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Chemistry

D-Index
49
Citations
11128
World Ranking
14678
National Ranking
3751

Overview

James B. McAlpine is affiliated with the University of Illinois at Chicago in the United States. Their research focuses on areas within biochemistry, genetics, and molecular biology, with a significant contribution to medicine.

The main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Subfields where they have published extensively cover:

  • Molecular Biology
  • Pharmacology
  • Orthodontics
  • Analytical Chemistry
  • Biochemistry

Research topics addressed by James B. McAlpine span several key areas:

  • Natural product bioactivities and synthesis
  • Chromatography in Natural Products
  • Dental materials and restorations
  • Microbial Natural Products and Biosynthesis
  • Phytochemicals and Antioxidant Activities
  • Pharmacological Effects of Natural Compounds
  • Bioactive natural compounds

Frequent publication venues where their work appears include:

  • Journal of Natural Products
  • Dental Materials
  • The Journal of Organic Chemistry
  • Analytical Chemistry
  • Organic Letters

Frequent co-authors collaborating with James B. McAlpine are:

  • Guido F. Pauli
  • Shao-Nong Chen
  • Ana K. Bedran-Russo
  • David C. Lankin
  • Mariana Reis

Recent publications illustrate the scope and diversity of their work. These include:

  • Antimycobacterial Rufomycin Analogues from Streptomyces atratus Strain MJM3502, 2020, Journal of Natural Products
  • Quantum mechanical NMR full spin analysis in pharmaceutical identity testing and quality control, 2020, Journal of Pharmaceutical and Biomedical Analysis
  • Unveiling structure-activity relationships of proanthocyanidins with dentin collagen, 2021, Dental Materials
  • Rufomycins or Ilamycins: Naming Clarifications and Definitive Structural Assignments, 2021, Journal of Natural Products
  • Tri- and Tetrameric Proanthocyanidins with Dentin Bioactivities from Pinus massoniana, 2020, The Journal of Organic Chemistry

Best Publications

  • Modular organization of genes required for complex polyketide biosynthesis.

    Stefano Donadio;Michael J. Staver;James B. McAlpine;Susan J. Swanson

  • Natural Deep Eutectic Solvents: Properties, Applications, and Perspectives.

    Yang Liu;J. Brent Friesen;James B. McAlpine;David C. Lankin

  • Importance of Purity Evaluation and the Potential of Quantitative 1H NMR as a Purity Assay

    Guido F. Pauli;Shao Nong Chen;Charlotte Simmler;David C. Lankin

  • Universal quantitative NMR analysis of complex natural samples

    Charlotte Simmler;José G. Napolitano;James B. McAlpine;Shao Nong Chen

  • Dentin biomodification: strategies, renewable resources and clinical applications

    Anakarina B. Bedran-Russo;Guido F. Pauli;Shaonong Chen;James B. McAlpine

  • Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.

    James B. McAlpine;Brian O. Bachmann;Mahmood Piraee;Steve Tremblay

  • An erythromycin analog produced by reprogramming of polyketide synthesis.

    Stefano Donadio;James B. McAlpine;Paul J. Sheldon;Marianna Jackson

  • Countercurrent Separation of Natural Products: An Update.

    J. Brent Friesen;James B. McAlpine;Shao Nong Chen;Guido F. Pauli

  • Can Invalid Bioactives Undermine Natural Product-Based Drug Discovery?

    Jonathan Bisson;James B. McAlpine;J. Brent Friesen;Shao-Nong Chen

  • Drug discovery from natural products

    Unknown

  • The Cyclic Peptide Ecumicin Targeting ClpC1 Is Active against Mycobacterium tuberculosis In Vivo

    Wei Gao;Jin Yong Kim;Jeffrey R. Anderson;Tatos Akopian

  • Molecular basis for chloronium-mediated meroterpene cyclization: cloning, sequencing, and heterologous expression of the napyradiomycin biosynthetic gene cluster.

    Jaclyn M. Winter;Michelle C. Moffitt;Emmanuel Zazopoulos;James B. McAlpine

  • A colorimetric microassay for the detection of agents that interact with DNA.

    Neal S. Burres;Andrea Frigo;Ronald R. Rasmussen;James B. McAlpine

  • Isolation, purification, and characterization of immunosuppressive compounds from tripterygium: triptolide and tripdiolide.

    Wen Zhen Gu;Randal Chen;Sydney Brandwein;James McAlpine

  • Galloyl moieties enhance the dentin biomodification potential of plant-derived catechins.

    Cristina M P Vidal;Thaiane R. Aguiar;Rasika Phansalkar;James B. McAlpine

  • Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.

    Arjun H. Banskota;James B. McAlpine;Dan Sørensen;Ashraf Ibrahim

  • 5-N-acetylardeemin, a novel heterocyclic compound which reverses multiple drug resistance in tumor cells. II. Isolation and elucidation of the structure of 5-N-acetylardeemin and two congeners.

    Jill E. Hochlowski;Mark M. Mullally;Stephen G. Spanton;David N. Whittern

  • Pacidamycins, a novel series of antibiotics with anti-Pseudomonas aeruginosa activity. II. Isolation and structural elucidation.

    Randal H. Chen;Alexander M. Buko;David N. Whittern;James B. Mcalpine

  • 5-N-acetylardeemin, a novel heterocyclic compound which reverses multiple drug resistance in tumor cells. I. Taxonomy and fermentation of the producing organism and biological activity.

    James P. Karwowski;Marianna Jackson;Ronald R. Rasmussen;Patrick E. Humphrey

  • The Value of Universally Available Raw NMR Data for Transparency, Reproducibility, and Integrity in Natural Product Research

    James B. McAlpine;Shao Nong Chen;Andrei Kutateladze;John B. Macmillan

  • HiFSA Fingerprinting Applied to Isomers with Near-Identical NMR Spectra: The Silybin/Isosilybin Case

    José G. Napolitano;David C. Lankin;Tyler N. Graf;J. Brent Friesen;J. Brent Friesen

  • Biosynthesis of the erythromycin macrolactone and a rational approach for producing hybrid macrolides.

    Stefano Donadio;Michael J. Staver;James B. McAlpine;Susan J. Swanson

  • Dentin Biomodification Potential Depends on Polyphenol Source

    T. R. Aguiar;C. M P Vidal;R. S. Phansalkar;I. Todorova

  • Essential Parameters for Structural Analysis and Dereplication by 1H NMR Spectroscopy

    Guido F. Pauli;Shao-Nong Chen;David C. Lankin;Jonathan Bisson

Frequent Co-Authors

Guido F. Pauli
Guido F. Pauli University of Illinois at Chicago
Shao-Nong Chen
Shao-Nong Chen University of Illinois at Chicago
Scott G. Franzblau
Scott G. Franzblau University of Illinois at Chicago
Bradley S. Moore
Bradley S. Moore University of California, San Diego
Lester A. Mitscher
Lester A. Mitscher University of Kansas
Richard B. van Breemen
Richard B. van Breemen Oregon State University
Ashraf S. Ibrahim
Ashraf S. Ibrahim University of California, Los Angeles
Nicholas H. Oberlies
Nicholas H. Oberlies University of North Carolina at Greensboro
Dean J. Tantillo
Dean J. Tantillo University of California, Davis
William H. Gerwick
William H. Gerwick University of California, San Diego

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