World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
15173
World Ranking
14228
National Ranking
1114

Overview

Andrea Pellagatti is affiliated with the University of Oxford in the United Kingdom. Their research spans across multiple disciplines, primarily within medicine and biochemistry, genetics, and molecular biology.

The scientist has contributed extensively to the fields of hematology, molecular biology, genetics, immunology, and cancer research. Their main research topics include acute myeloid leukemia research, RNA research and splicing, myeloproliferative neoplasms diagnosis and treatment, blood disorders and treatments, RNA modifications and cancer, epigenetics and DNA methylation, and protein degradation and inhibitors.

Andrea Pellagatti has a strong publication record in several journals, among which the most frequent include:

  • Blood
  • Advances in Biological Regulation
  • Nature Medicine
  • eLife
  • bioRxiv (Cold Spring Harbor Laboratory)

Their recent papers exemplify ongoing research interests and contributions, including the following:

  • "Molecular International Prognostic Scoring System for Myelodysplastic Syndromes" (2022), published in NEJM Evidence
  • "Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes" (2020), published in Nature Medicine
  • "SF3B1-mutant MDS as a distinct disease subtype: a proposal from the International Working Group for the Prognosis of MDS" (2020), published in Blood
  • "SF3B1 mutations induce R-loop accumulation and DNA damage in MDS and leukemia cells with therapeutic implications" (2020), published in Leukemia
  • "Activation of targetable inflammatory immune signaling is seen in myelodysplastic syndromes with SF3B1 mutations" (2022), published in eLife

Collaborations appear to be an integral part of their research. Frequent co-authors include:

  • Jacqueline Boultwood
  • Matilde Y. Follo
  • Carlo Finelli
  • Pierre Fenaux
  • Peter L. Greenberg

Best Publications

  • Clinical and biological implications of driver mutations in myelodysplastic syndromes.

    Elli Papaemmanuil;Moritz Gerstung;Luca Malcovati;Sudhir Tauro

  • Somatic SF3B1 Mutation in Myelodysplasia with Ring Sideroblasts

    E. Papaemmanuil;M. Cazzola;J. Boultwood;L. Malcovati

  • Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes

    Elsa Bernard;Yasuhito Nannya;Robert P. Hasserjian;Sean M. Devlin

  • Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

    Y S Ju;L B Alexandrov;M Gerstung;I Martincorena

  • Myelodysplastic Syndromes Are Propagated by Rare and Distinct Human Cancer Stem Cells In Vivo

    Petter S. Woll;Una Kjällquist;Onima Chowdhury;Helen Doolittle

  • Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q− syndrome patients

    Andrea Pellagatti;Martin Jädersten;Ann-Mari Forsblom;Helen Cattan

  • Deregulated gene expression pathways in myelodysplastic syndrome hematopoietic stem cells

    A Pellagatti;M Cazzola;A Giagounidis;J Perry

  • Frequent mutation of the polycomb-associated gene ASXL1 in the myelodysplastic syndromes and in acute myeloid leukemia.

    J Boultwood;J Perry;A Pellagatti;M Fernandez-Mercado

  • Gene expression profiles of CD34+ cells in myelodysplastic syndromes: involvement of interferon-stimulated genes and correlation to FAB subtype and karyotype.

    Andrea Pellagatti;Mario Cazzola;Aristoteles A N Giagounidis;Luca Malcovati

  • Combining gene mutation with gene expression data improves outcome prediction in myelodysplastic syndromes

    Moritz Gerstung;Andrea Pellagatti;Luca Malcovati;Aristoteles Giagounidis

  • Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations.

    Britta Will;Li Zhou;Thomas O. Vogler;Susanna Ben-Neriah

  • Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations

    Andrea Pellagatti;Richard N. Armstrong;Violetta Steeples;Eshita Sharma

  • TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups

    Detlef Haase;Kristen E Stevenson;Donna Neuberg;Jaroslaw P Maciejewski

  • SF3B1-mutant MDS as a distinct disease subtype: a proposal from the International Working Group for the Prognosis of MDS

    Luca Malcovati;Kristen Stevenson;Elli Papaemmanuil;Donna Neuberg

  • Overexpression of IL-1 receptor accessory protein in stem and progenitor cells and outcome correlation in AML and MDS.

    Laura Barreyro;Britta Will;Boris Bartholdy;Li Zhou

  • Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells

    H. Dolatshad;A. Pellagatti;M. Fernandez-Mercado;B. H. Yip

  • U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies.

    Molly A. Smith;Molly A. Smith;Gaurav S. Choudhary;Andrea Pellagatti;Kwangmin Choi

  • Gene expression profiling of CD34+ cells in patients with the 5q- syndrome.

    Jacqueline Boultwood;Andrea Pellagatti;Helen Cattan;Charles H. Lawrie

  • Inhibition of the TGF-β receptor I kinase promotes hematopoiesis in MDS

    Li Zhou;Aaron N. Nguyen;Davendra Sohal;Jing Ying Ma

  • IL8-CXCR2 pathway inhibition as a therapeutic strategy against MDS and AML stem cells

    Carolina Schinke;Orsolya Giricz;Weijuan Li;Aditi Shastri

Frequent Co-Authors

Eva Hellström-Lindberg
Eva Hellström-Lindberg Karolinska University Hospital
Amit Verma
Amit Verma Albert Einstein College of Medicine
Mario Cazzola
Mario Cazzola University of Pavia
Ulrich Steidl
Ulrich Steidl Albert Einstein College of Medicine
Peter J. Campbell
Peter J. Campbell Wellcome Sanger Institute
Alan F. List
Alan F. List Precision BioSciences
Paresh Vyas
Paresh Vyas University of Oxford
Seishi Ogawa
Seishi Ogawa Kyoto University
Amittha Wickrema
Amittha Wickrema University of Chicago
Elli Papaemmanuil
Elli Papaemmanuil Memorial Sloan Kettering Cancer Center

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Pursuing a degree in Biology or Biochemistry opens the door to a wide range of rewarding careers, and online education has made specialized pathways more accessible than ever. Students interested in health and nutrition may explore options like an accelerated nutrition degree online, which can fast-track their education and entry into the workforce.

For those already in nursing, advancing from RN to BSN can enhance skills and job prospects. RN to BSN online programs offer flexibility and support for working professionals. If you're considering leadership or administrative roles in healthcare, a fast online master's in healthcare management can jumpstart your journey.

For a career focused on mental health, online PMHNP programs train advanced practice nurses to support patients’ mental well-being. Online degrees provide versatility, making it easier than ever to customize your studies and career path within the health and science sectors.

Best Scientists Citing Andrea Pellagatti

Trending Scientists