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Biology and Biochemistry

D-Index
54
Citations
10161
World Ranking
15657
National Ranking
6528

Overview

David R. Hyde is affiliated with the University of Notre Dame in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a focus on Molecular Biology, Cell Biology, and Neurology as key subfields. The scientist's work addresses main topics including Retinal Development and Disorders, Zebrafish Biomedical Research Applications, Neuroinflammation and Neurodegeneration Mechanisms, Traumatic Brain Injury Research, and Neurogenesis and neuroplasticity mechanisms.

Recent publications by David R. Hyde include the following:

  • Gene regulatory networks controlling vertebrate retinal regeneration, 2020, Science
  • Reprogramming Müller Glia to Regenerate Retinal Neurons, 2020, Annual Review of Vision Science
  • Inflammation and matrix metalloproteinase 9 (Mmp-9) regulate photoreceptor regeneration in adult zebrafish, 2020, Glia
  • The Regenerating Adult Zebrafish Retina Recapitulates Developmental Fate Specification Programs, 2021, Frontiers in Cell and Developmental Biology
  • Notch3 and DeltaB maintain Müller glia quiescence and act as negative regulators of regeneration in the light-damaged zebrafish retina, 2020, Glia

The scientist often collaborates with other researchers, frequently co-authoring papers with Patrick Boyd, Leah J. Campbell, Seth Blackshaw, James Hentig, and Kaylee Cloghessy.

David R. Hyde publishes regularly in venues such as bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Cell and Developmental Biology, Journal of Visualized Experiments, UNC Libraries, and Glia. The body of work reflects a consistent interest in zebrafish as a model for retinal and neurological studies.

Best Publications

  • The zebrafish as a model for complex tissue regeneration

    Matthew Gemberling;Travis J. Bailey;David R. Hyde;Kenneth D. Poss

  • Light-induced rod and cone cell death and regeneration in the adult albino zebrafish (Danio rerio) retina.

    Thomas S. Vihtelic;David R. Hyde

  • Gene regulatory networks controlling vertebrate retinal regeneration

    Thanh Hoang;Jie Wang;Patrick Boyd;Fang Wang

  • The UV visual world of fishes: a review

    G. S. Losey;T. W. Cronin;T. H. Goldsmith;D. Hyde

  • Cloning and characterization of six zebrafish photoreceptor opsin cDNAs and immunolocalization of their corresponding proteins.

    Thomas S. Vihtelic;Christopher J. Doro;David R. Hyde

  • Tumor Necrosis Factor-Alpha Is Produced by Dying Retinal Neurons and Is Required for Müller Glia Proliferation during Zebrafish Retinal Regeneration

    Craig M. Nelson;Kristin M. Ackerman;Patrick O'Hayer;Travis J. Bailey

  • Localization of Drosophila retinal degeneration B, a membrane-associated phosphatidylinositol transfer protein

    Thomas S. Vihtelic;Mark Goebl;Scott Milligan;Joseph E. O'Tousa

  • Fgf-dependent depletion of microRNA-133 promotes appendage regeneration in zebrafish

    Viravuth P. Yin;J. Michael Thomson;Ryan Thummel;David R. Hyde

  • The Phosphatidylinositol Transfer Protein Domain of Drosophila Retinal Degeneration B Protein Is Essential for Photoreceptor Cell Survival and Recovery from Light Stimulation

    Scott C. Milligan;James G. Alb;Raya B. Elagina;Vytas A. Bankaitis

  • Ganglion cell regeneration following whole-retina destruction in zebrafish.

    Tshering Sherpa;Shane M. Fimbel;Dianne E. Mallory;Hans Maaswinkel

  • dgq: A drosophila gene encoding a visual system-specific Gα molecule

    Young Jae Lee;Matthew B. Dobbs;Mary L. Verardi;David R. Hyde

  • Genetic determinants of hyaloid and retinal vasculature in zebrafish

    Yolanda Alvarez;Maria L Cederlund;David C Cottell;Brent R Bill

  • Repressing notch signaling and expressing TNFα are sufficient to mimic retinal regeneration by inducing Müller glial proliferation to generate committed progenitor cells.

    Clay Conner;Kristin M. Ackerman;Manuela Lahne;Joshua S. Hobgood

  • CNTF induces photoreceptor neuroprotection and Müller glial cell proliferation through two different signaling pathways in the adult zebrafish retina.

    Sean C. Kassen;Ryan Thummel;Laura A. Campochiaro;Molly J. Harding

  • A novel model of retinal ablation demonstrates that the extent of rod cell death regulates the origin of the regenerated zebrafish rod photoreceptors

    Jacob E. Montgomery;Michael J. Parsons;David R. Hyde

  • Twenty Drosophila visual system cDNA clones: one is a homolog of human arrestin.

    David R. Hyde;Kirk L. Mecklenburg;John A. Pollock;Thomas S. Vihtelic

  • Isolation and characterization of the Drosophila retinal degeneration B (rdgB) gene.

    T S Vihtelic;D R Hyde;J E O'Tousa

  • Stat3 defines three populations of Müller glia and is required for initiating maximal müller glia proliferation in the regenerating zebrafish retina.

    Craig M. Nelson;Ryne A. Gorsuch;Travis J. Bailey;Kristin M. Ackerman

  • The drosophila dgq gene encodes a Gα protein that mediates phototransduction

    Young-Jae Lee;Seema Shah;Emiko Suzuki;Troy Zars

  • Regulation of Müller glial dependent neuronal regeneration in the damaged adult zebrafish retina.

    Ryne A. Gorsuch;David R. Hyde

Frequent Co-Authors

Andy J. Fischer
Andy J. Fischer The Ohio State University
Jiang Qian
Jiang Qian Johns Hopkins University School of Medicine
Kenneth D. Poss
Kenneth D. Poss Duke University
Seth Blackshaw
Seth Blackshaw Johns Hopkins University School of Medicine
Vytas A. Bankaitis
Vytas A. Bankaitis Texas A&M University
William R. Jeffery
William R. Jeffery University of Maryland, College Park
Graeme Wistow
Graeme Wistow National Institutes of Health
Baruch Minke
Baruch Minke Hebrew University of Jerusalem
Zvi Selinger
Zvi Selinger Hebrew University of Jerusalem
James G. Patton
James G. Patton Vanderbilt University

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