D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 55 Citations 14,747 70 World Ranking 10304 National Ranking 4509

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Biochemistry
  • Internal medicine

Robert E. Pitas mainly focuses on Apolipoprotein E, Internal medicine, Endocrinology, Receptor and Apolipoprotein B. His work on Apolipoproteins E as part of general Apolipoprotein E research is frequently linked to Membrane biogenesis, bridging the gap between disciplines. His work on Lipid metabolism, Insulin resistance and Insulin as part of general Internal medicine research is frequently linked to Enolase and Acyl-CoA, thereby connecting diverse disciplines of science.

Robert E. Pitas has included themes like Genetically modified mouse and Downregulation and upregulation in his Endocrinology study. His Receptor study combines topics from a wide range of disciplines, such as Very low-density lipoprotein and Central nervous system. His studies deal with areas such as Cell and Internalization as well as Very low-density lipoprotein.

His most cited work include:

  • Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro (735 citations)
  • Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system. (675 citations)
  • Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain. (596 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Biochemistry, Apolipoprotein E, Molecular biology, Receptor and Internal medicine. His study in Apolipoprotein E is interdisciplinary in nature, drawing from both Neurite, Cell biology, Gene isoform and Apolipoprotein B. His research in Molecular biology intersects with topics in Genetically modified mouse, Kidney and Scavenger receptor.

His Receptor research is multidisciplinary, relying on both LDL receptor and Low-density lipoprotein. Robert E. Pitas works mostly in the field of Internal medicine, limiting it down to topics relating to Endocrinology and, in certain cases, Fatty liver, as a part of the same area of interest. Robert E. Pitas has researched Very low-density lipoprotein in several fields, including In vitro and Lipid droplet.

He most often published in these fields:

  • Biochemistry (46.67%)
  • Apolipoprotein E (41.33%)
  • Molecular biology (42.67%)

What were the highlights of his more recent work (between 2000-2014)?

  • Biochemistry (46.67%)
  • Internal medicine (32.00%)
  • Endocrinology (32.00%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Biochemistry, Internal medicine, Endocrinology, Scavenger receptor and Molecular biology. As part of the same scientific family, Robert E. Pitas usually focuses on Internal medicine, concentrating on Methionine and intersecting with Beta oxidation, Lipogenesis, Hypermetabolism and Steatosis. Robert E. Pitas integrates Endocrinology with Leptin receptor in his study.

His Scavenger receptor research is multidisciplinary, incorporating elements of Biglycan, Decorin, Cell adhesion, Cell adhesion molecule and Extracellular matrix. The various areas that Robert E. Pitas examines in his Molecular biology study include Proteoglycan, Receptor and Mutant. His biological study spans a wide range of topics, including Apolipoprotein E, In vitro, Allele and Metabolism.

Between 2000 and 2014, his most popular works were:

  • Increased insulin and leptin sensitivity in mice lacking acyl CoA:diacylglycerol acyltransferase 1 (301 citations)
  • Mice fed a lipogenic methionine-choline-deficient diet develop hypermetabolism coincident with hepatic suppression of SCD-1. (180 citations)
  • Antisense Oligonucleotide Directed to Human Apolipoprotein B-100 Reduces Lipoprotein(a) Levels and Oxidized Phospholipids on Human Apolipoprotein B-100 Particles in Lipoprotein(a) Transgenic Mice (130 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Biochemistry
  • Internal medicine

Robert E. Pitas spends much of his time researching Apolipoprotein B, Biochemistry, Lipoprotein, Internal medicine and Endocrinology. His work carried out in the field of Apolipoprotein B brings together such families of science as Proteoglycan, Proteoglycan binding, Low-density lipoprotein, LDL receptor and Conformational change. His Biochemistry study often links to related topics such as Molecular biology.

His studies in Lipoprotein integrate themes in fields like Intraperitoneal injection and Transgene. His study in the fields of Lipid metabolism, Insulin resistance and Insulin under the domain of Internal medicine overlaps with other disciplines such as Acyl-CoA and Leptin receptor. His Endocrinology research integrates issues from Fatty liver, Downregulation and upregulation, Fatty acid and Methionine.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro

B. P. Nathan;S. Bellosta;D. A. Sanan;K. H. Weisgraber.
Science (1994)

987 Citations

Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain.

R E Pitas;J K Boyles;S H Lee;D Hui.
Journal of Biological Chemistry (1987)

965 Citations

Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system.

J K Boyles;R E Pitas;E Wilson;R W Mahley.
Journal of Clinical Investigation (1985)

933 Citations

Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins.

Robert E. Pitas;Janet K. Boyles;Susan H. Lee;Donna Foss.
Biochimica et Biophysica Acta (1987)

831 Citations

A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve.

J K Boyles;C D Zoellner;L J Anderson;L M Kosik.
Journal of Clinical Investigation (1989)

757 Citations

Acetoacetylated lipoproteins used to distinguish fibroblasts from macrophages in vitro by fluorescence microscopy

R E Pitas;T L Innerarity;J N Weinstein;R W Mahley.
Arteriosclerosis, Thrombosis, and Vascular Biology (1981)

532 Citations

Inhibition of lipoprotein binding to cell surface receptors of fibroblasts following selective modification of arginyl residues in arginine-rich and B apoproteins.

R W Mahley;T L Innerarity;R E Pitas;K H Weisgraber.
Journal of Biological Chemistry (1977)

513 Citations

Increased insulin and leptin sensitivity in mice lacking acyl CoA:diacylglycerol acyltransferase 1

Hubert C. Chen;Steven J. Smith;Zuleika Ladha;Dalan R. Jensen.
Journal of Clinical Investigation (2002)

459 Citations

Binding of arginine-rich (E) apoprotein after recombination with phospholipid vesicles to the low density lipoprotein receptors of fibroblasts.

T L Innerarity;R E Pitas;R W Mahley.
Journal of Biological Chemistry (1979)

431 Citations

Expression of human apolipoprotein E3 or E4 in the brains of Apoe-/- mice: isoform-specific effects on neurodegeneration.

Manuel Buttini;Matthias Orth;Stefano Bellosta;Hassibullah Akeefe.
The Journal of Neuroscience (1999)

422 Citations

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