What is he best known for?
The fields of study he is best known for:
Karl H. Weisgraber mainly focuses on Apolipoprotein E, Biochemistry, Apolipoprotein B, Lipoprotein and Endocrinology.
His Apolipoprotein E study incorporates themes from LDL receptor, Very low-density lipoprotein, Receptor and Cholesterol.
His Cholesterol research incorporates elements of Genetics and Disease.
His Biochemistry research is multidisciplinary, incorporating perspectives in Alzheimer's disease and Cell biology.
His Apolipoprotein B research is multidisciplinary, incorporating elements of Membrane and Neurodegeneration.
His work in Endocrinology tackles topics such as Internal medicine which are related to areas like In vivo, In vitro, Chemical modification and Proteolysis.
His most cited work include:
- Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease (1165 citations)
- Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro (735 citations)
- Apolipoprotein E: Structure-Function Relationships (722 citations)
What are the main themes of his work throughout his whole career to date?
Karl H. Weisgraber mostly deals with Apolipoprotein E, Biochemistry, Apolipoprotein B, Lipoprotein and Internal medicine.
He studies Apolipoproteins E, a branch of Apolipoprotein E.
While the research belongs to areas of Biochemistry, he spends his time largely on the problem of Neurodegeneration, intersecting his research to questions surrounding Cell biology.
His Apolipoprotein B research incorporates themes from Genetics, Phospholipid and Lipoprotein lipase.
His Lipoprotein research includes themes of Lipid metabolism and Genetically modified mouse.
His research links Endocrinology with Internal medicine.
He most often published in these fields:
- Apolipoprotein E (72.86%)
- Biochemistry (41.43%)
- Apolipoprotein B (32.86%)
What were the highlights of his more recent work (between 2005-2019)?
- Apolipoprotein E (72.86%)
- Biochemistry (41.43%)
- Neurodegeneration (10.00%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Apolipoprotein E, Biochemistry, Neurodegeneration, Cell biology and Apolipoprotein B.
Apolipoprotein E is a subfield of Internal medicine that Karl H. Weisgraber explores.
In the field of Biochemistry, his study on Lipoprotein and Very low-density lipoprotein overlaps with subjects such as In situ.
His biological study spans a wide range of topics, including Molecular biology, Protein species, Alzheimer's disease, Protein structure and Mitochondrion.
Karl H. Weisgraber has researched Cell biology in several fields, including Trinucleotide repeat expansion, Neurite, Apolipoprotein e4, Astrocyte and Epitope.
His research integrates issues of Guanidine, Stereochemistry and Small molecule in his study of Apolipoprotein B.
Between 2005 and 2019, his most popular works were:
- Apolipoprotein E4: A Causative Factor and Therapeutic Target in Neuropathology, Including Alzheimer's Disease (709 citations)
- Apolipoprotein E structure: insights into function (396 citations)
- Apolipoprotein E: structure determines function, from atherosclerosis to Alzheimer's disease to AIDS. (317 citations)
In his most recent research, the most cited papers focused on:
Karl H. Weisgraber mainly investigates Neurodegeneration, Apolipoprotein E, Biochemistry, Apolipoprotein B and Apolipoproteins E.
His Neurodegeneration research incorporates elements of Mitochondrion, Function, Cell biology, Molecular biology and Alzheimer's disease.
As part of one scientific family, Karl H. Weisgraber deals mainly with the area of Apolipoprotein E, narrowing it down to issues related to the Cholesterol, and often Immunology.
His Biochemistry study frequently involves adjacent topics like Rational design.
His research investigates the connection with Apolipoproteins E and areas like Plasma protein binding which intersect with concerns in Genetics, Apolipophorin III, Receptor and Gene isoform.
His work on Very low-density lipoprotein as part of general Lipoprotein study is frequently linked to Phosphotungstic acid, Electron tomography and Negative stain, therefore connecting diverse disciplines of science.
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