What is he best known for?
The fields of study John Groffen is best known for:
His Cell biology study in the realm of Transforming growth factor connects with subjects such as Anatomy and Mesenchyme.
His Cell biology study frequently draws connections to other fields, such as Signal transduction, Mesenchyme and Transforming growth factor.
In his research, he undertakes multidisciplinary study on Signal transduction and Tyrosine kinase.
His Tyrosine kinase study frequently links to adjacent areas such as Receptor.
His research brings together the fields of ABL and Receptor.
He is researching Chromosome as part of the investigation of Chromosome 22, Karyotype, Chromosome 9 and Breakpoint.
John Groffen performs multidisciplinary study on Chromosome 22 and Chromosome in his works.
John Groffen incorporates Karyotype and Chromosomal translocation in his studies.
His study ties his expertise on Breakpoint together with the subject of Chromosomal translocation.
His most cited work include:
- Identification of FAP Locus Genes from Chromosome 5q21 (2149 citations)
- Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22 (1534 citations)
- A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia (1284 citations)
What are the main themes of his work throughout his whole career to date
His work in Genetics is not limited to one particular discipline; it also encompasses Breakpoint.
His research on Breakpoint often connects related topics like Gene.
He integrates many fields, such as Gene and Molecular biology, in his works.
He undertakes multidisciplinary studies into Molecular biology and Genetics in his work.
His Cancer research study frequently intersects with other fields, such as Myeloid leukemia.
Much of his study explores Myeloid leukemia relationship to Cancer research.
Signal transduction is closely attributed to Biochemistry in his work.
His study deals with a combination of Biochemistry and Receptor.
His Receptor study frequently draws parallels with other fields, such as breakpoint cluster region.
John Groffen most often published in these fields:
- Genetics (65.82%)
- Gene (65.82%)
- Cancer research (41.77%)
What were the highlights of his more recent work (between 2013-2018)?
- Cancer research (100.00%)
- Immunology (80.00%)
- Genetics (60.00%)
In recent works John Groffen was focusing on the following fields of study:
Many of his studies on Cancer research apply to Stromal cell as well.
His Stromal cell study frequently draws parallels with other fields, such as Cancer research.
Many of his studies on Immunology involve topics that are commonly interrelated, such as Lymphoblastic Leukemia.
Lymphoblastic Leukemia is often connected to Immunology in his work.
His research on Genetics frequently links to adjacent areas such as Fibronectin.
While working in this field, John Groffen studies both Fibronectin and Extracellular matrix.
His research on Extracellular matrix often connects related topics like Cell biology.
Many of his studies involve connections with topics such as Stem cell and Cell biology.
Stem cell and Bone marrow are two areas of study in which he engages in interdisciplinary work.
Between 2013 and 2018, his most popular works were:
- B-cell precursor acute lymphoblastic leukemia and stromal cells communicate through Galectin-3 (73 citations)
- Effector-Mediated Eradication of Precursor B Acute Lymphoblastic Leukemia with a Novel Fc-Engineered Monoclonal Antibody Targeting the BAFF-R (31 citations)
- Treatment of B-cell precursor acute lymphoblastic leukemia with the Galectin-1 inhibitor PTX008 (28 citations)
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