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Biology and Biochemistry

D-Index
113
Citations
46347
World Ranking
857
National Ranking
535

Overview

Karl H. Weisgraber is affiliated with the University of California, San Francisco in the United States. Their research contributions focus primarily on the fields of biochemistry, genetics, and molecular biology.

The scholar's work includes an emphasis on molecular biology and genetics as subfields, reflecting an interest in fundamental biological processes at the molecular and genetic levels.

The main topics of Weisgraber's research cover prion diseases and protein misfolding, as well as animal genetics and reproduction. These topics indicate a focus on both disease mechanisms related to protein structure and broader genetic influences on animal reproduction.

One paper has been documented from the year 2020:

  • Genes contributing to prion pathogenesis, 2020, UNC Libraries

Frequent co-authors involved in this line of research include:

  • Gültekin Tamgüney
  • Kurt Giles
  • David V. Glidden
  • Pierre Lessard
  • Holger Wille

Publications have been featured in venues such as:

  • UNC Libraries

Best Publications

  • Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

    Warren J. Strittmatter;Karl H. Weisgraber;David Y. Huang;Li Ming Dong

  • Plasma lipoproteins: apolipoprotein structure and function.

    R W Mahley;T L Innerarity;S C Rall;K H Weisgraber

  • Apolipoprotein E4: A Causative Factor and Therapeutic Target in Neuropathology, Including Alzheimer's Disease

    Robert W. Mahley;Karl H. Weisgraber;Yadong Huang

  • Apolipoprotein E: Structure-Function Relationships

    Karl H. Weisgraber

  • Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain.

    R E Pitas;J K Boyles;S H Lee;D Hui

  • Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro

    B. P. Nathan;S. Bellosta;D. A. Sanan;K. H. Weisgraber

  • Human apolipoprotein E. The complete amino acid sequence.

    S C Rall;K H Weisgraber;R W Mahley

  • Human E apoprotein heterogeneity. Cysteine-arginine interchanges in the amino acid sequence of the apo-E isoforms.

    K H Weisgraber;S C Rall;R W Mahley

  • Three-dimensional structure of the LDL receptor-binding domain of human apolipoprotein E.

    Charles Wilson;Mark R. Wardell;Karl H. Weisgraber;Robert W. Mahley

  • Abnormal lipoprotein receptor-binding activity of the human E apoprotein due to cysteine-arginine interchange at a single site.

    K H Weisgraber;T L Innerarity;R W Mahley

  • A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve.

    J K Boyles;C D Zoellner;L J Anderson;L M Kosik

  • Role of lysine residues of plasma lipoproteins in high affinity binding to cell surface receptors on human fibroblasts.

    K H Weisgraber;T L Innerarity;R W Mahley

  • Apolipoprotein E structure: insights into function

    Danny M. Hatters;Clare A. Peters-Libeu;Karl H. Weisgraber

  • Familial defective apolipoprotein B-100: low density lipoproteins with abnormal receptor binding

    Thomas L. Innerarity;Karl H. Weisgraber;Kay S. Arnold;Robert W. Mahley

  • Opposing effects of apolipoproteins E and C on lipoprotein binding to low density lipoprotein receptor-related protein

    Robert C. Kowal;Joachim Herz;Karl H. Weisgraber;Robert W. Mahley

  • Familial defective apolipoprotein B-100: a mutation of apolipoprotein B that causes hypercholesterolemia.

    Thomas L. Innerarity;Robert W. Mahley;Karl H. Weisgraber;Thomas P. Bersot

  • Apolipoprotein E: structure determines function, from atherosclerosis to Alzheimer's disease to AIDS.

    Robert W. Mahley;Karl H. Weisgraber;Yadong Huang

  • Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease

    Warren J. Strittmatter;Ann M. Saunders;Michel Goedert;Karl H. Weisgraber

  • Hypothesis: Microtubule Instability and Paired Helical Filament Formation in the Alzheimer Disease Brain Are Related to Apolipoprotein E Genotype

    Warren J. Strittmatter;Karl H. Weisgraber;Michel Goedert;Ann M. Saunders

  • Proposed nomenclature of apoE isoproteins, apoE genotypes, and phenotypes.

    Vassilis I. Zannis;Jan L. Breslow;Gerd Utermann;Robert W. Mahley

Frequent Co-Authors

Robert W. Mahley
Robert W. Mahley University of California, San Francisco
Thomas L. Innerarity
Thomas L. Innerarity University of California, San Francisco
Yadong Huang
Yadong Huang Gladstone Institutes
Michael C. Phillips
Michael C. Phillips University of Pennsylvania
Warren J. Strittmatter
Warren J. Strittmatter Duke University
Sissel Lund-Katz
Sissel Lund-Katz University of Pennsylvania
Ann M. Saunders
Ann M. Saunders Durham University
Allen D. Roses
Allen D. Roses Duke University
Robert E. Pitas
Robert E. Pitas University of California, San Francisco
Sergio Fazio
Sergio Fazio Oregon Health & Science University

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