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Neuroscience

D-Index
36
Citations
4960
World Ranking
9032
National Ranking
3816

Overview

Claudia A. Grillo is affiliated with the University of South Carolina in the United States and has contributed extensively to the fields of neuroscience and medicine. Their research primarily focuses on areas including regulation of appetite and obesity, adipose tissue and metabolism, and the mechanisms underlying neuroinflammation and neurodegeneration.

Their recent publications cover topics such as the impact of diet on brain function, behavioral effects of insulin resistance, and the influence of cholinergic pathways in neuroinflammation. Notable papers include:

  • High-fat diet induces neuroinflammation and reduces the serotonergic response to escitalopram in the hippocampus of obese rats (2021, Brain Behavior and Immunity)
  • Hippocampal-specific insulin resistance elicits behavioral despair and hippocampal dendritic atrophy (2021, Neurobiology of Stress)
  • Pyridostigmine bromide elicits progressive and chronic impairments in the cholinergic anti-inflammatory pathway in the prefrontal cortex and hippocampus of male rats (2022, Neurobiology of Stress)
  • Differential effects of high-fat diet on endocrine, metabolic and depressive-like behaviors in male and female rats (2024, Appetite)
  • Voluntary wheel running as a promising strategy to promote autonomic resilience to social stress in females: Vagal tone lies at the heart of the matter (2024, Autonomic Neuroscience)

Their work spans several important subfields of study such as endocrine and autonomic systems, physiology, neurology, nutrition and dietetics, and molecular biology. These areas support their focus on the biochemical and physiological pathways influencing metabolic and neurological health.

Frequent co-authors collaborating with Claudia A. Grillo include Lawrence P. Reagan, J.L. Woodruff, Nicholas Maxwell, Alia T. Sadek, and Jim R. Fadel. This reflects a multidisciplinary approach crossing various aspects of neuroscience and medicine.

Their research has been published repeatedly in several scientific journals, with common publication venues being:

  • Brain Behavior and Immunity
  • Neurobiology of Stress
  • Journal of Neurochemistry
  • Alzheimer's & Dementia
  • Appetite

Overall, their scientific contributions provide insights into the complex interactions between diet, metabolism, and brain function, with a detailed emphasis on neuroinflammation, stress responses, and receptor-level signaling pathways. Their multidisciplinary research integrates molecular biology techniques with physiological studies to explore how systemic and neurological factors contribute to health and disease.

Best Publications

  • Memory impairment in obese Zucker rats: an investigation of cognitive function in an animal model of insulin resistance and obesity.

    Gordon Winocur;Carol E. Greenwood;Gerardo G. Piroli;Claudia A. Grillo

  • Hippocampal Insulin Resistance Impairs Spatial Learning and Synaptic Plasticity

    Claudia A. Grillo;Gerardo G. Piroli;Robert C. Lawrence;Shayna A. Wrighten

  • Acute stress-mediated increases in extracellular glutamate levels in the rat amygdala: differential effects of antidepressant treatment.

    Leah R. Reznikov;Claudia A. Grillo;Gerardo G. Piroli;Ravi K. Pasumarthi

  • Insulin-stimulated translocation of GLUT4 to the plasma membrane in rat hippocampus is PI3-kinase dependent.

    C.A. Grillo;G.G. Piroli;R.M. Hendry;L.P. Reagan

  • A look inside the diabetic brain: Contributors to diabetes-induced brain aging

    Shayna A. Wrighten;Gerardo G. Piroli;Claudia A. Grillo;Lawrence P. Reagan

  • Corticosterone Impairs Insulin-Stimulated Translocation of GLUT4 in the Rat Hippocampus

    Gerardo G. Piroli;Claudia A. Grillo;Leah R. Reznikov;Sheila Adams

  • The As and Ds of stress: metabolic, morphological and behavioral consequences.

    Lawrence P. Reagan;Claudia A. Grillo;Gerado G. Piroli

  • Localization and regulation of GLUTx1 glucose transporter in the hippocampus of streptozotocin diabetic rats.

    Lawrence P. Reagan;Naira Gorovits;Elena K. Hoskin;Stephen E. Alves

  • Immunocytochemical analysis of synaptic proteins provides new insights into diabetes-mediated plasticity in the rat hippocampus

    C.A. Grillo;G.G. Piroli;G.G. Piroli;G.E. Wood;L.R. Reznikov

  • Peripheral glucose administration stimulates the translocation of GLUT8 glucose transporter to the endoplasmic reticulum in the rat hippocampus.

    Gerardo G. Piroli;Claudia A. Grillo;Elena K. Hoskin;Vladimir Znamensky;Vladimir Znamensky

  • Downregulation of hypothalamic insulin receptor expression elicits depressive-like behaviors in rats

    Claudia A. Grillo;Gerardo G. Piroli;Kris F. Kaigler;Steven P. Wilson

  • Intranasal insulin in Alzheimer's disease: Food for thought.

    Colin D. Chapman;Helgi B. Schiöth;Claudia A. Grillo;Christian Benedict

  • Leptin resistance and hippocampal behavioral deficits.

    Catherine Van Doorn;Victoria A. Macht;Claudia A. Grillo;Lawrence P. Reagan;Lawrence P. Reagan

  • Region specific increases in oxidative stress and superoxide dismutase in the hippocampus of diabetic rats subjected to stress.

    C.A Grillo;G.G Piroli;D.R Rosell;E.K Hoskin

  • Insulin Resistance as a Therapeutic Target in the Treatment of Alzheimer's Disease: A State-of-the-Art Review.

    Christian Benedict;Claudia A. Grillo

  • Tianeptine increases brain-derived neurotrophic factor expression in the rat amygdala

    Lawrence P. Reagan;Robert M. Hendry;Leah R. Reznikov;Gerardo G. Piroli

  • Stress as a one-armed bandit: Differential effects of stress paradigms on the morphology, neurochemistry and behavior in the rodent amygdala.

    Marlene A. Wilson;Claudia A. Grillo;Jim R. Fadel;Lawrence P. Reagan

  • Lentivirus-mediated downregulation of hypothalamic insulin receptor expression.

    C.A. Grillo;K.L. Tamashiro;G.G. Piroli;S. Melhorn

  • Obesity/hyperleptinemic phenotype impairs structural and functional plasticity in the rat hippocampus.

    Claudia A. Grillo;Gerardo G. Piroli;Lorain Junor;Steven P. Wilson

  • Regulation of gene expression by corticoid hormones in the brain and spinal cord.

    Alejandro F. De Nicola;Alejandro F. De Nicola;Monica Ferrini;Susana L. Gonzalez;Susana L. Gonzalez;Maria Claudia Gonzalez Deniselle;Maria Claudia Gonzalez Deniselle

  • Insulin resistance and hippocampal dysfunction: Disentangling peripheral and brain causes from consequences.

    Claudia A. Grillo;Jennifer L. Woodruff;Victoria A. Macht;Lawrence P. Reagan;Lawrence P. Reagan

Frequent Co-Authors

Lawrence P. Reagan
Lawrence P. Reagan University of South Carolina
Bruce S. McEwen
Bruce S. McEwen Rockefeller University
Alejandro F. De Nicola
Alejandro F. De Nicola University of Buenos Aires
Jim R. Fadel
Jim R. Fadel University of South Carolina
Marlene A. Wilson
Marlene A. Wilson University of South Carolina
Steven P. Wilson
Steven P. Wilson University of South Carolina
Randall R. Sakai
Randall R. Sakai University of Cincinnati
Jeffrey D. Rothstein
Jeffrey D. Rothstein Johns Hopkins University
Robert G. Struble
Robert G. Struble Southern Illinois University School of Medicine
Dean E. Dluzen
Dean E. Dluzen John A. Logan College

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