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Ricardo B. Maccioni

Ricardo B. Maccioni

Award Badge
Biology and Biochemistry
Chile
2026

D-Index & Metrics

Neuroscience

D-Index
61
Citations
12454
World Ranking
3697
National Ranking
4

Biology and Biochemistry

D-Index
62
Citations
12974
World Ranking
10852
National Ranking
10

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Chile Leader Award
  • 2025 - Research.com Biology and Biochemistry in Chile Leader Award

Overview

Ricardo B. Maccioni is affiliated with the University of Chile in Chile and has contributed extensively to research in medicine and neuroscience, with a particular focus on Alzheimer's disease. Their work encompasses a range of topics including Alzheimer's disease research and treatments, neuroinflammation and neurodegeneration mechanisms, tryptophan and brain disorders, cholinesterase and neurodegenerative diseases, dementia and cognitive impairment research, neurological disease mechanisms and treatments, and the role of medicinal plants in neuroprotection.

Maccioni has published a significant number of papers emphasizing multiple aspects of Alzheimer's disease and related neurological conditions. Some recent publications include:

  • New Frontiers in the Prevention, Diagnosis, and Treatment of Alzheimer's Disease (2021) in the Journal of Alzheimer s Disease
  • The Emerging Role of Nutraceuticals and Phytochemicals in the Prevention and Treatment of Alzheimer's Disease (2020) in the Journal of Alzheimer s Disease
  • Glucose metabolism and AD: evidence for a potential diabetes type 3 (2022) in Alzheimer s Research & Therapy
  • Revisiting the neuroinflammation hypothesis in Alzheimer's disease: a focus on the druggability of current targets (2023) in Frontiers in Pharmacology
  • Novel Nutraceutical Compounds in Alzheimer Prevention (2022) in Biomolecules

Their research contributions often explore interdisciplinary approaches combining molecular biology, physiology, neurology, and complementary medicine to understand neurological disorders. Their subfields of study primarily include physiology, neurology, molecular biology, complementary and alternative medicine, and endocrinology, diabetes, and metabolism.

Maccioni frequently collaborates with several researchers who have coauthored multiple publications, including:

  • Camila Calfío
  • Andrea González
  • Leonardo Guzmán-Martínez
  • Sandeep Kumar Singh
  • Leonel E. Rojo

Their work is published predominantly in the Journal of Alzheimer s Disease, which accounts for a majority of their articles. Other publication venues include Alzheimer's & Dementia, Alzheimer's Research & Therapy, Frontiers in Pharmacology, and Biomolecules.

Best Publications

  • Neuroinflammation as a Common Feature of Neurodegenerative Disorders.

    Leonardo Guzman-Martinez;Ricardo Benjamin Maccioni;Victor Andrade;Leonardo Patricio Navarrete

  • The molecular bases of Alzheimer's disease and other neurodegenerative disorders

    Ricardo B Maccioni;Juan P Muñoz;Luis Barbeito

  • Role of microtubule-associated proteins in the control of microtubule assembly

    R. B. Maccioni;V. Cambiazo

  • Neuroinflammation in the pathogenesis of Alzheimer's disease. A rational framework for the search of novel therapeutic approaches.

    Inelia Morales;Leonardo Guzmán-Martínez;Cristóbal Cerda-Troncoso;Gonzalo A. Farías

  • Interleukin-6 induces Alzheimer-type phosphorylation of tau protein by deregulating the cdk5/p35 pathway.

    Rodrigo A Quintanilla;Daniel I Orellana;Daniel I Orellana;Christian González-Billault;Christian González-Billault;Ricardo B Maccioni;Ricardo B Maccioni

  • Neuroinflammation: Implications for the Pathogenesis and Molecular Diagnosis of Alzheimer's Disease

    Leonel E. Rojo;Leonel E. Rojo;Jorge A. Fernández;Andrea A. Maccioni;José M. Jimenez

  • The revitalized tau hypothesis on Alzheimer's disease.

    Ricardo B. Maccioni;Gonzalo Farías;Inelia Morales;Leonardo Navarrete

  • Controlled proteolysis of tubulin by subtilisin: localization of the site for MAP2 interaction

    Luis Serrano;Jesus Avila;Ricardo B. Maccioni

  • Insulin Resistance and Alzheimers Disease: Molecular Links & Clinical Implications

    Karen F. Neumann;Leonel Rojo;Leonardo P. Navarrete;Gonzalo Farias

  • Inhibition of tau phosphorylating protein kinase cdk5 prevents β-amyloid-induced neuronal death

    Alejandra Alvarez;Rodrigo Toro;Alfredo Cáceres;Ricardo B Maccioni

  • The Role of Neuroimmunomodulation in Alzheimer's Disease

    Ricardo B. Maccioni;Ricardo B. Maccioni;Leonel E. Rojo;Leonel E. Rojo;Leonel E. Rojo;Jorge A. Fernández;Rodrigo O. Kuljis

  • Involvement of the carboxyl-terminal domain of tubulin in the regulation of its assembly

    L Serrano;J de la Torre;R B Maccioni;J Avila

  • Evidence for the Participation of the Neuron-Specific CDK5 Activator P35 during Laminin-Enhanced Axonal Growth

    Gabriela Paglini;Gustavo Pigino;Patricia Kunda;Gerardo Morfini

  • The protein kinase Cdk5

    Ricardo B. Maccioni;Carola Otth;Ilona I. Concha;Juan P. Muñoz

  • The protein kinase Cdk5. Structural aspects, roles in neurogenesis and involvement in Alzheimer's pathology.

    Ricardo B. Maccioni;Carola Otth;Ilona I. Concha;Juan P. Munoz

  • Tau protein binds to pericentromeric DNA: a putative role for nuclear tau in nucleolar organization

    Marcela K Sjöberg;Elena Shestakova;Zeyni Mansuroglu;Ricardo B Maccioni

  • Neuroimmunomodulation in the Pathogenesis of Alzheimer’s Disease

    Inelia Morales;Gonzalo Farías;Ricardo B. Maccioni

  • Tau oligomers and fibrils induce activation of microglial cells

    Inelia Morales;José M. Jiménez;Marcela Mancilla;Ricardo B. Maccioni

  • A Cdk5–p35 Stable Complex Is Involved in the β-Amyloid-Induced Deregulation of Cdk5 Activity in Hippocampal Neurons

    Alejandra Alvarez;Juan Pablo Muñoz;Ricardo B. Maccioni

  • Selective interaction of lansoprazole and astemizole with tau polymers: potential new clinical use in diagnosis of Alzheimer's disease.

    Leonel E. Rojo;Jans Alzate-Morales;Iván N. Saavedra;Peter Davies

  • AβPP induces cdk5-dependent tau hyperphosphorylation in transgenic mice Tg2576

    Carola Otth;Carola Otth;Ilona I. Concha;Ilona I. Concha;Thomas Arendt;Jens Stieler

Frequent Co-Authors

Jesús Avila
Jesús Avila Centro de Biología Molecular Severo Ochoa
Luis Serrano
Luis Serrano Centre for Genomic Regulation
Marco T. Núñez
Marco T. Núñez University of Chile
James T. Becker
James T. Becker University of Pittsburgh
Alfredo Cáceres
Alfredo Cáceres National Scientific and Technical Research Council
Patricia Muñoz
Patricia Muñoz Hospital General Universitario Gregorio Marañón
Oscar L. Lopez
Oscar L. Lopez University of Pittsburgh
Thomas Arendt
Thomas Arendt Leipzig University
Reinhard Schliebs
Reinhard Schliebs Leipzig University
Norberto Garcia-Cairasco
Norberto Garcia-Cairasco Universidade de São Paulo

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