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Themis R. Kyriakides

Themis R. Kyriakides

D-Index & Metrics

Biology and Biochemistry

D-Index
68
Citations
13155
World Ranking
7964
National Ranking
3605

Research.com Recognitions

  • 2020 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

Themis R. Kyriakides is affiliated with Yale University in the United States and specializes in research within the field of Medicine. Their work spans several subfields including Surgery, Biomedical Engineering, Biomaterials, Rehabilitation, and Molecular Biology. The research topics addressed focus on Tissue Engineering and Regenerative Medicine, Electrospun Nanofibers in Biomedical Applications, Wound Healing and Treatments, 3D Printing in Biomedical Research, Bone Tissue Engineering Materials, Cell Adhesion Molecules Research, and Orthopedic Infections and Treatments.

Themis R. Kyriakides has contributed to several recent publications, including:

  • Biocompatibility of nanomaterials and their immunological properties (2021), Biomedical Materials
  • The role of extracellular matrix in the pathophysiology of diabetic wounds (2020), Matrix Biology Plus
  • Glycocalyx-Like Hydrogel Coatings for Small Diameter Vascular Grafts (2020), Advanced Functional Materials
  • Foreign body response to synthetic polymer biomaterials and the role of adaptive immunity (2022), Biomedical Materials
  • Dual therapeutic targeting of intra-articular inflammation and intracellular bacteria enhances chondroprotection in septic arthritis (2021), Science Advances

Themis R. Kyriakides frequently publishes in venues such as:

  • Biomedical Materials
  • Advanced Functional Materials
  • Scientific Reports
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Tissue Engineering Part A

Collaboration is evident in their work, with frequent coauthors including Hao Xing, Yaqing Huang, Henry C. Hsia, Laura G. Bracaglia, and Hyuk-Kwon Kwon.

Among Themis R. Kyriakides' recognitions is the award of Fellow of the Indian National Academy of Engineering (INAE) in 2020.

Best Publications

  • Tissue-engineered vascular grafts transform into mature blood vessels via an inflammation-mediated process of vascular remodeling

    Jason D. Roh;Rajendra Sawh-Martinez;Matthew P. Brennan;Steven M. Jay

  • Mice that lack thrombospondin 2 display connective tissue abnormalities that are associated with disordered collagen fibrillogenesis, an increased vascular density, and a bleeding diathesis.

    Themis R. Kyriakides;Yu Hong Zhu;Lynne T. Smith;Steven D. Bain

  • Bulk metallic glasses for biomedical applications

    Jan Schroers;Golden Kumar;Thomas M. Hodges;Stephen Chan

  • The lack of thrombospondin-1 (TSP1) dictates the course of wound healing in double-TSP1/TSP2-null mice.

    Azin Agah;Themis R. Kyriakides;Jack Lawler;Paul Bornstein

  • A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 and S phase.

    Nisar P. Malek;Holly Sundberg;Holly Sundberg;Seth McGrew;Keiko Nakayama

  • pH-sensitive polymers that enhance intracellular drug delivery in vivo.

    Themis R Kyriakides;Charles Y Cheung;Niren Murthy;Paul Bornstein

  • The role of thrombospondins 1 and 2 in the regulation of cell-matrix interactions, collagen fibril formation, and the response to injury.

    Paul Bornstein;Azin Agah;Themis R. Kyriakides

  • The CC Chemokine Ligand, CCL2/MCP1, Participates in Macrophage Fusion and Foreign Body Giant Cell Formation

    Themis R. Kyriakides;Matt J. Foster;Grant E. Keeney;Annabel Tsai

  • Extracellular matrix-derived biomaterials in engineering cell function.

    Hao Xing;Hudson Lee;Lijing Luo;Themis R. Kyriakides

  • A critical role for macrophages in neovessel formation and the development of stenosis in tissue-engineered vascular grafts

    Narutoshi Hibino;Tai Yi;Daniel R. Duncan;Animesh Rathore

  • Cell interactions with polymers

    W. Mark Saltzman;Themis R. Kyriakides

  • Small-diameter biodegradable scaffolds for functional vascular tissue engineering in the mouse model

    Jason D. Roh;Gregory N. Nelson;Matthew P. Brennan;Tamar L. Mirensky

  • Characterization of the in vitro macrophage response and in vivo host response to poly(ethylene glycol)-based hydrogels.

    Aaron D. Lynn;Themis R. Kyriakides;Stephanie J. Bryant

  • Thrombospondin 2, a matricellular protein with diverse functions.

    Paul Bornstein;Lucas C. Armstrong;Kurt D. Hankenson;Themis R. Kyriakides

  • Accelerated wound healing in mice with a disruption of the thrombospondin 2 gene.

    Themis R. Kyriakides;Jessica W.Y. Tam;Paul Bornstein

  • Matricellular proteins as modulators of cell-matrix interactions: adhesive defect in thrombospondin 2-null fibroblasts is a consequence of increased levels of matrix metalloproteinase-2.

    Zhantao Yang;Themis R. Kyriakides;Paul Bornstein

  • Mice that lack the angiogenesis inhibitor, thrombospondin 2, mount an altered foreign body reaction characterized by increased vascularity

    Themis R. Kyriakides;Kathleen J. Leach;Allan S. Hoffman;Buddy D. Ratner

  • Thrombospondin-2 plays a protective role in multistep carcinogenesis: a novel host anti-tumor defense mechanism.

    Thomas Hawighorst;Paula Velasco;Michael Streit;Young‐Kwon Hong

  • Mice that lack matrix metalloproteinase-9 display delayed wound healing associated with delayed reepithelization and disordered collagen fibrillogenesis.

    Themis R. Kyriakides;Drausin Wulsin;Eleni A. Skokos;Philip Fleckman

  • Matricellular proteins as modulators of wound healing and the foreign body response.

    Themis R. Kyriakides;Paul Bornstein

Frequent Co-Authors

Paul Bornstein
Paul Bornstein University of Washington
William C. Sessa
William C. Sessa Pfizer (United States)
Jan Schroers
Jan Schroers Yale University
W. Mark Saltzman
W. Mark Saltzman Yale University
Jun Yu
Jun Yu Chinese University of Hong Kong
Jordan S. Pober
Jordan S. Pober Yale University
Stephanie J. Bryant
Stephanie J. Bryant University of Colorado Boulder
Kurt D. Hankenson
Kurt D. Hankenson University of Michigan–Ann Arbor
Allan S. Hoffman
Allan S. Hoffman University of Washington
Michael Simons
Michael Simons Yale University

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