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Takashi Nishimura

Takashi Nishimura

D-Index & Metrics

Microbiology

D-Index
54
Citations
10178
World Ranking
3970
National Ranking
162

Overview

Takashi Nishimura is affiliated with the University of Tokyo in Japan and has contributed extensively to the field of medicine, with a specialized focus on hepatology. Their research encompasses over 400 publications, reflecting a consistent academic output primarily in clinical and translational studies related to liver diseases and oncology.

Their work spans several main fields of study including:

  • Medicine

Within this broad domain, Nishimura's subfields of study are:

  • Hepatology
  • Epidemiology
  • Oncology
  • Surgery
  • Pulmonary and Respiratory Medicine

The principal research topics covered by Nishimura include:

  • Hepatocellular Carcinoma Treatment and Prognosis
  • Liver Disease Diagnosis and Treatment
  • Liver Disease and Transplantation
  • Nutrition and Health in Aging
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Hepatitis C virus research
  • Hepatitis B Virus Studies

Nishimura's publications frequently appear in several specific academic journals, with notable contributions in:

  • Hepatology Research (18 publications)
  • In Vivo (15 publications)
  • Cancer Medicine (8 publications)
  • Oncology (8 publications)
  • Journal of Gastroenterology (5 publications)

Recent notable papers authored or co-authored by Nishimura cover clinical trials and therapeutic evaluations primarily concerning hepatocellular carcinoma and respiratory therapy. These include:

  • "Atezolizumab plus bevacizumab versus lenvatinib for unresectable hepatocellular carcinoma: a large real-life worldwide population" (2022, European Journal of Cancer)
  • "Home High-Flow Nasal Cannula Oxygen Therapy for Stable Hypercapnic COPD: A Randomized Clinical Trial" (2022, American Journal of Respiratory and Critical Care Medicine)
  • "Prognostic impact of C-reactive protein and alpha-fetoprotein in immunotherapy score in hepatocellular carcinoma patients treated with atezolizumab plus bevacizumab: a multicenter retrospective study" (2022, Hepatology International)
  • "Atezolizumab plus bevacizumab treatment for unresectable hepatocellular carcinoma: Early clinical experience" (2021, Cancer Reports)
  • "Therapeutic efficacy of atezolizumab plus bevacizumab treatment for unresectable hepatocellular carcinoma in patients with Child-Pugh class A or B liver function in real-world clinical practice" (2022, Hepatology Research)

Collaborations feature prominently in Nishimura's career, with frequent co-authors including:

  • Hiroko Iijima (107 joint publications)
  • Toshifumi Tada (69 joint publications)
  • Hirayuki Enomoto (66 joint publications)
  • Hidenori Toyoda (62 joint publications)
  • Masashi Hirooka (61 joint publications)

Best Publications

  • The Natural Killer T (NKT) Cell Ligand α-Galactosylceramide Demonstrates Its Immunopotentiating Effect by Inducing Interleukin (IL)-12 Production by Dendritic Cells and IL-12 Receptor Expression on NKT Cells

    Hidemitsu Kitamura;Kenji Iwakabe;Takashi Yahata;Shin-ichiro Nishimura

  • Distinct Role of Antigen-Specific T Helper Type 1 (Th1) and Th2 Cells in Tumor Eradication in Vivo

    Takashi Nishimura;Kenji Iwakabe;Masashi Sekimoto;Yasushi Ohmi

  • Role of vascular cell adhesion molecule 1/very late activation antigen 4 and intercellular adhesion molecule 1/lymphocyte function-associated antigen 1 interactions in antigen-induced eosinophil and T cell recruitment into the tissue.

    H Nakajima;H Sano;T Nishimura;S Yoshida

  • The interface between innate and acquired immunity: glycolipid antigen presentation by CD1d-expressing dendritic cells to NKT cells induces the differentiation of antigen-specific cytotoxic T lymphocytes.

    Takashi Nishimura;Hidemitsu Kitamura;Kenji Iwakabe;Takashi Yahata

  • The critical role of Th1-dominant immunity in tumor immunology

    Takashi Nishimura;Minoru Nakui;Marimo Sato;Kenji Iwakabe

  • Tumor‐infiltrating IL‐17‐producing γδ T cells support the progression of tumor by promoting angiogenesis

    Daiko Wakita;Kentaro Sumida;Yoichiro Iwakura;Hiroyoshi Nishikawa

  • Local radiation therapy inhibits tumor growth through the generation of tumor-specific CTL: its potentiation by combination with Th1 cell therapy.

    Tsuguhide Takeshima;Kenji Chamoto;Daiko Wakita;Takayuki Ohkuri

  • IL-6–dependent spontaneous proliferation is required for the induction of colitogenic IL-17–producing CD8+ T cells

    Masaki Tajima;Daiko Wakita;Daisuke Noguchi;Kenji Chamoto

  • α-Galactosylceramide Induces Early B-Cell Activation through IL-4 Production by NKT Cells

    Hidemitsu Kitamura;Akio Ohta;Akio Ohta;Masashi Sekimoto;Marimo Sato

  • The critical role of type‐1 innate and acquired immunity in tumor immunotherapy

    Hiroaki Ikeda;Kenji Chamoto;Takemasa Tsuji;Yoshinori Suzuki

  • Liposome-encapsulated CpG oligodeoxynucleotides as a potent adjuvant for inducing type 1 innate immunity

    Yoshinori Suzuki;Daiko Wakita;Kenji Chamoto;Yoshinori Narita

  • The restraint stress drives a shift in Th1/Th2 balance toward Th2-dominant immunity in mice

    Kenji Iwakabe;Masako Shimada;Akio Ohta;Takashi Yahata

  • Sonographic evaluation of the peripheral nerve in diabetic patients: the relationship between nerve conduction studies, echo intensity, and cross-sectional area.

    Tsuneo Watanabe;Hiroyasu Ito;Ayako Sekine;Yuriko Katano

  • Anti‐IL‐6 receptor mAb eliminates myeloid‐derived suppressor cells and inhibits tumor growth by enhancing T‐cell responses

    Kentaro Sumida;Daiko Wakita;Yoshinori Narita;Kazutaka Masuko

  • Generation of tumor-specific, HLA class I–restricted human Th1 and Tc1 cells by cell engineering with tumor peptide–specific T-cell receptor genes

    Takemasa Tsuji;Masaki Yasukawa;Junko Matsuzaki;Takayuki Ohkuri

  • 1α,25-Dihydroxyvitamin D3 and all-trans retinoic acid synergistically inhibit the differentiation and expansion of Th17 cells

    Utako Ikeda;Daiko Wakita;Takayuki Ohkuri;Kenji Chamoto

  • Murine NKT cells produce Th17 cytokine interleukin-22.

    Megumi Goto;Masao Murakawa;Kumiko Kadoshima-Yamaoka;Yoshitaka Tanaka

  • Anti-OX40 monoclonal antibody therapy in combination with radiotherapy results in therapeutic antitumor immunity to murine lung cancer

    Hiroshi Yokouchi;Koichi Yamazaki;Kenji Chamoto;Eiki Kikuchi

  • Immunomodulating effect of vitamin D3 derivatives on type-1 cellular immunity.

    Ikuo Imazeki;Junko Matsuzaki;Keiko Tsuji;Takashi Nishimura

  • Successful elimination of memory-type CD8+ T cell subsets by the administration of anti-Gr-1 monoclonal antibody in vivo

    Junko Matsuzaki;Takemasa Tsuji;Kenji Chamoto;Tsuguhide Takeshima

  • The interface between innate and acquired immunity: glycolipid′ antigen presentation by CD1d-expressing dendritic cells to′ NKT cells induces the differentiation of antigen-specific′ cytotoxic T lymphocytes.

    T. Nishimura;H. Kitamura;K. Iwakabe;T. Yahata

Frequent Co-Authors

Sonoko Habu
Sonoko Habu Juntendo University
Shin-Ichiro Nishimura
Shin-Ichiro Nishimura Hokkaido University
Yoichiro Iwakura
Yoichiro Iwakura Tokyo University of Science
Masaharu Nishimura
Masaharu Nishimura Hokkaido University
Hiroyoshi Nishikawa
Hiroyoshi Nishikawa Nagoya University
Hiroshi Shiku
Hiroshi Shiku Mie University
Hideo Yagita
Hideo Yagita Juntendo University
Toshio Kitamura
Toshio Kitamura University of Tokyo

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