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Thomas Arendt

Thomas Arendt

D-Index & Metrics

Neuroscience

D-Index
89
Citations
25503
World Ranking
1165
National Ranking
99

Overview

Thomas Arendt is affiliated with Leipzig University in Germany and has a research focus primarily in biochemistry, genetics, molecular biology, and medicine. Their work intersects several subfields including molecular biology, physiology, neurology, cellular and molecular neuroscience, and cell biology.

The scientist's research topics cover a range of areas in neuroscience and molecular medicine, such as Alzheimer's disease research and treatments, neuroscience and neuropharmacology research, RNA regulation and disease, Parkinson's disease mechanisms and treatments, sirtuins and resveratrol in medicine, endoplasmic reticulum stress and disease, and proteoglycans and glycosaminoglycans research.

Selected recent papers by Thomas Arendt include:

  • Superficial white matter imaging: Contrast mechanisms and whole-brain in vivo mapping, 2020, Science Advances
  • Cell specific quantitative iron mapping on brain slices by immuno-µPIXE in healthy elderly and Parkinson's disease, 2021, Acta Neuropathologica Communications
  • SIRT6-CBP-dependent nuclear Tau accumulation and its role in protein synthesis, 2021, Cell Reports
  • Caspase-cleaved tau is senescence-associated and induces a toxic gain of function by putting a brake on axonal transport, 2022, Molecular Psychiatry
  • Neurocan Contributes to Perineuronal Net Development, 2020, Neuroscience

Thomas Arendt frequently collaborates with several co-authors, including:

  • Uwe Ueberham
  • Markus Morawski
  • Max Holzer
  • Evgeniya Kirilina
  • Nikolaus Weiskopf

Regarding publication venues, Thomas Arendt's work has appeared repeatedly in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Acta Neuropathologica Communications
  • Molecular Psychiatry
  • Neuroscience
  • NeuroImage

Best Publications

  • The cholinergic system in aging and neuronal degeneration.

    Reinhard Schliebs;Thomas Arendt

  • Loss of neurons in the nucleus basalis of Meynert in Alzheimer's disease, paralysis agitans and Korsakoff's Disease.

    T Arendt;V Bigl;A Arendt;A Tennstedt

  • A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice

    Wolfgang Enard;Sabine Gehre;Kurt Hammerschmidt;Sabine M. Hölter

  • The significance of the cholinergic system in the brain during aging and in Alzheimer's disease.

    R. Schliebs;T. Arendt

  • Tau and tauopathies

    Thomas Arendt;Jens T. Stieler;Max Holzer

  • Synaptic degeneration in Alzheimer’s disease

    Thomas Arendt

  • Neuronal loss in different parts of the nucleus basalis is related to neuritic plaque formation in cortical target areas in alzheimer's disease

    T. Arendt;V. Bigl;A. Tennstedt;A. Arendt

  • Plastic Neuronal Remodeling Is Impaired in Patients with Alzheimer’s Disease Carrying Apolipoprotein ε4 Allele

    Thomas Arendt;Cornelia Schindler;Martina K. Brückner;Klaus Eschrich

  • Reversible paired helical filament-like phosphorylation of tau is an adaptive process associated with neuronal plasticity in hibernating animals.

    Thomas Arendt;Jens Stieler;Arjen M. Strijkstra;Roelof A. Hut

  • Changes in acetylcholinesterase and butyrylcholinesterase in Alzheimer's disease resemble embryonic development--a study of molecular forms.

    Thomas Arendt;Martina K. Brückner;Matthias Lange;Volker Bigl

  • Regional patterns of gene expression in human and chimpanzee brains.

    Philipp Khaitovich;Bjoern Muetzel;Xinwei She;Michael Lachmann

  • Cholinergic system and memory in the rat: effects of chronic ethanol, embryonic basal forebrain brain transplants and excitotoxic lesions of cholinergic basal forebrain projection system.

    T. Arendt;Y. Allen;R.M. Marchbanks;M.M. Schugens

  • Perineuronal nets potentially protect against oxidative stress

    Markus Morawski;Martina K. Brückner;Peter Riederer;Gert Brückner

  • Impact of cellular senescence signature on ageing research.

    Ewa Sikora;Thomas Arendt;Martin Bennett;Masashi Narita

  • Cholinergic-rich brain transplants reverse alcohol-induced memory deficits

    Thomas Arendt;Yvonne Allen;John Sinden;Markus M. Schugens

  • Aneuploidy and DNA Replication in the Normal Human Brain and Alzheimer's Disease

    Birgit Mosch;Markus Morawski;Anja Mittag;Dominik Lenz

  • Aberrant expression of NOS isoforms in Alzheimer's disease is structurally related to nitrotyrosine formation.

    Hans-Joachim Lüth;Gerald Münch;Thomas Arendt

  • Cortical areas abundant in extracellular matrix chondroitin sulphate proteoglycans are less affected by cytoskeletal changes in Alzheimer's disease.

    G. Brückner;D. Hausen;W. Härtig;M. Drlicek

  • Synaptic plasticity and cell cycle activation in neurons are alternative effector pathways: the 'Dr. Jekyll and Mr. Hyde concept' of Alzheimer's disease or the yin and yang of neuroplasticity.

    Thomas Arendt

  • Expression of endothelial and inducible NOS-isoforms is increased in Alzheimer's disease, in APP23 transgenic mice and after experimental brain lesion in rat : evidence for an induction by amyloid pathology

    Hans-Joachim Lüth;Max Holzer;Ulrich Gärtner;Matthias Staufenbiel

  • Crosslinking of α-synuclein by advanced glycation endproducts — an early pathophysiological step in Lewy body formation?

    G. Münch;H.J. Lüth;A. Wong;Th. Arendt

  • Loss of neurons in the rat basal forebrain cholinergic projection system after prolonged intake of ethanol.

    T Arendt;D Henning;J A Gray;R Marchbanks

Frequent Co-Authors

Markus Morawski
Markus Morawski Leipzig University
Wolfgang Härtig
Wolfgang Härtig Leipzig University
Volker Bigl
Volker Bigl Leipzig University
Nikolaus Weiskopf
Nikolaus Weiskopf Max Planck Society
Gert Brückner
Gert Brückner Leipzig University
Kurt Brauer
Kurt Brauer Leipzig University
Reinhard Schliebs
Reinhard Schliebs Leipzig University
Stefan Geyer
Stefan Geyer Max Planck Society
D. Yves von Cramon
D. Yves von Cramon Max Planck Institute for Human Cognitive and Brain Sciences
Svante Pääbo
Svante Pääbo Max Planck Institute for Evolutionary Anthropology

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