Network Responsible for Short Survival in Glioblastoma Multiforme, 2021, Frontiers in Genetics
  • High-Throughput Profiling of Colorectal Cancer Liver Metastases Reveals Intra- and Inter-Patient Heterogeneity in the EGFR and WNT Pathways Associated with Clinical Outcome, 2022, Cancers
  • Machine Learning based Survival Group Prediction in Glioblastoma, 2022, Preprints.org

The core topics of their research cover:

  • Biomedical Text Mining and Ontologies
  • Cancer, Hypoxia, and Metabolism
  • Glioma Diagnosis and Treatment
  • Bioinformatics and Genomic Networks
  • Computational Drug Discovery Methods
  • Topic Modeling
  • Natural Language Processing Techniques

Wingender has frequently published in venues such as:

  • Preprints.org
  • PLoS ONE
  • bioRxiv (Cold Spring Harbor Laboratory)
  • npj Systems Biology and Applications
  • Frontiers in Genetics

Their collaborations often involve co-authors including Tim Beißbarth, Darius Wlochowitz, Halima Alachram, Alexander Kel, and Hryhorii Chereda. Wingender's work integrates computational methods with biological problem-solving, applying machine learning and text mining approaches to genetics and cancer research.

Best Publications

  • TRANSFAC® and its module TRANSCompel®: transcriptional gene regulation in eukaryotes

    V. Matys;Olga V. Kel-Margoulis;Ellen Fricke;Ines Liebich

  • MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data.

    Kerstin Quandt;Kornelie Frech;Holger Karas;Edgar Wingender

  • TRANSFAC®: transcriptional regulation, from patterns to profiles

    V. Matys;Ellen Fricke;R. Geffers;Ellen Gößling

  • Databases on transcriptional regulation: TRANSFAC, TRRD and COMPEL

    T. Heinemeyer;E. Wingender;I. Reuter;H. Hermjakob

  • TRANSFAC: an integrated system for gene expression regulation

    Edgar Wingender;Xin Chen;Reinhard Hehl;Holger Karas

  • MATCHTM: a tool for searching transcription factor binding sites in DNA sequences

    Alexander E. Kel;Ellen Gößling;Ingmar Reuter;Evgeny Cheremushkin

  • TRANSFAC: a database on transcription factors and their DNA binding sites.

    Edgar Wingender;P. Dietze;Holger Karas;Rainer Knüppel

  • The TRANSFAC system on gene expression regulation.

    Edgar Wingender;Xin Chen;Ellen Fricke;R. Geffers

  • The BioPAX community standard for pathway data sharing

    Emek Demir;Emek Demir;Michael P. Cary;Suzanne Paley;Ken Fukuda

  • Defined Engineered Human Myocardium With Advanced Maturation for Applications in Heart Failure Modeling and Repair.

    Malte Tiburcy;James E. Hudson;Paul Balfanz;Susanne Schlick

  • The TRANSFAC project as an example of framework technology that supports the analysis of genomic regulation

    Edgar Wingender

  • Expanding the TRANSFAC database towards an expert system of regulatory molecular mechanisms

    T. Heinemeyer;X. Chen;H. Karas;A. E. Kel

  • Compilation of transcription regulating proteins

    Edgar Wingender

  • PRODORIC: prokaryotic database of gene regulation

    Richard Münch;Karsten Hiller;Heiko Barg;Dana Heldt

  • Computer-assisted identification of cell cycle-related genes: New targets for E2F transcription factors

    Alexander E. Kel;Olga V. Kel-Margoulis;Peggy J. Farnham;Stephanie M. Bartley

  • TRANSPATH: an information resource for storing and visualizing signaling pathways and their pathological aberrations.

    Mathias Krull;Susanne Pistor;Nico Voss;Alexander E. Kel

  • The Human Immunodeficiency Virus Type 1 Encoded Vpu Protein is Phosphorylated by Casein Kinase-2 (CK-2) at Positions Ser52 and Ser56 within a Predicted α-Helix-Turn-α-Helix-Motif

    Ulrich Schubert;Peter Henklein;Brigitte Boldyreff;Edgar Wingender

  • TRANSFAC, TRRD and COMPEL: towards a federated database system on transcriptional regulation

    E. Wingender;A. E. Kel;O. V. Kel;H. Karas

  • TFClass: an expandable hierarchical classification of human transcription factors

    Edgar Wingender;Torsten Schoeps;Jürgen Dönitz

  • Recognition of NFATp/AP-1 composite elements within genes induced upon the activation of immune cells.

    Alexander Kel;Olga Kel-Margoulis;Vladimir Babenko;Edgar Wingender

Frequent Co-Authors

Edwin De Pauw
Edwin De Pauw University of Liège
Hermona Soreq
Hermona Soreq Hebrew University of Jerusalem
Dieter Jahn
Dieter Jahn Technische Universität Braunschweig
Antoine Depaulis
Antoine Depaulis Grenoble Alpes University
Dietmar Schomburg
Dietmar Schomburg Technische Universität Braunschweig
Chris Sander
Chris Sander Harvard University
Gary D. Bader
Gary D. Bader University of Toronto
Peter D. Karp
Peter D. Karp SRI International
Michael Hucka
Michael Hucka California Institute of Technology
Peter D'Eustachio
Peter D'Eustachio New York University

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