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Molecular Biology

D-Index
45
Citations
7126
World Ranking
2868
National Ranking
53

Overview

Adrian B. Hehl is affiliated with the University of Zurich in Switzerland and specializes in research primarily within the fields of immunology and microbiology, medicine, and biochemistry, genetics, and molecular biology. Their work extensively covers parasitology, epidemiology, molecular biology, virology, and cell biology.

Their academic contributions focus notably on studies related to Toxoplasma gondii, with additional research encompassing parasitic infections and diagnostics, herpesvirus infections and treatments, cytomegalovirus and herpesvirus research, protist diversity and phylogeny, bacteriophages and microbial interactions, and CRISPR and genetic engineering.

Recent publications by Adrian B. Hehl include the following papers:

  • Functional and Computational Genomics Reveal Unprecedented Flexibility in Stage-Specific Toxoplasma Metabolism, 2020, Cell Host & Microbe
  • In vitro production of cat-restricted Toxoplasma pre-sexual stages, 2023, Nature
  • Structural insights into an atypical secretory pathway kinase crucial for Toxoplasma gondii invasion, 2021, Nature Communications
  • Phosphoinositide-binding proteins mark, shape and functionally modulate highly-diverged endocytic compartments in the parasitic protist Giardia lamblia, 2020, PLoS Pathogens
  • In vitro production of cat-restricted Toxoplasma pre-sexual stages by epigenetic reprogramming, 2023, bioRxiv (Cold Spring Harbor Laboratory)

Frequent co-authors collaborating with Adrian B. Hehl include:

  • Chandra Ramakrishnan
  • Carmen Faso
  • Dominique Soldati-Favre
  • Rui Santos
  • Shweta V. Pipaliya

Their research is frequently published in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • BMC Biology
  • PLoS Pathogens
  • Cell Host & Microbe
  • Nature

Best Publications

  • Genomic minimalism in the early diverging intestinal parasite Giardia lamblia.

    Hilary G. Morrison;Andrew G. McArthur;Frances D. Gillin;Stephen B. Aley

  • Success and virulence in Toxoplasma as the result of sexual recombination between two distinct ancestries.

    Michael E. Grigg;Serge Bonnefoy;Adrian B. Hehl;Yasuhiro Suzuki;Yasuhiro Suzuki

  • Gene discovery by EST sequencing in Toxoplasma gondii reveals sequences restricted to the Apicomplexa.

    James W. Ajioka;John C. Boothroyd;Brian P. Brunk;Adrian Hehl

  • The Surface of Toxoplasma Tachyzoites Is Dominated by a Family of Glycosylphosphatidylinositol-Anchored Antigens Related to SAG1

    Ian D. Manger;Adrian B. Hehl;John C. Boothroyd

  • Toxoplasma gondii homologue of Plasmodium apical membrane antigen 1 is involved in invasion of host cells.

    Adrian B. Hehl;Adrian B. Hehl;Christine Lekutis;Michael E. Grigg;Peter J. Bradley

  • Release of metabolic enzymes by Giardia in response to interaction with intestinal epithelial cells.

    Emma Ringqvist;J.E. Daniel Palm;J.E. Daniel Palm;Hanna Skarin;Adrian B. Hehl

  • Expressed sequence tag analysis of the bradyzoite stage of Toxoplasma gondii: identification of developmentally regulated genes.

    Ian D. Manger;Adrian Hehl;Steve Parmley;L. David Sibley

  • A conserved stem-loop structure in the 3' untranslated region of procyclin mRNAs regulates expression in Trypanosoma brucei

    Adrian Hehl;Erik Vassella;Richard Braun;Isabel Roditi

  • Protein import, replication, and inheritance of a vestigial mitochondrion.

    Attila Regoes;Danai Zourmpanou;Gloria León-Avila;Mark van der Giezen

  • The surface of Toxoplasma: more and less.

    John C. Boothroyd;Adrian Hehl;Laura J. Knoll;Ian D. Manger

  • Genetic and biochemical analysis of development in Toxoplasma gondii

    John C. Boothroyd;Michael Black;Serge Bonnefoy;Adrian Hehl

  • RNA Seq analysis of the Eimeria tenella gametocyte transcriptome reveals clues about the molecular basis for sexual reproduction and oocyst biogenesis

    Robert A Walker;Robert A Walker;Philippa A Sharman;Catherine M Miller;Christoph Lippuner

  • An Ancestral Secretory Apparatus in the Protozoan Parasite Giardia intestinalis

    Matthias Marti;Attila Regös;Yajie Li;Elisabeth M. Schraner

  • Deoxysphingolipids, Novel Biomarkers for Type 2 Diabetes, Are Cytotoxic for Insulin-Producing Cells

    Richard A. Zuellig;Thorsten Hornemann;Alaa Othman;Adrian B. Hehl

  • Accurate polyadenylation of procyclin mRNAs in Trypanosoma brucei is determined by pyrimidine-rich elements in the intergenic regions

    N Schürch;A Hehl;E Vassella;R Braun

  • Asexual expansion of Toxoplasma gondii merozoites is distinct from tachyzoites and entails expression of non-overlapping gene families to attach, invade, and replicate within feline enterocytes

    Adrian B Hehl;Walter U Basso;Christoph Lippuner;Christoph Lippuner;Chandra Ramakrishnan

  • Stage-specific expression and targeting of cyst wall protein-green fluorescent protein chimeras in Giardia.

    Adrian B. Hehl;Matthias Marti;Peter Köhler

  • A druggable secretory protein maturase of Toxoplasma essential for invasion and egress.

    Sunil Kumar Dogga;Budhaditya Mukherjee;Damien Jacot;Tobias Kockmann

  • The Single Dynamin Family Protein in the Primitive Protozoan Giardia lamblia Is Essential for Stage Conversion and Endocytic Transport

    Verena Gaechter;Elisabeth Schraner;Peter Wild;Adrian B. Hehl

  • Ablation of the single dynamin of T. brucei blocks mitochondrial fission and endocytosis and leads to a precise cytokinesis arrest

    Anne-Laure Chanez;Adrian B. Hehl;Markus Engstler;André Schneider

Frequent Co-Authors

John C. Boothroyd
John C. Boothroyd Stanford University
Peter Deplazes
Peter Deplazes University of Zurich
Staffan G. Svärd
Staffan G. Svärd Uppsala University
Matthias Marti
Matthias Marti University of Glasgow
Michael E. Grigg
Michael E. Grigg National Institutes of Health
Joel B. Dacks
Joel B. Dacks University of Alberta
Norbert Müller
Norbert Müller University of Bern
Andrew Hemphill
Andrew Hemphill University of Bern
Dominique Soldati-Favre
Dominique Soldati-Favre University of Geneva
Isabel Roditi
Isabel Roditi University of Bern

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