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David M. Bedwell

D-Index & Metrics

Biology and Biochemistry

D-Index
49
Citations
8547
World Ranking
18035
National Ranking
7377

David M. Bedwell publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where David M. Bedwell sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 106 publications — 7th percentile

7% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

David M. Bedwell D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where David M. Bedwell sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 49 D-Index — 9th percentile

9% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

David M. Bedwell is affiliated with the University of Alabama at Birmingham in the United States. Their research focuses primarily on the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions in Molecular Biology, Pulmonary and Respiratory Medicine, Neurology, Genetics, and Oncology.

The scientist's work encompasses several key topics, including:

  • Neurofibromatosis and Schwannoma Cases
  • RNA and protein synthesis mechanisms
  • Cystic Fibrosis Research Advances
  • RNA modifications and cancer
  • Neuroblastoma Research and Treatments
  • Neonatal Respiratory Health Research
  • CRISPR and Genetic Engineering

David M. Bedwell has published extensively, with the majority appearing in the Journal of Cystic Fibrosis. Other frequent publication venues include Nature Communications, Molecular Therapy - Nucleic Acids, PLoS ONE, and the American Journal of Physiology-Lung Cellular and Molecular Physiology.

Notable recent papers include:

  • A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion, 2021, Nature Communications
  • Mutation-Directed Therapeutics for Neurofibromatosis Type I, 2020, Molecular Therapy - Nucleic Acids
  • Extended stop codon context predicts nonsense codon readthrough efficiency in human cells, 2024, Nature Communications
  • Prime editing-mediated correction of the CFTR W1282X mutation in iPSCs and derived airway epithelial cells, 2023, PLoS ONE
  • The synthetic aminoglycoside ELX-02 induces readthrough of G550X-CFTR producing superfunctional protein that can be further enhanced by CFTR modulators, 2023, American Journal of Physiology-Lung Cellular and Molecular Physiology

The scientist has collaborated frequently with peers such as Kim M. Keeling, K. Thrasher, Lianwu Fu, Steven M. Rowe, and Ming Du, indicating a network of coauthorship that supports interdisciplinary research efforts.

Best Publications

  • Aminoglycoside antibiotics restore CFTR function by overcoming premature stop mutations

    Marybeth Howard;Raymond A. Frizzell;Raymond A. Frizzell;David M. Bedwell

  • Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system.

    Marina Manuvakhova;Kim Keeling;David M. Bedwell

  • SUPPRESSION OF A CFTR PREMATURE STOP MUTATION IN A BRONCHIAL EPITHELIAL CELL LINE

    David M. Bedwell;Anisa Kaenjak;Dale J. Benos;Zsuzsa Bebok

  • The efficiency of translation termination is determined by a synergistic interplay between upstream and downstream sequences in Saccharomyces cerevisiae.

    Brian Bonetti;Lianwu Fu;James Moon;David M. Bedwell

  • Therapeutics Based on Stop Codon Readthrough

    Kim M. Keeling;Xiaojiao Xue;Gwen Gunn;David M. Bedwell

  • Evidence that Systemic Gentamicin Suppresses Premature Stop Mutations in Patients with Cystic Fibrosis

    J. P. Clancy;Zsuzsa Bebök;Fadel Ruiz;Chris King

  • PTC124 is an orally bioavailable compound that promotes suppression of the human CFTR-G542X nonsense allele in a CF mouse model

    Ming Du;Xiaoli Liu;Ellen Marie Welch;Samit Hirawat

  • The spc rtbosomal protein operon of Eschenchia coli: sequence and cotranscriptlon of the rlbosomal protein genes and a protein export gene

    Douglas Pat Cerretti;Dennis Dean;Geneva R. Davis;David M. Bedwell

  • GTP Hydrolysis by eRF3 Facilitates Stop Codon Decoding during Eukaryotic Translation Termination

    Joe Salas-Marco;David M. Bedwell

  • Aminoglycoside suppression of a premature stop mutation in a Cftr-/- mouse carrying a human CFTR-G542X transgene.

    Ming Du;Julie R. Jones;Jessica Lanier;Kim M. Keeling

  • Gentamicin-mediated suppression of Hurler syndrome stop mutations restores a low level of alpha-L-iduronidase activity and reduces lysosomal glycosaminoglycan accumulation.

    Kim M. Keeling;Doug A. Brooks;John J. Hopwood;Peining Li

  • Ataluren stimulates ribosomal selection of near-cognate tRNAs to promote nonsense suppression.

    Bijoyita Roy;Westley J. Friesen;Yuki Tomizawa;John D. Leszyk

  • The vacuolar Ca2+/H+ exchanger Vcx1p/Hum1p tightly controls cytosolic Ca2+ levels in S. cerevisiae

    Attila Miseta;Richard Kellermayer;David P Aiello;Lianwu Fu

  • Leaky termination at premature stop codons antagonizes nonsense-mediated mRNA decay in S. cerevisiae.

    Kim M. Keeling;Jessica Lanier;Ming Du;Joe Salas-Marco

  • Characterization of defects in ion transport and tissue development in cystic fibrosis transmembrane conductance regulator (CFTR)-knockout rats.

    Katherine L. Tuggle;Susan E. Birket;Xiaoxia Cui;Jeong Hong

  • Clinically relevant aminoglycosides can suppress disease-associated premature stop mutations in the IDUA and P53 cDNAs in a mammalian translation system.

    Kim M. Keeling;David M. Bedwell

  • Synthetic Aminoglycosides Efficiently Suppress Cystic Fibrosis Transmembrane Conductance Regulator Nonsense Mutations and Are Enhanced by Ivacaftor

    Xiaojiao Xue;Venkateshwar Mutyam;Liping Tang;Silpak Biswas

  • Discrimination between defects in elongation fidelity and termination efficiency provides mechanistic insights into translational readthrough.

    Joe Salas-Marco;David M. Bedwell

  • Suppression of premature termination codons as a therapeutic approach

    Kim M. Keeling;Dan Wang;Sara E. Conard;David M. Bedwell

  • Suppression of nonsense mutations as a therapeutic approach to treat genetic diseases.

    Kim M. Keeling;David M. Bedwell

Frequent Co-Authors

Steven M. Rowe
Steven M. Rowe University of Alabama at Birmingham
Eric J. Sorscher
Eric J. Sorscher Emory University
Masayasu Nomura
Masayasu Nomura University of Wisconsin–Madison
John P. Clancy
John P. Clancy Cystic Fibrosis Foundation
Raymond A. Frizzell
Raymond A. Frizzell University of Pittsburgh
Scott D. Emr
Scott D. Emr Cornell University
Allan Jacobson
Allan Jacobson University of Massachusetts Chan Medical School
Dale J. Benos
Dale J. Benos University of Alabama at Birmingham
Bruce R. Korf
Bruce R. Korf University of Alabama at Birmingham
Philip J. Farabaugh
Philip J. Farabaugh University of Maryland, Baltimore County

External Links

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Best Scientists Citing David M. Bedwell

Steven M. Rowe

Steven M. Rowe

University of Alabama at Birmingham

Publications: 49

Allan Jacobson

Allan Jacobson

University of Massachusetts Chan Medical School

Publications: 27

Eric J. Sorscher

Eric J. Sorscher

Emory University

Publications: 24

John P. Clancy

John P. Clancy

Cystic Fibrosis Foundation

Publications: 22

Isabelle Sermet-Gaudelus

Isabelle Sermet-Gaudelus

Necker-Enfants Malades Hospital

Publications: 20

Andreas E. Kulozik

Andreas E. Kulozik

Heidelberg University

Publications: 17

Sadis Matalon

Sadis Matalon

University of Alabama at Birmingham

Publications: 16

John F. Atkins

John F. Atkins

University College Cork

Publications: 16

Kendal D. Hirschi

Kendal D. Hirschi

Baylor College of Medicine

Publications: 14

David E. Draper

David E. Draper

Johns Hopkins University

Publications: 13

Mick F. Tuite

Mick F. Tuite

University of Kent

Publications: 13

James F. Collawn

James F. Collawn

University of Alabama at Birmingham

Publications: 13

Pamela L. Zeitlin

Pamela L. Zeitlin

National Jewish Health

Publications: 12

Marcus A. Mall

Marcus A. Mall

Charité - University Medicine Berlin

Publications: 12

Rachel Green

Rachel Green

Johns Hopkins University School of Medicine

Publications: 11

Batsheva Kerem

Batsheva Kerem

Hebrew University of Jerusalem

Publications: 11

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