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Microbiology

D-Index
54
Citations
9755
World Ranking
3982
National Ranking
1542

Overview

Ana Fernandez-Sesma is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research primarily spans the field of Medicine, with a significant focus on Infectious Diseases, Immunology, and Public Health, Environmental and Occupational Health. Molecular Biology and Neurology also feature as important subfields in their body of work.

The scientist's recent papers cover topics related to immune responses, viral infections, and vaccine development. Notable publications include:

  • Transcriptional atlas of the human immune response to 13 vaccines reveals a common predictor of vaccine-induced antibody responses (2022, Nature Immunology)
  • Pan-vaccine analysis reveals innate immune endotypes predictive of antibody responses to vaccination (2022, Nature Immunology)
  • Chikungunya virus antagonizes cGAS-STING mediated type-I interferon responses by degrading cGAS (2020, PLoS Pathogens)
  • Challenges on the development of a dengue vaccine: a comprehensive review of the state of the art (2023, Journal of General Virology)
  • Immunophenotyping assessment in a COVID-19 cohort (IMPACC): A prospective longitudinal study (2021, Science Immunology)

Ana Fernandez-Sesma frequently collaborates with several coauthors, including Ofer Levy, Steven H. Kleinstein, Ruth R. Montgomery, Bali Pulendran, and Rafick-Pierre Sékaly. These collaborations shape much of the scientist's academic output.

Their work appears predominantly in specific publication venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • mSphere
  • JCI Insight
  • Nature Immunology
  • Journal of Virology

Main topics in Ana Fernandez-Sesma's research include SARS-CoV-2 and COVID-19 research, mosquito-borne diseases and control, viral infections and vectors, interferon and immune responses, COVID-19 clinical research studies, long-term effects of COVID-19, and insect symbiosis and bacterial influences.

Best Publications

  • DENV inhibits type I IFN production in infected cells by cleaving human STING.

    Sebastian Aguirre;Ana M. Maestre;Sarah Pagni;Jenish R. Patel

  • Influenza Virus Evades Innate and Adaptive Immunity via the NS1 Protein

    Ana Fernandez-Sesma;Svetlana Marukian;Barbara J. Ebersole;Dorothy Kaminski

  • Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection.

    Sebastian Aguirre;Priya Luthra;Maria T Sanchez-Aparicio;Ana M Maestre

  • Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis

    Priya S. Shah;Nichole Link;Gwendolyn M. Jang;Gwendolyn M. Jang;Phillip P. Sharp

  • The E3-Ligase TRIM Family of Proteins Regulates Signaling Pathways Triggered by Innate Immune Pattern-Recognition Receptors

    Gijs A. Versteeg;Ricardo Rajsbaum;Maria Teresa Sánchez-Aparicio;Ana M. Maestre

  • Type I IFN Modulates Innate and Specific Antiviral Immunity

    J E Durbin;A Fernandez-Sesma;C K Lee;T D Rao

  • The Influenza Virus Protein PB1-F2 Inhibits the Induction of Type I Interferon at the Level of the MAVS Adaptor Protein

    Zsuzsanna T. Varga;Irene Ramos;Rong Hai;Mirco Schmolke

  • SAMHD1-deficient CD14+ cells from individuals with Aicardi-Goutières syndrome are highly susceptible to HIV-1 infection.

    André Berger;Andreas F. R. Sommer;Jenny Zwarg;Matthias Hamdorf

  • Defining Hsp70 Subnetworks in Dengue Virus Replication Reveals Key Vulnerability in Flavivirus Infection

    Shuhei Taguwa;Kevin Maringer;Kevin Maringer;Xiaokai Li;Dabeiba Bernal-Rubio

  • Dengue Virus Co-opts UBR4 to Degrade STAT2 and Antagonize Type I Interferon Signaling

    Juliet Morrison;Maudry Laurent-Rolle;Ana M. Maestre;Ricardo Rajsbaum

  • A novel Zika virus mouse model reveals strain specific differences in virus pathogenesis and host inflammatory immune responses

    Shashank Tripathi;Vinod R. M. T. Balasubramaniam;Julia A. Brown;Ignacio Mena

  • Mouse STAT2 Restricts Early Dengue Virus Replication

    Joseph Ashour;Juliet Morrison;Maudry Laurent-Rolle;Alan Belicha-Villanueva

  • Inhibition of the type I interferon response in human dendritic cells by dengue virus infection requires a catalytically active NS2B3 complex.

    Juan R. Rodriguez-Madoz;Alan Belicha-Villanueva;Dabeiba Bernal-Rubio;Joseph Ashour

  • Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response.

    Ricardo Rajsbaum;Gijs A. Versteeg;Gijs A. Versteeg;Sonja Schmid;Ana M. Maestre

  • Interleukin-4 causes delayed virus clearance in influenza virus-infected mice.

    T M Moran;H Isobe;A Fernandez-Sesma;J L Schulman

  • Innate Immunity Evasion by Dengue Virus

    Juliet Morrison;Sebastian Aguirre;Ana Fernandez-Sesma

  • Th2 Responses to Inactivated Influenza Virus Can Be Converted to Th1 Responses and Facilitate Recovery from Heterosubtypic Virus Infection

    Thomas M. Moran;Helen Park;Ana Fernandez-Sesma;Jerome L. Schulman

  • Dengue Virus Inhibits the Production of Type I Interferon in Primary Human Dendritic Cells

    Juan R. Rodriguez-Madoz;Dabeiba Bernal-Rubio;Dorota Kaminski;Kelley Boyd

  • Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection

    Nicholas S. Heaton;Natasha Moshkina;Romain Fenouil;Thomas J. Gardner

  • The NS1 Protein of a Human Influenza Virus Inhibits Type I Interferon Production and the Induction of Antiviral Responses in Primary Human Dendritic and Respiratory Epithelial Cells

    Kester Haye;Svetlana Burmakina;Thomas Moran;Adolfo García-Sastre

  • Protection against Respiratory Syncytial Virus by a Recombinant Newcastle Disease Virus Vector

    Luis Martinez-Sobrido;Negin Gitiban;Ana Fernandez-Sesma;Jerome Cros

Frequent Co-Authors

Adolfo García-Sastre
Adolfo García-Sastre Icahn School of Medicine at Mount Sinai
Thomas M. Moran
Thomas M. Moran Icahn School of Medicine at Mount Sinai
Viviana Simon
Viviana Simon Icahn School of Medicine at Mount Sinai
Stuart C. Sealfon
Stuart C. Sealfon Icahn School of Medicine at Mount Sinai
Andrew D. Davidson
Andrew D. Davidson University of Bristol
Peter Palese
Peter Palese Icahn School of Medicine at Mount Sinai
Florian Krammer
Florian Krammer Icahn School of Medicine at Mount Sinai
Christopher F. Basler
Christopher F. Basler University of Georgia
Andrea V. Gamarnik
Andrea V. Gamarnik Fundación Instituto Leloir
Nevan J. Krogan
Nevan J. Krogan University of California, San Francisco

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