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Biology and Biochemistry

D-Index
61
Citations
15059
World Ranking
11252
National Ranking
4871

Overview

Jan E. Carette is affiliated with Stanford University in the United States and has contributed extensively to the fields of medicine and biochemistry, genetics, and molecular biology. Their research spans several subfields, including molecular biology, infectious diseases, public health, environmental and occupational health, epidemiology, and cardiology and cardiovascular medicine.

The scientist has focused on a variety of topics in their research, notably:

  • Mosquito-borne diseases and control
  • CRISPR and genetic engineering
  • Viral infections and immunology research
  • SARS-CoV-2 and COVID-19 research
  • RNA and protein synthesis mechanisms
  • Viral gastroenteritis research and epidemiology
  • Interferon and immune responses

Jan E. Carette's publications are frequently found in prominent venues. The main journals and repositories for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell
  • PLoS Pathogens
  • Value in Health
  • Viruses

Recent notable papers authored or co-authored by Carette include:

  • Small RNAs are modified with N-glycans and displayed on the surface of living cells, 2021, Cell
  • Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses, 2020, Cell
  • Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions, 2021, Cell
  • Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection, 2022, Nature Genetics
  • The human disease gene LYSET is essential for lysosomal enzyme transport and viral infection, 2022, Science

The scientist collaborates frequently with other researchers. Their chief co-authors include:

  • Wenjie Qiao
  • James Zengel
  • Ryan A. Flynn
  • Yaw Shin Ooi
  • Carolyn R. Bertozzi

Best Publications

  • Ebola virus entry requires the cholesterol transporter Niemann–Pick C1

    Jan E Carette;Jan E Carette;Matthijs Raaben;Anthony C. Wong;Andrew S. Herbert

  • Gene essentiality and synthetic lethality in haploid human cells

    Vincent A. Blomen;Peter Májek;Lucas T. Jae;Johannes W. Bigenzahn

  • RIP3 induces apoptosis independent of pronecrotic kinase activity.

    Pratyusha Mandal;Scott B. Berger;Sirika Pillay;Kenta Moriwaki

  • Haploid Genetic Screens in Human Cells Identify Host Factors Used by Pathogens

    Jan E. Carette;Carla P. Guimaraes;Malini Varadarajan;Annie S. Park

  • Small RNAs are modified with N-glycans and displayed on the surface of living cells.

    Ryan A Flynn;Kayvon Pedram;Stacy A Malaker;Pedro J Batista

  • An essential receptor for adeno-associated virus infection

    S. Pillay;N. L. Meyer;A. S. Puschnik;O. Davulcu

  • Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens

    Caleb D. Marceau;Andreas S. Puschnik;Karim Majzoub;Yaw Shin Ooi

  • Ebola virus entry requires the host-programmed recognition of an intracellular receptor

    Emily Happy Miller;Gregor Obernosterer;Matthijs Raaben;Andrew S Herbert

  • Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses.

    Ruofan Wang;Camille R. Simoneau;Jessie Kulsuptrakul;Mehdi Bouhaddou

  • Deciphering the glycosylome of dystroglycanopathies using haploid screens for lassa virus entry.

    Lucas T. Jae;Matthijs Raaben;Moniek Riemersma;Ellen van Beusekom

  • Generation of iPSCs from cultured human malignant cells.

    Jan E. Carette;Jan Pruszak;Jan Pruszak;Malini Varadarajan;Vincent A. Blomen

  • Antigen presentation profiling reveals recognition of lymphoma immunoglobulin neoantigens

    Michael S. Khodadoust;Niclas Olsson;Lisa E. Wagar;Ole A.W. Haabeth

  • MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors

    Kivanç Birsoy;Tim Wang;Richard Possemato;Omer H Yilmaz

  • RNA-protein interaction detection in living cells

    Muthukumar Ramanathan;Karim Majzoub;Deepti S Rao;Poornima H Neela

  • Global gene disruption in human cells to assign genes to phenotypes by deep sequencing

    Jan E Carette;Carla P. Guimarães;Irene Wuethrich;Vincent A Blomen;Vincent A Blomen

  • Lipolysis-stimulated lipoprotein receptor (LSR) is the host receptor for the binary toxin Clostridium difficile transferase (CDT)

    Panagiotis Papatheodorou;Jan E. Carette;George W. Bell;Carsten Schwan

  • PLA2G16 represents a switch between entry and clearance of Picornaviridae

    Jacqueline Staring;Eleonore von Castelmur;Vincent A Blomen;Lisa G van den Hengel

  • Late endosomal transport and tethering are coupled processes controlled by RILP and the cholesterol sensor ORP1L.

    Rik van der Kant;Alexander Fish;Lennert Janssen;Hans Janssen

  • A CRISPR toolbox to study virus-host interactions

    Andreas S. Puschnik;Karim Majzoub;Yaw Shin Ooi;Jan E. Carette

  • Global gene disruption in human cells to assign genes to phenotypes

    Jan E Carette;Carla P Guimaraes;Irene Wuethrich;Vincent A Blomen

Frequent Co-Authors

Thijn R. Brummelkamp
Thijn R. Brummelkamp Antoni van Leeuwenhoek Hospital
Carolyn R. Bertozzi
Carolyn R. Bertozzi Stanford University
Hidde L. Ploegh
Hidde L. Ploegh Boston Children's Hospital
Harry B. Greenberg
Harry B. Greenberg Stanford University
Winald R. Gerritsen
Winald R. Gerritsen Radboud University
Joshua E. Elias
Joshua E. Elias Stanford University
Peter Sarnow
Peter Sarnow Stanford University
Paul A. Khavari
Paul A. Khavari Stanford University
Sean P. J. Whelan
Sean P. J. Whelan Washington University in St. Louis
Nevan J. Krogan
Nevan J. Krogan University of California, San Francisco

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