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Warren J. Strittmatter

Warren J. Strittmatter

D-Index & Metrics

Biology and Biochemistry

D-Index
70
Citations
44433
World Ranking
6835
National Ranking
3151

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Warren J. Strittmatter is affiliated with Duke University in the United States. Their research primarily focuses on topics related to Alzheimer's disease and associated areas within medicine.

They have contributed to the following recent publications:

  • The PIONEER Study: A multi-center, randomized, double-blind, placebo-controlled phase 2 trial of the effects of T3D-959 on safety, cognition, function and plasma biomarkers in mild to moderate Alzheimer's disease subjects: Rationale and study design (2020), published in Alzheimer s & Dementia
  • Phase 2 PIONEER Trial of Oral T3D-959 for the Treatment of Patients Diagnosed with Mild-to-Moderate Alzheimer's Disease: New Results in a Modified Intent-to-Treat Population (2024), published in Alzheimer s & Dementia
  • Towards a more representative Alzheimer's disease clinical trial: Ethnic differences in underlying pathology call for demographic consideration in drug label development (2022), published in Alzheimer s & Dementia
  • The PIONEER Study: A Multi-center, Randomized, Double-blind, Placebo-controlled Phase 2 Trial of the Effects of T3D-959 on Safety, Cognition, Function and Plasma Biomarkers in Mild to Moderate Alzheimer's Disease Subjects: Study Update (2022), published in Alzheimer s & Dementia

The frequent coauthors working with Strittmatter include:

  • John Didsbury
  • Stan Chamberlain
  • Hoda Gabriel
  • Jessica Stanek
  • Blake Swearingen

Their research contributions have appeared mainly in the journal Alzheimer s & Dementia.

Strittmatter's fields of study encompass medicine, with extensions into several subfields including molecular biology, biological psychiatry, surgery, public health, environmental and occupational health, as well as economics and econometrics.

The topics covered in their work include:

  • Peroxisome Proliferator-Activated Receptors
  • Tryptophan and brain disorders
  • Lipoproteins and Cardiovascular Health
  • Ethics in Clinical Research
  • Health Systems, Economic Evaluations, Quality of Life
  • Statistical Methods in Clinical Trials
  • Alzheimer's disease research and treatments

Recognition for Strittmatter's work includes membership in the Association of American Physicians.

Best Publications

  • Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

    E. H. Corder;A. M. Saunders;W. J. Strittmatter;D. E. Schmechel

  • Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.

    Warren J. Strittmatter;Ann M. Saunders;Donald Schmechel;Margaret Pericak-Vance

  • Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease.

    A. M. Saunders;W. J. Strittmatter;D. Schmechel;P. H. St. George-Hyslop

  • Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease.

    Corder Eh;Saunders Am;Risch Nj;Strittmatter Wj

  • Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

    D E Schmechel;A M Saunders;W J Strittmatter;B J Crain

  • Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

    Warren J. Strittmatter;Karl H. Weisgraber;David Y. Huang;Li Ming Dong

  • Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines

    Alexander V. Panov;Claire-Anne Gutekunst;Blair R. Leavitt;Michael R. Hayden

  • Apolipoprotein E and Alzheimer disease

    Warren J. Strittmatter;Allen D. Roses

  • Apolipoprotein E ∈4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases

    A. M. Saunders;A. D. Roses;M. A. Pericak-Vance;K. C. Dole

  • Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease

    Warren J. Strittmatter;Ann M. Saunders;Michel Goedert;Karl H. Weisgraber

  • Apolipoprotein E and Alzheimer's disease

    Warren J. Strittmatter;Allen D. Roses

  • Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH.

    James R. Burke;Jan J. Enghild;Margaret E. Martin;Yuh Shan Jou

  • Hypothesis: Microtubule Instability and Paired Helical Filament Formation in the Alzheimer Disease Brain Are Related to Apolipoprotein E Genotype

    Warren J. Strittmatter;Karl H. Weisgraber;Michel Goedert;Ann M. Saunders

  • A genome-wide investigation of SNPs and CNVs in schizophrenia

    Anna C. Need;Dongliang Ge;Michael E. Weale;Jessica Maia

  • Transthyretin sequesters amyloid beta protein and prevents amyloid formation

    A L Schwarzman;L Gregori;M P Vitek;S Lyubski

  • beta-Adrenergic receptor agonists increase phospholipid methylation, membrane fluidity, and beta-adrenergic receptor-adenylate cyclase coupling

    Fusao Hirata;Warren J. Strittmatter;Julius Axelrod

  • ApoE genotype and survival from intracerebral haemorrhage

    MarkJ. Alberts;Carmen Graffagnino;Cheryl McClenny;David DeLong

  • Preliminary Report of a Genetic Basis for Cognitive Decline After Cardiac Operations

    B. E. Tardiff;M. F. Newman;A. M. Saunders;W. J. Strittmatter

  • Specificity, sensitivity, and predictive value of apolipoprotein-E genotyping for sporadic Alzheimer's disease

    A. M. Saunders;C. Hulette;K. A. Welsh-Bohmer;D. E. Schmechel

  • Apolipoprotein E is localized to the cytoplasm of human cortical neurons: a light and electron microscopic study.

    Seol Heui Han;Gillian Einstein;Karl H. Weisgraber;Warren J. Strittmatter

Frequent Co-Authors

Allen D. Roses
Allen D. Roses Duke University
Ann M. Saunders
Ann M. Saunders Durham University
James R. Burke
James R. Burke Duke University
Margaret A. Pericak-Vance
Margaret A. Pericak-Vance University of Miami
Jan J. Enghild
Jan J. Enghild Aarhus University
Guy S. Salvesen
Guy S. Salvesen Sanford Burnham Prebys Medical Discovery Institute
Karl H. Weisgraber
Karl H. Weisgraber University of California, San Francisco
Fusao Hirata
Fusao Hirata Johns Hopkins University
Osamu Onodera
Osamu Onodera Niigata University
Christine M. Hulette
Christine M. Hulette Duke University

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