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Biology and Biochemistry

D-Index
74
Citations
25215
World Ranking
5495
National Ranking
2610

Overview

Nora Heisterkamp is affiliated with Children's Hospital of Los Angeles in the United States. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology, focusing particularly on molecular biology, immunology, oncology, hematology, and public health aspects.

Heisterkamp's work predominantly addresses topics such as glycosylation and glycoproteins research, galectins and cancer biology, acute lymphoblastic leukemia research, peptidase inhibition and analysis, ubiquitin and proteasome pathways, chronic lymphocytic leukemia research, and acute myeloid leukemia research.

Recent significant publications authored or coauthored by Heisterkamp include:

  • CAR T-cells that target acute B-lineage leukemia irrespective of CD19 expression, 2020, Leukemia
  • Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia, 2020, Blood
  • Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer, 2021, Molecular Cell
  • Glycoproteome remodeling in MLL-rearranged B-cell precursor acute lymphoblastic leukemia, 2021, Theranostics
  • Novel Selective Galectin-3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia, 2022, Journal of Medicinal Chemistry

The frequent coauthors collaborating with Nora Heisterkamp include Hisham Abdel-Azim, Lu Yang, Mingfeng Zhang, Eun Ji Joo, and Chun-Wei Chen.

Heisterkamp's publications are often found in the journals Blood, bioRxiv (Cold Spring Harbor Laboratory), Leukemia, International Journal of Molecular Sciences, and Molecular Cell. The most common venues for their work are Blood and bioRxiv, highlighting a strong focus on hematology and related biomedical fields.

Best Publications

  • Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22

    Groffen J;Stephenson;Heisterkamp N;de Klein A

  • A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia

    Annelies de Klein;Ad Geurts van Kessel;Gerard Grosveld;Claus R. Bartram

  • Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction.

    Vesa Kaartinen;Jan Willem Voncken;Charles Shuler;David Warburton

  • Localization of the c- abl oncogene adjacent to a translocation break point in chronic myelocytic leukaemia

    Nora Heisterkamp;John R. Stephenson;John Groffen;Pamela F. Hansen

  • Translocation of c- abl oncogene correlates with the presence of a Philadelphia chromosome in chronic myelocytic leukaemia

    Claus R. Bartram;Annelies de Klein;Anne Hagemeijer;Ton van Agthoven

  • Acute leukaemia in bcr/abl transgenic mice

    N Heisterkamp;G Jenster;J ten Hoeve;D Zovich

  • A novel abl protein expressed in Philadelphia chromosome positive acute lymphoblastic leukaemia.

    L C Chan;K K Karhi;S I Rayter;N Heisterkamp

  • Unique fusion of bcr and c-abl genes in Philadelphia chromosome positive acute lymphoblastic leukemia

    André Hermans;Nora Heisterkamp;Marieke von Lindern;Sjozef van Baal

  • p120 Catenin-associated Fer and Fyn tyrosine kinases regulate β-catenin Tyr-142 phosphorylation and β-catenin-α-catenin interaction

    Jose Piedra;Jose Piedra;Susana Miravet;Julio Castaño;Héctor G. Pálmer

  • TGFβ signaling plays a critical role in promoting alternative macrophage activation

    Dapeng Gong;Wei Shi;Sun-ju Yi;Hui Chen

  • Chromosomal localization of human cellular homologues of two viral oncogenes.

    Nora Heisterkamp;John Groffen;John R. Stephenson;N. K. Spurr

  • Characterization of RAC3, a novel member of the Rho family

    Leena Haataja;John Groffen;Nora Heisterkamp

  • Evidence of a new chimeric bcr/c-abl mRNA in patients with chronic myelocytic leukemia and the Philadelphia chromosome.

    K Stam;N Heisterkamp;G Grosveld;A de Klein

  • BCR/ABL P210 and P190 cause distinct leukemia in transgenic mice

    Jan Willem Voncken;Vesa Kaartinen;Paul K. Pattengale;Wilfred T.V. Germeraad

  • Isolation and chromosomal localization of CRKL, a human crk-like gene.

    ten Hoeve J;Morris C;Heisterkamp N;Groffen J

  • TYROSINE PHOSPHORYLATION OF CRKL IN PHILADELPHIA+ LEUKEMIA

    J ten Hoeve;RB Arlinghaus;JQ Guo;N Heisterkamp

  • The chronic myelocytic cell line K562 contains a breakpoint in bcr and produces a chimeric bcr/c-abl transcript.

    G Grosveld;T Verwoerd;T van Agthoven;A de Klein

  • Increased neutrophil respiratory burst in bcr-null mutants

    Jan Willem Voncken;Hermien van Schaick;Vesa Kaartinen;Kathleen Deemer

  • Abr and Bcr are multifunctional regulators of the Rho GTP-binding protein family

    T H Chuang;X Xu;X Xu;V Kaartinen;N Heisterkamp

  • Transforming growth factor‐β3 regulates transdifferentiation of medial edge epithelium during palatal fusion and associated degradation of the basement membrane

    Vesa Kaartinen;Xiao Mei Cui;Nora Heisterkamp;John Groffen

Frequent Co-Authors

John Groffen
John Groffen Children's Hospital of Los Angeles
Vesa Kaartinen
Vesa Kaartinen University of Michigan–Ann Arbor
Markus Müschen
Markus Müschen Yale University
John R. Stephenson
John R. Stephenson National Institutes of Health
Gerard Grosveld
Gerard Grosveld St. Jude Children's Research Hospital
Paul K. Pattengale
Paul K. Pattengale University of Southern California
Hassan Jumaa
Hassan Jumaa Max Planck Society
Annelies de Klein
Annelies de Klein Erasmus University Rotterdam
Claus R. Bartram
Claus R. Bartram Heidelberg University

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