David A. Stoltz

Overview

Best Publications

• Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung

  Alejandro A. Pezzulo;Xiao Xiao Tang;Mark J. Hoegger;Mahmoud H. Abou Alaiwa

  951
  Citations

• Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs.

  Christopher S. Rogers;David A. Stoltz;David K. Meyerholz;Lynda S. Ostedgaard

  899
  Citations

• Origins of Cystic Fibrosis Lung Disease

  David A. Stoltz;David K. Meyerholz;Michael J. Welsh

  763
  Citations

• Cystic Fibrosis Pigs Develop Lung Disease and Exhibit Defective Bacterial Eradication at Birth

  David A. Stoltz;David K. Meyerholz;Alejandro A. Pezzulo;Shyam Ramachandran

  576
  Citations

• Production of CFTR-null and CFTR-ΔF508 heterozygous pigs by adeno-associated virus–mediated gene targeting and somatic cell nuclear transfer

  Christopher S. Rogers;Yanhong Hao;Tatiana Rokhlina;Melissa Samuel

  494
  Citations

• IL-17 Stimulates Granulopoiesis in Mice: Use of an Alternate, Novel Gene Therapy-Derived Method for In Vivo Evaluation of Cytokines

  P. Schwarzenberger;V. La Russa;A. Miller;Peng Ye

  399
  Citations

• Impaired mucus detachment disrupts mucociliary transport in a piglet model of cystic fibrosis

  Mark J. Hoegger;Anthony J. Fischer;James D. McMenimen;Lynda S. Ostedgaard

  395
  Citations

• Restoring Cystic Fibrosis Transmembrane Conductance Regulator Function Reduces Airway Bacteria and Inflammation in People with Cystic Fibrosis and Chronic Lung Infections

  Katherine B. Hisert;Sonya L. Heltshe;Christopher Pope;Peter Jorth

  371
  Citations

• Airway acidification initiates host defense abnormalities in cystic fibrosis mice

  Viral S. Shah;Viral S. Shah;David K. Meyerholz;Xiao Xiao Tang;Xiao Xiao Tang;Leah Reznikov

  323
  Citations

• The porcine lung as a potential model for cystic fibrosis.

  Christopher S. Rogers;William M. Abraham;Kim A. Brogden;John F. Engelhardt

  308
  Citations

• Loss of anion transport without increased sodium absorption characterizes newborn porcine cystic fibrosis airway epithelia.

  Jeng-Haur Chen;David A. Stoltz;Philip H. Karp;Sarah E. Ernst

  262
  Citations

• Acidic pH increases airway surface liquid viscosity in cystic fibrosis

  Xiao Xiao Tang;Lynda S. Ostedgaard;Mark J. Hoegger;Thomas O. Moninger

  257
  Citations

• The ΔF508 Mutation Causes CFTR Misprocessing and Cystic Fibrosis-Like Disease in Pigs

  Lynda S. Ostedgaard;David K. Meyerholz;Jeng Haur Chen;Alejandro A. Pezzulo

  236
  Citations

• pH modulates the activity and synergism of the airway surface liquid antimicrobials β-defensin-3 and LL-37

  Mahmoud H. Abou Alaiwa;Leah R. Reznikov;Nicholas D. Gansemer;Kelsey A. Sheets

  223
  Citations

• Delayed neutrophil apoptosis enhances NET formation in cystic fibrosis.

  Robert D Gray;Gareth Hardisty;Kate H Regan;Maeve Smith

  215
  Citations

• Loss of Cystic Fibrosis Transmembrane Conductance Regulator Function Produces Abnormalities in Tracheal Development in Neonatal Pigs and Young Children

  David K. Meyerholz;David A. Stoltz;Eman Namati;Shyam Ramachandran

  209
  Citations

• Cystic fibrosis transmembrane conductance regulator intracellular processing, trafficking, and opportunities for mutation-specific treatment.

  Mark P. Rogan;David A. Stoltz;Douglas B. Hornick

  201
  Citations

• Pathology of gastrointestinal organs in a porcine model of cystic fibrosis.

  David K. Meyerholz;David A. Stoltz;Alejandro A. Pezzulo;Michael J. Welsh

  181
  Citations

• Paraoxonase-2 deficiency enhances Pseudomonas aeruginosa quorum sensing in murine tracheal epithelia.

  David A. Stoltz;Egon A. Ozer;Carey J. Ng;Janet M. Yu

  171
  Citations

• Gel-forming mucins form distinct morphologic structures in airways.

  Lynda S. Ostedgaard;Thomas O. Moninger;James D. McMenimen;Nicholas M. Sawin

  150
  Citations