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Jörg Stelling

Jörg Stelling

D-Index & Metrics

Engineering and Technology

D-Index
36
Citations
9278
World Ranking
8560
National Ranking
122

Overview

Jörg Stelling is affiliated with ETH Zurich in Switzerland and has contributed extensively to the field of biochemistry, genetics, and molecular biology. Their research spans several subfields including molecular biology, genetics, computational theory and mathematics, biotechnology, and hardware and architecture.

The main topics covered in their work include:

  • Gene Regulatory Network Analysis
  • CRISPR and Genetic Engineering
  • Microbial Metabolic Engineering and Bioproduction
  • Evolution and Genetic Dynamics
  • Bioinformatics and Genomic Networks
  • Computational Drug Discovery Methods
  • Metabolomics and Mass Spectrometry Studies

Their recent publications illustrate a focus on synthetic biology, bioinformatics, and system biology approaches, with notable papers such as:

  • <scp>SBML</scp> Level 3: an extensible format for the exchange and reuse of biological models (2020), published in Molecular Systems Biology
  • Multistable and dynamic CRISPRi-based synthetic circuits (2020), published in Nature Communications
  • Robustness and innovation in synthetic genotype networks (2023), published in Nature Communications
  • ENKIE: a package for predicting enzyme kinetic parameter values and their uncertainties (2024), published in Bioinformatics
  • Synthetic genotype networks (2022), published in bioRxiv (Cold Spring Harbor Laboratory)

Their frequent co-authors include Javier Santos-Moreno, Eve Tasiudi, Yolanda Schaerli, Hadiastri Kusumawardhani, and Hans-Michael Kaltenbach. These collaborations contribute to research published primarily in venues such as Nature Communications, bioRxiv (Cold Spring Harbor Laboratory), Molecular Systems Biology, Bioinformatics, and Cell Host & Microbe.

Jörg Stelling's body of work reflects a multidisciplinary approach combining experimental and computational methods, making contributions across various topics in genetic engineering, system biology, and enzyme kinetics prediction.

Best Publications

  • The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models.

    M. Hucka;A. Finney;H. M. Sauro;H. Bolouri;H. Bolouri

  • Robustness of cellular functions

    Jörg Stelling;Uwe Sauer;Zoltan Szallasi;Francis J. Doyle

  • Metabolic network structure determines key aspects of functionality and regulation

    Jörg Stelling;Steffen Klamt;Katja Bettenbrock;Stefan Schuster

  • A tunable synthetic mammalian oscillator

    Marcel Tigges;Tatiana T. Marquez-Lago;Tatiana T. Marquez-Lago;Jörg Stelling;Jörg Stelling;Martin Fussenegger

  • Microbial network disturbances in relapsing refractory Crohn's disease.

    Bahtiyar Yilmaz;Pascal Juillerat;Ove Øyås;Charlotte Ramon

  • Large-scale computation of elementary flux modes with bit pattern trees

    Marco Terzer;Jörg Stelling

  • Two approaches for metabolic pathway analysis

    Steffen Klamt;Jörg Stelling

  • Global Network Reorganization During Dynamic Adaptations of Bacillus subtilis Metabolism

    Joerg Martin Buescher;Wolfram Liebermeister;Matthieu Jules;Markus Uhr

  • Robustness properties of circadian clock architectures.

    Jörg Stelling;Ernst Dieter Gilles;Francis J. Doyle

  • Self-sufficient control of urate homeostasis in mice by a synthetic circuit

    Christian Kemmer;Marc Gitzinger;Marie Daoud-El Baba;Valentin Djonov

  • Combinatorial complexity of pathway analysis in metabolic networks.

    Steffen Klamt;Jörg Stelling

  • System Modeling in Cellular Biology: From Concepts to Nuts and Bolts

    Zoltan Szallasi;Jörg Stelling;Vipul Periwal

  • FluxAnalyzer: exploring structure, pathways, and flux distributions in metabolic networks on interactive flux maps.

    Steffen Klamt;Jörg Stelling;Martin Ginkel;Ernst Dieter Gilles

  • Mathematical models in microbial systems biology.

    Jörg Stelling

  • Ensemble modeling for analysis of cell signaling dynamics

    Lars Kuepfer;Matthias Peter;Uwe Sauer;Jörg Stelling

  • β-cell-mimetic designer cells provide closed-loop glycemic control.

    Mingqi Xie;Haifeng Ye;Hui Wang;Ghislaine Charpin-El Hamri

  • Genome-scale metabolic networks.

    Marco Terzer;Nathaniel D. Maynard;Markus W. Covert;Jörg Stelling

  • Computational design of synthetic gene circuits with composable parts

    M.A. Marchisio;J. Stelling

  • Subnetwork analysis reveals dynamic features of complex (bio)chemical networks

    Carsten Conradi;Dietrich Flockerzi;Jörg Raisch;Jörg Raisch;Jörg Stelling

  • Computational design tools for synthetic biology.

    Mario A Marchisio;Jörg Stelling

  • Synthetic two-way communication between mammalian cells.

    William Bacchus;Moritz Lang;Marie Daoud El-Baba;Wilfried Weber;Wilfried Weber

  • Automatic Design of Digital Synthetic Gene Circuits

    Mario A. Marchisio;Jörg Stelling

Frequent Co-Authors

Zoltan Szallasi
Zoltan Szallasi Boston Children's Hospital
Francis J. Doyle
Francis J. Doyle Brown University
Martin Fussenegger
Martin Fussenegger University of Basel
Uwe Sauer
Uwe Sauer ETH Zurich
Michel O. Steinmetz
Michel O. Steinmetz Paul Scherrer Institute
Steffen Klamt
Steffen Klamt Max Planck Institute for Dynamics of Complex Technical Systems
Ernst Dieter Gilles
Ernst Dieter Gilles Max Planck Society
Sebastien Gagneux
Sebastien Gagneux University of Basel
Yves Barral
Yves Barral ETH Zurich
Wilfried Weber
Wilfried Weber University of Freiburg

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