World's Best Scientists 2026 revealed!
Stefano Mangani

Stefano Mangani

D-Index & Metrics

Chemistry

D-Index
50
Citations
9104
World Ranking
14369
National Ranking
492

Overview

Stefano Mangani is affiliated with the University of Siena in Italy and has contributed to the fields of Biochemistry, Genetics and Molecular Biology as well as Medicine. Their research encompasses several subfields, including Molecular Biology, Epidemiology, Infectious Diseases, Materials Chemistry, and Molecular Medicine.

The main topics of Stefano Mangani's research work cover a range of biochemical and medical concerns: biochemical and molecular research, Pneumocystis jirovecii pneumonia detection and treatment, Trypanosoma species research and implications, antibiotic resistance in bacteria, tuberculosis research and epidemiology, iron metabolism and disorders, and the role of trace elements in health.

Stefano Mangani's publication record includes work in a number of scientific journals, with frequent publications in the following venues:

  • European Journal of Medicinal Chemistry
  • Journal of Medicinal Chemistry
  • Chemistry - A European Journal
  • ACS Infectious Diseases
  • Pharmaceuticals

Some recent papers authored or co-authored by Stefano Mangani include:

  • ANT2681: SAR Studies Leading to the Identification of a Metallo-β-lactamase Inhibitor with Potential for Clinical Use in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing Enterobacteriaceae (2020), published in ACS Infectious Diseases
  • 4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-β-lactamase inhibitors (2020), published in European Journal of Medicinal Chemistry
  • Discovery of ANT3310, a Novel Broad-Spectrum Serine β-Lactamase Inhibitor of the Diazabicyclooctane Class, Which Strongly Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacterales and Acinetobacter baumannii (2020), published in Journal of Medicinal Chemistry
  • Iron Biomineral Growth from the Initial Nucleation Seed in L-Ferritin (2020), published in Chemistry - A European Journal
  • 1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity (2021), published in European Journal of Medicinal Chemistry

Frequent collaborators in Stefano Mangani's research include:

  • Cecilia Pozzi
  • Giusy Tassone
  • Maria Paola Costi
  • Lorenzo Tagliazucchi
  • Giacomo Landi

Best Publications

  • A new proposal for urease mechanism based on the crystal structures of the native and inhibited enzyme from Bacillus pasteurii: why urea hydrolysis costs two nickels.

    Stefano Benini;Wojciech R Rypniewski;Keith S Wilson;Silvia Miletti

  • Carbonic anhydrase activators: X-ray crystallographic and spectroscopic investigations for the interaction of isozymes I and II with histamine.

    Fabrizio Briganti;Stefano Mangani;Pierluigi Orioli;Andrea Scozzafava

  • Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- And Metallo-β-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections

    B. Liu;R. E. L. Trout;G.-H. Chu;D. Mcgarry

  • Structural Insight into Potent Broad-Spectrum Inhibition with Reversible Recyclization Mechanism: Avibactam in Complex with CTX-M-15 and Pseudomonas aeruginosa AmpC β-Lactamases

    Sushmita D. Lahiri;Stefano Mangani;Thomas Durand-Reville;Manuela Benvenuti

  • Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-6.

    Arduino A. Mangoni;Catherine Guillou;Jean Jacques Vanden Eynde;Christopher Hulme

  • The complex of Bacillus pasteurii urease with acetohydroxamate anion from X-ray data at 1.55 A resolution.

    S. Benini;W. R. Rypniewski;K. S. Wilson;S. Miletti

  • Crystallization of soluble proteins in vapor diffusion for x-ray crystallography

    Manuela Benvenuti;Stefano Mangani;Stefano Mangani

  • A redox switch in CopC: an intriguing copper trafficking protein that binds copper(I) and copper(II) at different sites.

    Fabio Arnesano;Lucia Banci;Ivano Bertini;Stefano Mangani

  • Structural properties of the nickel ions in urease: novel insights into the catalytic and inhibition mechanisms

    Stefano Ciurli;Stefano Benini;Wojciech R. Rypniewski;Keith S. Wilson

  • VNRX-5133 (Taniborbactam), a broad-spectrum inhibitor of serine- And metallo-β-lactamases, restores activity of cefepime in enterobacterales and Pseudomonas aeruginosa

    Jodie C. Hamrick;Jean-Denis Docquier;Tsuyoshi Uehara;Cullen L. Myers

  • Crystal Structure of the OXA-48 β-Lactamase Reveals Mechanistic Diversity among Class D Carbapenemases

    Jean Denis Docquier;Vito Calderone;Vito Calderone;Filomena De Luca;Manuela Benvenuti

  • Molecular Details of Urease Inhibition by Boric Acid: Insights into the Catalytic Mechanism

    Stefano Benini;Wojciech R. Rypniewski;Keith S. Wilson;T. Stefano Mangani

  • Conformational variability of matrix metalloproteinases: beyond a single 3D structure.

    Ivano Bertini;Vito Calderone;Marta Cosenza;Marco Fragai

  • Structure-based rationalization of urease inhibition by phosphate: novel insights into the enzyme mechanism

    Benini S;Rypniewski Wr;Wilson Ks;Ciurli S

  • The complex of Bacillus pasteurii urease with beta-mercaptoethanol from X-ray data at 1.65-A resolution

    S. Benini;W. R. Rypniewski;K. S. Wilson;S. Ciurli

  • The Crystal Structure of Yeast Copper Thionein: the solution of a long lasting Enigma.

    Vito Calderone;Benedikt Dolderer;Hans-Juergen Hartmann;Hartmut Echner

  • Structural investigation of cisplatin-protein interactions: selective platination of His19 in a cuprozinc superoxide dismutase.

    Vito Calderone;Angela Casini;Stefano Mangani;Luigi Messori

  • Solution Structure of Cox11, a Novel Type of β-Immunoglobulin-like Fold Involved in CuB Site Formation of Cytochrome c Oxidase

    Lucia Banci;Ivano Bertini;Francesca Cantini;Simone Ciofi-Baffoni

  • A hint for the function of human Sco1 from different structures.

    Lucia Banci;Ivano Bertini;Vito Calderone;Simone Ciofi-Baffoni

  • Molecular basis of selective inhibition and slow reversibility of avibactam against class D carbapenemases: A structure-guided study of OXA-24 and OXA-48

    Sushmita D. Lahiri;Stefano Mangani;Haris Jahić;Manuela Benvenuti

  • Crystal structure of reduced bovine erythrocyte superoxide dismutase at 1.9 A resolution.

    Wojciech R. Rypniewski;Stefano Mangani;Bruno Bruni;Pier Luigi Orioli

Frequent Co-Authors

Ivano Bertini
Ivano Bertini University of Florence
Lucia Banci
Lucia Banci University of Florence
Rebecca C. Wade
Rebecca C. Wade Heidelberg Institute for Theoretical Studies
Andrea Scozzafava
Andrea Scozzafava University of Florence
Paola Turano
Paola Turano University of Florence
Keith S. Wilson
Keith S. Wilson University of York
Gian Maria Rossolini
Gian Maria Rossolini University of Florence
Antonio Bianchi
Antonio Bianchi University of Florence
Piero Paoletti
Piero Paoletti University of Florence
Claudio Luchinat
Claudio Luchinat University of Florence

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Chemistry in the USA opens doors to diverse career options beyond traditional research and laboratory roles. Many students explore related fields that combine chemistry knowledge with practical skills to enhance their career prospects.

For example, earning a paralegal degree can be a strategic move for those interested in legal aspects of chemical patents or regulatory compliance. Understanding paralegal salary trends can help gauge the financial benefits of this path.

Pharmaceutical sales representatives play a critical role in connecting chemical innovations with healthcare providers. Learning about pharmaceutical sales salary provides valuable insight into the earning potential while considering this dynamic career.

Alternatively, students may pursue advanced schooling to become a pharmacist, a profession requiring extensive education but offering rewarding opportunities in healthcare. Discovering how much schooling to be a pharmacist helps set realistic expectations.

For those drawn to forensic science, becoming a medical examiner assistant is a meaningful option. Knowing how to become a medical examiner assistant, along with job outlook and necessary education, supports informed career planning in this specialized area.

Best Scientists Citing Stefano Mangani

Trending Scientists

Recently Published Articles