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Biology and Biochemistry

D-Index
81
Citations
24857
World Ranking
3871
National Ranking
1919

Overview

Sylvia M. Evans is affiliated with the University of Montana in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with significant contributions to Medicine. Their work encompasses several subfields, notably Molecular Biology, Cardiology and Cardiovascular Medicine, Genetics, Surgery, and Cell Biology.

Their main research topics include:

  • Congenital heart defects research
  • RNA modifications and cancer
  • Cardiomyopathy and Myosin Studies
  • Cardiovascular Function and Risk Factors
  • Genetics and Neurodevelopmental Disorders
  • Single-cell and spatial transcriptomics
  • Mitochondrial Function and Pathology

Sylvia M. Evans has published extensively with frequent contributions in the following venues:

  • Circulation
  • Circulation Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS Genetics
  • Cardiovascular Research

Recent notable publications include:

  • Spatially organized cellular communities form the developing human heart, 2024, Nature
  • Unveiling Complexity and Multipotentiality of Early Heart Fields, 2021, Circulation Research
  • Parallel Lineage-Tracing Studies Establish Fibroblasts as the Prevailing In Vivo Adipocyte Progenitor, 2020, Cell Reports
  • Loss of Filamin C Is Catastrophic for Heart Function, 2020, Circulation
  • Cardiolipin Remodeling Defects Impair Mitochondrial Architecture and Function in a Murine Model of Barth Syndrome Cardiomyopathy, 2021, Circulation Heart Failure

Collaborations form a significant part of their research approach. Frequent co-authors include:

  • Ju Chen
  • Lunfeng Zhang
  • Paola Cattaneo
  • Yusu Gu
  • Nuno Guimarães-Camboa

Best Publications

  • Isl1 Identifies a Cardiac Progenitor Population that Proliferates Prior to Differentiation and Contributes a Majority of Cells to the Heart

    Chen Leng Cai;Xingqun Liang;Yunqing Shi;Po Hsien Chu

  • Postnatal isl1 + cardioblasts enter fully differentiated cardiomyocyte lineages

    Karl Ludwig Laugwitz;Alessandra Moretti;Jason Lam;Peter Gruber

  • Multipotent Embryonic Isl1+ Progenitor Cells Lead to Cardiac, Smooth Muscle, and Endothelial Cell Diversification

    Alessandra Moretti;Leslie Caron;Atsushi Nakano;Jason T. Lam;Jason T. Lam

  • A myocardial lineage derives from Tbx18 epicardial cells

    Chen-Leng Cai;Jody C. Martin;Yunfu Sun;Li Cui

  • Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

    Tatiana Kisseleva;Min Cong;YongHan Paik;David Scholten

  • Resident fibroblast lineages mediate pressure overload–induced cardiac fibrosis

    Thomas Moore-Morris;Nuno Guimarães-Camboa;Indroneal Banerjee;Alexander C. Zambon

  • IL-11 is a crucial determinant of cardiovascular fibrosis

    Sebastian Schafer;Sivakumar Viswanathan;Anissa A Widjaja;Wei-Wen Lim

  • Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo

    Nuno Guimarães-Camboa;Nuno Guimarães-Camboa;Paola Cattaneo;Yunfu Sun;Thomas Moore-Morris

  • Nkx2-5 Pathways and Congenital Heart Disease: Loss of Ventricular Myocyte Lineage Specification Leads to Progressive Cardiomyopathy and Complete Heart Block

    Mohammad Pashmforoush;Jonathan T Lu;Hanying Chen;Tara St Amand

  • Transcriptional regulation during cardiac growth and development.

    K. R. Chien;Hong Zhu;K. U. Knowlton;W. Miller-Hance

  • Islet 1 is expressed in distinct cardiovascular lineages, including pacemaker and coronary vascular cells.

    Yunfu Sun;Xingqun Liang;Nader Najafi;Margaret Cass

  • The Renewal and Differentiation of Isl1+ Cardiovascular Progenitors Are Controlled by a Wnt/β-Catenin Pathway

    Yibing Qyang;Silvia Martin-Puig;Murali Chiravuri;Shuibing Chen

  • Co-regulation of the atrial natriuretic factor and cardiac myosin light chain-2 genes during alpha-adrenergic stimulation of neonatal rat ventricular cells. Identification of cis sequences within an embryonic and a constitutive contractile protein gene which mediate inducible expression.

    K U Knowlton;E Baracchini;R S Ross;A N Harris

  • CARP, a cardiac ankyrin repeat protein, is downstream in the Nkx2-5 homeobox gene pathway

    Y. Zou;S. Evans;J. Chen;H.C. Kuo

  • Ablation of Cypher, a PDZ-LIM domain Z-line protein, causes a severe form of congenital myopathy

    Q Zhou;P H Chu;C Huang;C F Cheng

  • Isl1Cre reveals a common Bmp pathway in heart and limb development

    Lei Yang;Chen Leng Cai;Lizhu Lin;Yibing Qyang

  • Myocardial lineage development

    Sylvia M. Evans;Deborah Yelon;Frank L. Conlon;Margaret L. Kirby

  • Required, Tissue-Specific Roles for Fgf8 in Outflow Tract Formation and Remodeling

    Eon Joo Park;Lisa A. Ogden;Amy Talbot;Sylvia Evans

  • β-Catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesis

    Lizhu Lin;Li Cui;Wenlai Zhou;Daniel Dufort

  • Cai et al. reply

    Chen-Leng Cai;Jody C. Martin;Yunfu Sun;Li Cui

Frequent Co-Authors

Ju Chen
Ju Chen University of California, San Diego
Kirk L. Peterson
Kirk L. Peterson University of California, San Diego
Kenneth R. Chien
Kenneth R. Chien Karolinska Institute
Michel Pucéat
Michel Pucéat Aix-Marseille University
Andrew D. McCulloch
Andrew D. McCulloch University of California, San Diego
Neil C. Chi
Neil C. Chi University of California, San Diego
Bin Zhou
Bin Zhou Chinese Academy of Sciences
William B. Stallcup
William B. Stallcup Discovery Institute
Samuel L. Pfaff
Samuel L. Pfaff Salk Institute for Biological Studies
Marcelo A. Nobrega
Marcelo A. Nobrega University of Chicago

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