What is he best known for?
The fields of study he is best known for:
His primary areas of study are Virology, Antibody, Epitope, Virus and Neutralization. His work on Virology is being expanded to include thematically relevant topics such as Gp41. The various areas that James M. Binley examines in his Antibody study include Viral replication and Antigen.
His Epitope research includes elements of Molecular biology, Viral envelope and Monoclonal antibody. His Molecular biology research is multidisciplinary, relying on both Peptide sequence, Neutralizing antibody and Binding site. His study looks at the relationship between Virus and fields such as Glycoprotein, as well as how they intersect with chemical problems.
His most cited work include:
- CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5. (1013 citations)
- Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41. (759 citations)
- Comprehensive Cross-Clade Neutralization Analysis of a Panel of Anti-Human Immunodeficiency Virus Type 1 Monoclonal Antibodies (681 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of investigation include Virology, Antibody, Epitope, Molecular biology and Virus. The study incorporates disciplines such as Immunology, Gp41 and Monoclonal antibody in addition to Virology. His Antibody research incorporates themes from Recombinant DNA and Simian immunodeficiency virus.
His Epitope research is multidisciplinary, incorporating perspectives in Viral envelope and Glycoprotein. His research integrates issues of Plasma protein binding, Receptor, Peptide sequence, Protein structure and Binding site in his study of Molecular biology. His Virus study combines topics in areas such as Cell culture and Microbiology.
He most often published in these fields:
- Virology (83.65%)
- Antibody (58.65%)
- Epitope (49.04%)
What were the highlights of his more recent work (between 2014-2021)?
- Virology (83.65%)
- Epitope (49.04%)
- Antibody (58.65%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Virology, Epitope, Antibody, Binding site and Cell biology. His biological study deals with issues like Antigen, which deal with fields such as NOD mice. He interconnects Transcription, Neutralization, Glycoprotein and Effector in the investigation of issues within Epitope.
His Antibody research is mostly focused on the topic Monoclonal antibody. His studies deal with areas such as Neutralizing antibody and Glycan as well as Binding site. James M. Binley has researched Cell biology in several fields, including Innate immune system, Interactome, Viral replication and Calcium signaling.
Between 2014 and 2021, his most popular works were:
- Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env (234 citations)
- Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site (105 citations)
- Mapping polyclonal HIV-1 antibody responses via next-generation neutralization fingerprinting. (57 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Antibody
- Immune system
James M. Binley mainly investigates Epitope, Antibody, Virology, Monoclonal antibody and Antigen. His research in Antibody intersects with topics in Viral protein and Binding site. James M. Binley combines subjects such as Protein structure, Antigenicity, Stereochemistry and Ligand with his study of Viral protein.
His studies in Binding site integrate themes in fields like Neutralizing antibody and Glycan. James M. Binley merges many fields, such as Antigen and Trimer, in his writings. The concepts of his Polyclonal antibodies study are interwoven with issues in Antibody response, Serology and Neutralization.
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