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Neuroscience

D-Index
66
Citations
17516
World Ranking
2988
National Ranking
258

Overview

Paul T. Pfluger is affiliated with Helmholtz Zentrum München in Germany. Their research primarily focuses on medicine and the intersections of biochemistry, genetics, and molecular biology.

Their work covers a range of subfields including molecular biology, physiology, endocrine and autonomic systems, epidemiology, and cancer research. This diverse expertise is reflected in numerous publications across prominent research venues.

Frequent publication venues include:

  • Molecular Metabolism
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Metabolism
  • Nature Communications
  • eLife

Pfluger has contributed extensively to various topics in metabolic and neuroendocrine research. Main areas of study include:

  • Regulation of Appetite and Obesity
  • Adipokines, Inflammation, and Metabolic Diseases
  • Adipose Tissue and Metabolism
  • Dietary Effects on Health
  • Neuroendocrine regulation and behavior
  • Diet and metabolism studies
  • Thyroid Disorders and Treatments

Their research involves significant collaboration with other scientists, with frequent co-authors including Sonja C. Schriever, Timo D. Müller, Matthias H. Tschöp, Miriam Bernecker, and Anna Molenaar.

Selected recent publications illustrate their research scope and focus:

  • Obesity-associated hyperleptinemia alters the gliovascular interface of the hypothalamus to promote hypertension, 2021, Cell Metabolism
  • Adipocyte-derived extracellular vesicles increase insulin secretion through transport of insulinotropic protein cargo, 2023, Nature Communications
  • Estradiol regulates leptin sensitivity to control feeding via hypothalamic Cited1, 2023, Cell Metabolism
  • Food-seeking behavior is triggered by skin ultraviolet exposure in males, 2022, Nature Metabolism
  • Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity, 2020, Journal of Clinical Investigation

The scope of their publications highlights research into the molecular mechanisms underlying metabolic diseases, hormonal regulation of appetite, and the neuroendocrine factors influencing behavior and insulin sensitivity. Their work contributes to better understanding of metabolic disorders such as obesity, diabetes, and hypertension.

Best Publications

  • Sirt1 protects against high-fat diet-induced metabolic damage

    Paul T. Pfluger;Daniel Herranz;Susana Velasco-Miguel;Manuel Serrano

  • A guide to analysis of mouse energy metabolism

    Matthias H Tschöp;John R Speakman;John R Speakman;Jonathan R S Arch;Johan Auwerx

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  • Sirtuin 1 and Sirtuin 3: Physiological Modulators of Metabolism

    Ruben Nogueiras;Kirk M. Habegger;Nilika Chaudhary;Brian Finan

  • A new glucagon and GLP-1 co-agonist eliminates obesity in rodents

    Jonathan Day;Nickki Ottaway;James Patterson;Vasily Gelfanov

  • A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents

    Brian Finan;Bin Yang;Nickki Ottaway;David L Smiley

  • Unimolecular Dual Incretins Maximize Metabolic Benefits in Rodents, Monkeys, and Humans

    Brian Finan;Brian Finan;Tao Ma;Nickki Ottaway;Timo D. Müller

  • Ghrelin action in the brain controls adipocyte metabolism

    Claudia Theander-Carrillo;Petra Wiedmer;Philippe Cettour-Rose;Ruben Nogueiras

  • Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability

    Cristina García-Cáceres;Carmelo Quarta;Luis Varela;Yuanqing Gao

  • The central melanocortin system directly controls peripheral lipid metabolism

    Ruben Nogueiras;Petra Wiedmer;Diego Perez-Tilve;Christelle Veyrat-Durebex

  • GOAT links dietary lipids with the endocrine control of energy balance

    Henriette Kirchner;Jesus A. Gutierrez;Patricia J. Solenberg;Paul T. Pfluger

  • Synaptic input organization of the melanocortin system predicts diet-induced hypothalamic reactive gliosis and obesity

    Tamas L. Horvath;Beatrix Sarman;Cristina García-Cáceres;Pablo J. Enriori

  • Effects of obestatin on energy balance and growth hormone secretion in rodents.

    Rubén Nogueiras;Paul Pfluger;Sulay Tovar;Myrtha Arnold

  • Targeted estrogen delivery reverses the metabolic syndrome

    Brian Finan;Bin Yang;Nickki Ottaway;Kerstin Stemmer

  • Glucose and Weight Control in Mice with a Designed Ghrelin O-Acyltransferase Inhibitor

    Brad P. Barnett;Yousang Hwang;Martin S. Taylor;Henriette Kirchner

  • Vitamin E activates gene expression via the pregnane X receptor.

    Nico Landes;Paul Pfluger;Dirk Kluth;Marc Birringer

  • Fibroblast Growth Factor 21 Mediates Specific Glucagon Actions

    Kirk M. Habegger;Kerstin Stemmer;Christine Cheng;Timo D. Müller

  • Effect of human body weight changes on circulating levels of peptide YY and peptide YY3-36.

    P T Pfluger;Juliane Kampe;Juliane Kampe;T R Castaneda;T Vahl

  • Direct Control of Peripheral Lipid Deposition by CNS GLP-1 Receptor Signaling Is Mediated by the Sympathetic Nervous System and Blunted in Diet-Induced Obesity

    Ruben Nogueiras;Diego Pérez-Tilve;Christelle Veyrat-Durebex;Donald A. Morgan

  • Simultaneous deletion of ghrelin and its receptor increases motor activity and energy expenditure

    Paul Thomas Pfluger;Henriette Kirchner;Susanne Gunnel;Brigitte Schrott

  • Adipocyte LDL receptor–related protein–1 expression modulates postprandial lipid transport and glucose homeostasis in mice

    Susanna M. Hofmann;Li Zhou;Diego Perez-Tilve;Todd Greer

  • Ghrelin enhances olfactory sensitivity and exploratory sniffing in rodents and humans.

    Jenny Tong;Erica Mannea;Pascaline Aimé;Paul T Pfluger

Frequent Co-Authors

Stephen C. Benoit
Stephen C. Benoit University of Cincinnati
Martin Hrabé de Angelis
Martin Hrabé de Angelis Technical University of Munich

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