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Shannon K. McDonnell

Shannon K. McDonnell

D-Index & Metrics

Medicine

D-Index
77
Citations
27837
World Ranking
18292
National Ranking
9126

Overview

Shannon K. McDonnell is affiliated with the Mayo Clinic in the United States and has a research focus primarily in medicine with notable contributions in biochemistry, genetics, and molecular biology. Their work intersects multiple subfields including genetics, pulmonary and respiratory medicine, molecular biology, cancer research, and nephrology.

The main topics of their research encompass prostate cancer treatment and research, genetic associations and epidemiology, prostate cancer diagnosis and treatment, liver disease diagnosis and treatment, kidney stones and urolithiasis treatments, genetic and kidney cyst diseases, alongside cancer-related molecular mechanisms research.

McDonnell's recent publications include the following papers:

  • Rare Germline Variants in ATM Predispose to Prostate Cancer: A PRACTICAL Consortium Study (2021), published in European Urology Oncology
  • Two-stage Study of Familial Prostate Cancer by Whole-exome Sequencing and Custom Capture Identifies 10 Novel Genes Associated with the Risk of Prostate Cancer (2020), published in European Urology
  • A Genetic Risk Score to Personalize Prostate Cancer Screening, Applied to Population Data (2020), published in Cancer Epidemiology Biomarkers & Prevention
  • Polygenic risk for prostate cancer: Decreasing relative risk with age but little impact on absolute risk (2022), published in The American Journal of Human Genetics
  • Admix-kit: an integrated toolkit and pipeline for genetic analyses of admixed populations (2024), published in Bioinformatics

Frequent collaborators in McDonnell's research include:

  • Nicholas B. Larson
  • Stephen N. Thibodeau
  • Daniel J. Schaid
  • Peter C. Harris
  • Rosalind A. Eeles

The primary venues where Shannon K. McDonnell publishes are diverse but center on medical and genetic research, with recurrent appearances in:

  • Journal of the American Society of Nephrology
  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Human Genetics and Genomics Advances
  • European Urology Oncology

Overall, Shannon K. McDonnell's scientific contributions span a range of genetic and medical studies focused on disease predisposition, particularly prostate cancer, and applied molecular and genetic techniques to improve understanding and potential clinical approaches across related fields of study.

Best Publications

  • REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants

    Nilah M M. Ioannidis;Joseph H H. Rothstein;Joseph H H. Rothstein;Vikas Pejaver;Sumit Middha

  • Efficacy of Bilateral Prophylactic Mastectomy in Women with a Family History of Breast Cancer

    L C Hartmann;D J Schaid;J E Woods;T P Crotty

  • Efficacy of Bilateral Prophylactic Mastectomy in BRCA1 and BRCA2 Gene Mutation Carriers

    Lynn C. Hartmann;Thomas A. Sellers;Daniel J. Schaid;Thomas S. Frank

  • Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

    Fredrick R. Schumacher;Ali Amin Al Olama;Sonja I. Berndt;Sara Benlloch

  • Microsatellite instability in colorectal cancer: different mutator phenotypes and the principal involvement of hMLH1.

    Stephen N. Thibodeau;Amy J. French;Julie M. Cunningham;David Tester

  • Incidence and distribution of parkinsonism in Olmsted County, Minnesota, 1976–1990

    James H. Bower;Demetrius M. Maraganore;Shannon K. McDonnell;Walter A. Rocca

  • Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

    Rosalind A. Eeles;Ali Amin Al Olama;Sara Benlloch;Edward J. Saunders

  • Evidence for a prostate cancer susceptibility locus on the X chromosome.

    Jianfeng Xu;Deborah Meyers;Diha Freije;Sarah Isaacs

  • Anxiety disorders and depressive disorders preceding Parkinson's disease: a case-control study.

    Mitsuru Shiba;James H. Bower;Demetrius M. Maraganore;Shannon K. McDonnell

  • Increased Risk for Cancer in Patients with the Peutz-Jeghers Syndrome

    Lisa A. Boardman;Stephen N. Thibodeau;Daniel J. Schaid;Noralane M. Lindor

  • A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

    Ali Amin Al Olama;Zsofia Kote-Jarai;Sonja I. Berndt;David V. Conti

  • Identification of seven new prostate cancer susceptibility loci through a genome-wide association study

    Rosalind A. Eeles;Zsofia Kote-Jarai;Ali Amin Al Olama;Graham G. Giles;Graham G. Giles

  • Incidence of progressive supranuclear palsy and multiple system atrophy in Olmsted County, Minnesota, 1976 to 1990

    James H. Bower;Demetrius M. Maraganore;Shannon K. McDonnell;Walter A. Rocca

  • Risk tables for parkinsonism and Parkinson's disease.

    Alexis Elbaz;James H Bower;Demetrius M Maraganore;Shannon K McDonnell

  • Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer

    Julius Gudmundsson;Patrick Sulem;Thorunn Rafnar;Jon T. Bergthorsson

  • Microsatellite Instability and 8p Allelic Imbalance in Stage B2 and C Colorectal Cancers

    Kevin C. Halling;Amy J. French;Shannon K. McDonnell;Lawrence J. Burgart

  • The frequency of hereditary defective mismatch repair in a prospective series of unselected colorectal carcinomas.

    Julie M. Cunningham;Cheong Yong Kim;Eric R. Christensen;David J. Tester

  • Long-term satisfaction and psychological and social function following bilateral prophylactic mastectomy.

    Marlene H. Frost;Daniel J. Schaid;Thomas A. Sellers;Jeffrey M. Slezak

  • Mutations in CHEK2 associated with prostate cancer risk.

    Xiangyang Dong;Liang Wang;Ken Taniguchi;Xianshu Wang

  • BRAF Mutations in Colon Cancer Are Not Likely Attributable to Defective DNA Mismatch Repair

    Liang Wang;Julie M. Cunningham;Jennifer L. Winters;Jennifer C. Guenther

Frequent Co-Authors

Daniel J. Schaid
Daniel J. Schaid Mayo Clinic
Janet L. Stanford
Janet L. Stanford Fred Hutchinson Cancer Research Center
Lisa A. Cannon-Albright
Lisa A. Cannon-Albright University of Utah
Graham G. Giles
Graham G. Giles University of Melbourne
Johanna Schleutker
Johanna Schleutker Turku University Hospital
Elaine A. Ostrander
Elaine A. Ostrander National Institutes of Health
David E. Neal
David E. Neal University of Cambridge
Rosalind A. Eeles
Rosalind A. Eeles Institute of Cancer Research
Henrik Grönberg
Henrik Grönberg Karolinska Institute

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