Subash Sad

Overview

Best Publications

• The expanding universe of T-cell subsets: Th1, Th2 and more

  Tim R. Mosmann;Subash Sad

  5402
  Citations

• Cytokine-induced differentiation of precursor mouse CD8+ T cells into cytotoxic CD8+ T cells secreting Th1 or Th2 cytokines

  Subash Sad;Rita Marcotte;Tim R. Mosmann

  899
  Citations

• Apoptotic vesicles crossprime CD8 T cells and protect against tuberculosis

  Florian Winau;Stephan Weber;Subash Sad;Juana de Diego

  525
  Citations

• Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium

  Nirmal Robinson;Scott McComb;Scott McComb;Rebecca Mulligan;Rebecca Mulligan;Rebecca Mulligan;Renu Dudani

  466
  Citations

• Single IL-2-secreting precursor CD4 T cell can develop into either Th1 or Th2 cytokine secretion phenotype.

  S Sad;T R Mosmann

  360
  Citations

• Functions of CD8 T-cell subsets secreting different cytokine patterns☆

  Tim R. Mosmann;Li Li;Subash Sad

  314
  Citations

• Targeting macrophage necroptosis for therapeutic and diagnostic interventions in atherosclerosis

  Denuja Karunakaran;Michele Geoffrion;Lihui Wei;Wei Gan

  250
  Citations

• Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages

  Scott McComb;Erin Cessford;Norah A. Alturki;Julie Joseph

  213
  Citations

• cIAP1 and cIAP2 limit macrophage necroptosis by inhibiting Rip1 and Rip3 activation

  S McComb;H H Cheung;H H Cheung;R G Korneluk;R G Korneluk;S Wang

  170
  Citations

• CD8Tc1 and Tc2 cells secrete distinct cytokine patterns in vitro and in vivo but induce similar inflammatory reactions.

  L Li;S Sad;D Kägi;T R Mosmann

  160
  Citations

• IL-15 regulates CD8+ T cell contraction during primary infection.

  Toshiki Yajima;Kazufumi Yoshihara;Kenji Nakazato;Shino Kumabe

  157
  Citations

• Multiple Mechanisms Compensate to Enhance Tumor-Protective CD8+ T Cell Response in the Long-Term Despite Poor CD8+ T Cell Priming Initially: Comparison Between an Acute Versus a Chronic Intracellular Bacterium Expressing a Model Antigen

  Renu Dudani;Yvan Chapdelaine;Henk van Faassen;Dean K. Smith

  143
  Citations

• Biochemical Engineering of Surface α2–8 Polysialic Acid for Immunotargeting Tumor Cells

  Tianmin Liu;Zhongwu Guo;Qingling Yang;Subash Sad

  138
  Citations

• Reducing the Stimulation of CD8+ T Cells during Infection with Intracellular Bacteria Promotes Differentiation Primarily into a Central (CD62LhighCD44high) Subset

  Henk van Faassen;Marsha Saldanha;Deanna Gilbertson;Renu Dudani

  137
  Citations

• Archaeosomes Induce Long-Term CD8+ Cytotoxic T Cell Response to Entrapped Soluble Protein by the Exogenous Cytosolic Pathway, in the Absence of CD4+ T Cell Help

  L Krishnan;S Sad;G B Patel;G D Sprott

  116
  Citations

• The Potent Adjuvant Activity of Archaeosomes Correlates to the Recruitment and Activation of Macrophages and Dendritic Cells In Vivo

  L Krishnan;S Sad;G B Patel;G D Sprott

  112
  Citations

• VEGF-Mediated Induction of PRD1-BF1/Blimp1 Expression Sensitizes Tumor Vasculature to Oncolytic Virus Infection

  Rozanne Arulanandam;Cory Batenchuk;Fernando A. Angarita;Kathryn Ottolino-Perry

  105
  Citations

• Interleukin (IL) 4, in the absence of antigen stimulation, induces an anergy-like state in differentiated CD8+ TC1 cells: loss of IL-2 synthesis and autonomous proliferation but retention of cytotoxicity and synthesis of other cytokines.

  Subash Sad;Tim R. Mosmann

  105
  Citations

• Perforin and Fas killing by CD8+ T cells limits their cytokine synthesis and proliferation.

  S Sad;D Kägi;T R Mosmann

  105
  Citations

• Cytotoxicity and weak CD40 ligand expression of CD8+ type 2 cytotoxic T cells restricts their potential B cell helper activity.

  Subash Sad;Subash Sad;Lakshmi Krishnan;R. Chris Bleackley;David Kägi

  98
  Citations