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D-Index & Metrics

Biology and Biochemistry

D-Index
75
Citations
17990
World Ranking
5382
National Ranking
2551

Overview

David Y. Hui is affiliated with the University of Cincinnati Medical Center in the United States. Their research spans several interconnected scientific disciplines with a focus on medicine, biochemistry, genetics, and molecular biology.

The main fields of study covered in their work include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

In terms of subfields, their research interests extend to:

  • Immunology
  • Molecular Biology
  • Epidemiology
  • Endocrinology, Diabetes and Metabolism
  • Surgery

Their primary topics of investigation include:

  • Atherosclerosis and Cardiovascular Diseases
  • Adipokines, Inflammation, and Metabolic Diseases
  • Lipoproteins and Cardiovascular Health
  • Diet and metabolism studies
  • Immune cells in cancer
  • Liver Disease Diagnosis and Treatment
  • Diet, Metabolism, and Disease

David Y. Hui has published extensively in various scientific journals, with frequent contributions to:

  • Journal of Biological Chemistry
  • International Journal of Molecular Sciences
  • Frontiers in Immunology
  • Arteriosclerosis Thrombosis and Vascular Biology
  • Science Translational Medicine

Notable recent papers authored by David Y. Hui include:

  • Apolipoprotein E in Cardiometabolic and Neurological Health and Diseases (2022) in International Journal of Molecular Sciences
  • Receptor-independent fluid-phase macropinocytosis promotes arterial foam cell formation and atherosclerosis (2022) in Science Translational Medicine
  • Sexual Dimorphism in Lipid Metabolism and Gut Microbiota in Mice Fed a High-Fat Diet (2023) in Nutrients
  • Protein Phosphatase 2A Activation Via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome (2021) in Circulation Research
  • Apolipoprotein E receptor 2 deficiency decreases endothelial adhesion of monocytes and protects against autoimmune encephalomyelitis (2021) in Science Immunology

The scientist collaborates frequently with several co-authors, including:

  • Anja Jaeschke
  • April Haller
  • Patrick R. Wolfkiel
  • Vanessa M Turkson
  • Anastasia Sacharidou

Best Publications

  • Obesity-associated improvements in metabolic profile through expansion of adipose tissue

    Ja Young Kim;Esther Van De Wall;Mathieu Laplante;Anthony Azzara

  • Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain.

    R E Pitas;J K Boyles;S H Lee;D Hui

  • A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve.

    J K Boyles;C D Zoellner;L J Anderson;L M Kosik

  • The central melanocortin system directly controls peripheral lipid metabolism

    Ruben Nogueiras;Petra Wiedmer;Diego Perez-Tilve;Christelle Veyrat-Durebex

  • Two independent lipoprotein receptors on hepatic membranes of dog, swine, and man. Apo-B,E and apo-E receptors.

    Robert W. Mahley;David Y. Hui;Thomas L. Innerarity;Karl H. Weisgraber

  • Lipoprotein binding to canine hepatic membranes. Metabolically distinct apo-E and apo-B,E receptors.

    D.Y. Hui;T.L. Innerarity;R.W. Mahley

  • Carboxyl ester lipase: structure-function relationship and physiological role in lipoprotein metabolism and atherosclerosis.

    David Y. Hui;Philip N. Howles

  • HIV protease inhibitor induces fatty acid and sterol biosynthesis in liver and adipose tissues due to the accumulation of activated sterol regulatory element-binding proteins in the nucleus.

    Tara M. Riddle;David G. Kuhel;Laura A. Woollett;Carl J. Fichtenbaum

  • Non-nuclear estrogen receptor α signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice

    Ken L. Chambliss;Qian Wu;Sarah Oltmann;Eddy S. Konaniah

  • Accumulation of apolipoprotein E-rich high density lipoproteins in hyperalphalipoproteinemic human subjects with plasma cholesteryl ester transfer protein deficiency.

    S Yamashita;D L Sprecher;N Sakai;Y Matsuzawa

  • Apolipoprotein E Inhibits Platelet-derived Growth Factor-induced Vascular Smooth Muscle Cell Migration and Proliferation by Suppressing Signal Transduction and Preventing Cell Entry to G1 Phase

    Masato Ishigami;Debi K. Swertfeger;Norman A. Granholm;David Y. Hui

  • Dietary Free and Esterified Cholesterol Absorption in Cholesterol Esterase (Bile Salt-stimulated Lipase) Gene-targeted Mice

    Philip N. Howles;Christopher P. Carter;David Y. Hui

  • Adipocyte LDL receptor–related protein–1 expression modulates postprandial lipid transport and glucose homeostasis in mice

    Susanna M. Hofmann;Li Zhou;Diego Perez-Tilve;Todd Greer

  • Lysosomal acid lipase-deficient mice: depletion of white and brown fat, severe hepatosplenomegaly, and shortened life span

    Hong Du;Martin Heur;Ming Duanmu;Gregory A. Grabowski

  • The Role of Apolipoprotein A-I Helix 10 in Apolipoprotein-mediated Cholesterol Efflux via the ATP-binding Cassette Transporter ABCA1*

    Stacey E. Panagotopulos;Scott R. Witting;Erica M. Horace;David Y. Hui

  • Pulmonary Surfactant Proteins A and D Are Potent Endogenous Inhibitors of Lipid Peroxidation and Oxidative Cellular Injury

    James P. Bridges;Harold W. Davis;Mamatha Damodarasamy;Yoshio Kuroki

  • Engineering a lysosomal enzyme with a derivative of receptor-binding domain of apoE enables delivery across the blood–brain barrier

    Daren Wang;Salim S. El-Amouri;Mei Dai;Chia-Yi Kuan

  • Binding of chylomicron remnants and beta-very low density lipoproteins to hepatic and extrahepatic lipoprotein receptors. A process independent of apolipoprotein B48.

    D Y Hui;T L Innerarity;R W Milne;Y L Marcel

  • Apolipoprotein AIV: a potent endogenous inhibitor of lipid oxidation

    Xiaofa Qin;Debi K. Swertfeger;Shuqin Zheng;David Y. Hui

  • Effects of HIV protease inhibitor therapy on lipid metabolism.

    David Y. Hui

Frequent Co-Authors

Robert W. Mahley
Robert W. Mahley University of California, San Francisco
Thomas L. Innerarity
Thomas L. Innerarity University of California, San Francisco
Patrick Tso
Patrick Tso University of Cincinnati
Joachim Herz
Joachim Herz The University of Texas Southwestern Medical Center
W. Sean Davidson
W. Sean Davidson University of Cincinnati
Philip W. Shaul
Philip W. Shaul The University of Texas Southwestern Medical Center
Matthias H. Tschöp
Matthias H. Tschöp Technical University of Munich
David P. Witte
David P. Witte Cincinnati Children's Hospital Medical Center
Paul T. Pfluger
Paul T. Pfluger Helmholtz Zentrum München
Bruce J. Aronow
Bruce J. Aronow Cincinnati Children's Hospital Medical Center

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