D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 50 Citations 15,950 83 World Ranking 1763 National Ranking 894

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Cancer

Richard J. Gregory spends much of his time researching Cystic fibrosis transmembrane conductance regulator, Chloride channel, Cystic fibrosis, Cell biology and Molecular biology. Richard J. Gregory merges many fields, such as Cystic fibrosis transmembrane conductance regulator and Membrane protein, in his writings. As a part of the same scientific family, he mostly works in the field of Chloride channel, focusing on Mutation and, on occasion, Apical membrane and Transfection.

His Cystic fibrosis research integrates issues from Endocrinology and Mutant. His Cell biology research incorporates elements of Angiogenesis and Immunology. Richard J. Gregory has included themes like Genetic enhancement and Heterologous expression in his Molecular biology study.

His most cited work include:

  • Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis (1538 citations)
  • Demonstration that CFTR is a Chloride Channel by Alteration of its Anion Selectivity (940 citations)
  • Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis (660 citations)

What are the main themes of his work throughout his whole career to date?

Molecular biology, Cystic fibrosis transmembrane conductance regulator, Genetic enhancement, Cell biology and Vector are his primary areas of study. The concepts of his Molecular biology study are interwoven with issues in Transgene, Recombinant DNA, Expression vector, Viral vector and Gene. The Cystic fibrosis transmembrane conductance regulator study combines topics in areas such as Chloride channel, Peptide sequence and Mutant.

His Genetic enhancement research is multidisciplinary, relying on both Tropism, Cancer research, Vectors in gene therapy and Virology. His Cell biology study integrates concerns from other disciplines, such as Binding domain, Transcription factor, Transactivation, Transfection and Immunology. His Cystic fibrosis research is multidisciplinary, relying on both Apical membrane and Endocrinology.

He most often published in these fields:

  • Molecular biology (38.32%)
  • Cystic fibrosis transmembrane conductance regulator (25.23%)
  • Genetic enhancement (22.43%)

What were the highlights of his more recent work (between 2002-2021)?

  • Molecular biology (38.32%)
  • Transgene (17.76%)
  • Antibody (9.35%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Molecular biology, Transgene, Antibody, Pharmacology and Cell biology. His Molecular biology research is multidisciplinary, incorporating elements of Gene expression, Gene, Vector, Cytochrome c and Viral vector. His work in Vector addresses subjects such as Insert, which are connected to disciplines such as Recombinant DNA.

His work carried out in the field of Transgene brings together such families of science as Reactive oxygen species, Cardiotoxicity, Genetic enhancement and Immune system. He combines subjects such as Caspase 3, Caspase-9, Caspase 8, Fas ligand and Viability assay with his study of Cell biology. In his study, Immunology is strongly linked to Regulation of gene expression, which falls under the umbrella field of Immune tolerance.

Between 2002 and 2021, his most popular works were:

  • Hypoxia-Inducible Factor-1 Mediates Activation of Cultured Vascular Endothelial Cells by Inducing Multiple Angiogenic Factors (265 citations)
  • AAV2 Vector Harboring a Liver-Restricted Promoter Facilitates Sustained Expression of Therapeutic Levels of α-Galactosidase A and the Induction of Immune Tolerance in Fabry Mice (146 citations)
  • Targeting adenoviral vectors using heterofunctional polyethylene glycol FGF2 conjugates (105 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Cancer

Richard J. Gregory mostly deals with Genetic enhancement, Molecular biology, Transgene, Angiogenesis and Immunology. His study in Genetic enhancement is interdisciplinary in nature, drawing from both Vector, Antibody and Immune system, Immune tolerance. His Molecular biology study combines topics from a wide range of disciplines, such as Tropism, Virus, T cell, Viral vector and Gene delivery.

His Angiopoietin receptor study in the realm of Angiogenesis interacts with subjects such as Vascular endothelial growth factor C and Clear cell. His studies deal with areas such as Ischemic preconditioning, Adenoviridae, Hemangioblastoma and Adenocarcinoma as well as Immunology. His work deals with themes such as Endocrinology and Internal medicine, which intersect with Cell biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

Seng H. Cheng;Richard J. Gregory;John Marshall;Sucharita Paul.
Cell (1990)

2065 Citations

Demonstration That CFTR Is a Chloride Channel by Alteration of Its Anion Selectivity

Matthew P. Anderson;Richard J. Gregory;Simon Thompson;David W. Souza.
Science (1991)

1333 Citations

Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis

Joseph Zabner;Larry A. Couture;Richard J. Gregory;Scott M. Graham.
Cell (1993)

803 Citations

Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells.

Devra P. Rich;Matthew P. Anderson;Richard J. Gregory;Seng H. Cheng.
Nature (1990)

801 Citations

Generation of cAMP-activated chloride currents by expression of CFTR

Matthew P. Anderson;Devra P. Rich;Richard J. Gregory;Alan E. Smith.
Science (1991)

700 Citations

Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel.

S.H. Cheng;D.P. Rich;J. Marshall;R.J. Gregory.
Cell (1991)

700 Citations

Gene therapy for cystic fibrosis

Richard J. Gregory;Donna Armentano;Larry A. Couture;Alan E. Smith.
(1993)

688 Citations

Nucleoside triphosphates are required to open the CFTR chloride channel

Matthew P. Anderson;Herbert A. Berger;Devra P. Rich;Richard J. Gregory.
Cell (1991)

676 Citations

Mutations in CFTR associated with mild-disease-form Cl- channels with altered pore properties.

David N. Sheppard;Devra P. Rich;Lynda S. Ostedgaard;Richard J. Gregory;Richard J. Gregory.
Nature (1993)

644 Citations

Recombinant adenoviral vector and methods of use

Richard J. Gregory;Ken N. Wills;Daniel C. Maneval.
(1994)

497 Citations

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