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Biology and Biochemistry

D-Index
68
Citations
13672
World Ranking
7940
National Ranking
3598

Overview

Rick G. Schnellmann is affiliated with the Medical University of South Carolina in the United States. Their research contributions span multiple fields including Medicine, Biochemistry, Genetics and Molecular Biology, and Neuroscience, with publication counts of 39, 29, and 21 respectively. Their work involves several subfields such as Molecular Biology, Neurology, Pathology and Forensic Medicine, Epidemiology, and Clinical Biochemistry.

The main topics explored in their research encompass mitochondrial function and pathology, neuroinflammation and neurodegeneration mechanisms, peroxisome proliferator-activated receptors, spinal cord injury research, neurological disease mechanisms and treatments, metabolism and genetic disorders, as well as neurogenesis and neuroplasticity mechanisms.

Frequent co-authors collaborating with Schnellmann include:

  • Natalie E. Scholpa
  • Kristian P. Doyle
  • Danielle A. Becktel
  • Epiphani C. Simmons
  • Marco A. Tavera-Garcia

Schnellmann's publications are often featured in specific scientific journals with several appearances in the Journal of the American Society of Nephrology, bioRxiv (Cold Spring Harbor Laboratory), The FASEB Journal, Experimental Neurology, and the Journal of Pharmacology and Experimental Therapeutics.

Notable recent papers include:

  • "Mitochondrial biogenesis as a therapeutic target for traumatic and neurodegenerative CNS diseases", 2020, Experimental Neurology
  • "Pharmacological Targeting of Mitochondria in Diabetic Kidney Disease", 2022, Pharmacological Reviews
  • "Metformin: Experimental and Clinical Evidence for a Potential Role in Emphysema Treatment", 2021, American Journal of Respiratory and Critical Care Medicine
  • "Increased fatty acid metabolism and decreased glycolysis are hallmarks of metabolic reprogramming within microglia in degenerating white matter during recovery from experimental stroke", 2023, Journal of Cerebral Blood Flow & Metabolism
  • "Measurement of Cell Death in Mammalian Cells", 2021, Current Protocols

Best Publications

  • A Death-Promoting Role for Extracellular Signal-Regulated Kinase

    Shougang Zhuang;Rick G. Schnellmann

  • The role of calpain in oncotic cell death.

    Xiuli Liu;Terry Van Vleet;Rick G Schnellmann

  • Calpains, mitochondria, and apoptosis

    Matthew A. Smith;Rick G. Schnellmann;Rick G. Schnellmann

  • Persistent disruption of mitochondrial homeostasis after acute kidney injury.

    Jason A. Funk;Rick G. Schnellmann;Rick G. Schnellmann

  • Measurement of Cell Death in Mammalian Cells

    Brian S. Cummings;Lauren P. Wills;Rick G. Schnellmann

  • Calpain 10: a mitochondrial calpain and its role in calcium-induced mitochondrial dysfunction.

    David D. Arrington;Terry R. Van Vleet;Rick G. Schnellmann

  • Signaling of mitochondrial biogenesis following oxidant injury.

    Kyle A. Rasbach;Rick G. Schnellmann

  • Mitochondrial Biogenesis as a Pharmacological Target: A New Approach to Acute and Chronic Diseases

    Ryan M. Whitaker;Daniel Corum;Craig C. Beeson;Rick G. Schnellmann

  • ERK promotes hydrogen peroxide-induced apoptosis through caspase-3 activation and inhibition of Akt in renal epithelial cells

    Shougang Zhuang;Yan Yan;Rebecca A. Daubert;Jiahuai Han

  • Toxic nephropathy: environmental chemicals.

    Terry R Van Vleet;Rick G Schnellmann

  • A high throughput respirometric assay for mitochondrial biogenesis and toxicity

    Craig C. Beeson;Gyda C. Beeson;Rick G. Schnellmann

  • Accelerated recovery of renal mitochondrial and tubule homeostasis with SIRT1/PGC-1α activation following ischemia-reperfusion injury.

    Jason A. Funk;Rick G. Schnellmann;Rick G. Schnellmann

  • PGC-1alpha over-expression promotes recovery from mitochondrial dysfunction and cell injury.

    Kyle A. Rasbach;Rick G. Schnellmann

  • Quantitative analysis of mitochondrial morphology and membrane potential in living cells using high-content imaging, machine learning, and morphological binning.

    Anthony P. Leonard;Robert B. Cameron;Jaime L. Speiser;Bethany J. Wolf

  • Nationwide and Long-Term Survey of Primary Glomerulonephritis in Japan as Observed in 1,850 Biopsied Cases

    M. Brack;C. Schroeder;M. Fooke;W. Schlumberger

  • Suppressed mitochondrial biogenesis in folic acid-induced acute kidney injury and early fibrosis.

    L. Jay Stallons;Ryan M. Whitaker;Rick G. Schnellmann;Rick G. Schnellmann

  • H2O2-induced transactivation of EGF receptor requires Src and mediates ERK1/2, but not Akt, activation in renal cells.

    Shougang Zhougang;Rick G. Schnellmann

  • L-ascorbic acid regulates growth and metabolism of renal cells: improvements in cell culture

    G. Nowak;R. G. Schnellmann

  • Improved culture conditions stimulate gluconeogenesis in primary cultures of renal proximal tubule cells

    G. Nowak;R. G. Schnellmann

  • Calpain mediates progressive plasma membrane permeability and proteolysis of cytoskeleton-associated paxillin, talin, and vinculin during renal cell death.

    Xiuli Liu;Rick G. Schnellmann

Frequent Co-Authors

Craig C. Beeson
Craig C. Beeson Medical University of South Carolina
John J. Lemasters
John J. Lemasters Medical University of South Carolina
Gary W. Miller
Gary W. Miller Columbia University
Lazaro J. Mandel
Lazaro J. Mandel Duke University
Michael P. Murphy
Michael P. Murphy University of Cambridge
Darryl C. Zeldin
Darryl C. Zeldin National Institutes of Health
Jay A. Gingrich
Jay A. Gingrich Columbia University
James A. Shayman
James A. Shayman University of Michigan–Ann Arbor
Steven R. Gullans
Steven R. Gullans Brigham and Women's Hospital
Edward Balish
Edward Balish University of Wisconsin–Madison

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