His Cell biology study in the realm of Transforming growth factor connects with subjects such as Anatomy and Mesenchyme. His Cell biology study frequently draws connections to other fields, such as Signal transduction, Mesenchyme and Transforming growth factor. In his research, he undertakes multidisciplinary study on Signal transduction and Tyrosine kinase. His Tyrosine kinase study frequently links to adjacent areas such as Receptor. His research brings together the fields of ABL and Receptor. He is researching Chromosome as part of the investigation of Chromosome 22, Karyotype, Chromosome 9 and Breakpoint. John Groffen performs multidisciplinary study on Chromosome 22 and Chromosome in his works. John Groffen incorporates Karyotype and Chromosomal translocation in his studies. His study ties his expertise on Breakpoint together with the subject of Chromosomal translocation.
His work in Genetics is not limited to one particular discipline; it also encompasses Breakpoint. His research on Breakpoint often connects related topics like Gene. He integrates many fields, such as Gene and Molecular biology, in his works. He undertakes multidisciplinary studies into Molecular biology and Genetics in his work. His Cancer research study frequently intersects with other fields, such as Myeloid leukemia. Much of his study explores Myeloid leukemia relationship to Cancer research. Signal transduction is closely attributed to Biochemistry in his work. His study deals with a combination of Biochemistry and Receptor. His Receptor study frequently draws parallels with other fields, such as breakpoint cluster region.
Many of his studies on Cancer research apply to Stromal cell as well. His Stromal cell study frequently draws parallels with other fields, such as Cancer research. Many of his studies on Immunology involve topics that are commonly interrelated, such as Lymphoblastic Leukemia. Lymphoblastic Leukemia is often connected to Immunology in his work. His research on Genetics frequently links to adjacent areas such as Fibronectin. While working in this field, John Groffen studies both Fibronectin and Extracellular matrix. His research on Extracellular matrix often connects related topics like Cell biology. Many of his studies involve connections with topics such as Stem cell and Cell biology. Stem cell and Bone marrow are two areas of study in which he engages in interdisciplinary work.
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Identification of FAP locus genes from chromosome 5q21
Kenneth W. Kinzler;Mef C. Nilbert;Li Kuo Su;Bert Vogelstein.
Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22
Groffen J;Stephenson;Heisterkamp N;de Klein A.
A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia
Annelies de Klein;Ad Geurts van Kessel;Gerard Grosveld;Claus R. Bartram.
Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction.
Vesa Kaartinen;Jan Willem Voncken;Charles Shuler;David Warburton.
Nature Genetics (1995)
Structural organization of the bcr gene and its role in the Ph' translocation.
Heisterkamp N;Stam K;Groffen J;de Klein A.
Localization of the c- abl oncogene adjacent to a translocation break point in chronic myelocytic leukaemia
Nora Heisterkamp;John R. Stephenson;John Groffen;Pamela F. Hansen.
Translocation of c- abl oncogene correlates with the presence of a Philadelphia chromosome in chronic myelocytic leukaemia
Claus R. Bartram;Annelies de Klein;Anne Hagemeijer;Ton van Agthoven.
Acute leukaemia in bcr/abl transgenic mice
N Heisterkamp;G Jenster;J ten Hoeve;D Zovich.
A novel abl protein expressed in Philadelphia chromosome positive acute lymphoblastic leukaemia.
L C Chan;K K Karhi;S I Rayter;N Heisterkamp.
Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus
U R Rapp;M D Goldsborough;G E Mark;T I Bonner.
Proceedings of the National Academy of Sciences of the United States of America (1983)
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