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Lester A. Mitscher

Lester A. Mitscher

D-Index & Metrics

Chemistry

D-Index
41
Citations
7679
World Ranking
17698
National Ranking
4320

Research.com Recognitions

  • 1995 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Lester A. Mitscher was affiliated with the University of Kansas in the United States during their academic career. Their research focused primarily within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine.

The scientist's work covered several key subfields, including Molecular Biology, Infectious Diseases, Epidemiology, Organic Chemistry, and Radiology, Nuclear Medicine and Imaging.

Mitscher's research topics spanned diverse areas such as:

  • Tuberculosis Research and Epidemiology
  • Mycobacterium research and diagnosis
  • Phenothiazines and Benzothiazines Synthesis and Activities
  • Chemical Synthesis and Analysis
  • Click Chemistry and Applications
  • Monoclonal and Polyclonal Antibodies Research
  • Bioactive natural compounds

Their notable recent publications include:

  • Novel Cephalosporins Selectively Active on Nonreplicating Mycobacterium tuberculosis, 2020, published in OPAL (Open@LaTrobe) (La Trobe University)
  • Combinatorial Chemistry and Its Associated Technologies, 2021, published in Burger's Medicinal Chemistry and Drug Discovery
  • Structure-Activity Relationship Among the Antibacterial Pterocarpans from African Erythrina Species: A Review, 2024, published in Tropical Journal of Phytochemistry and Pharmaceutical Sciences

Frequent coauthors with whom Mitscher collaborated include:

  • Jeffrey Aubé
  • Ben K. Gold
  • Robert J. Smith
  • Quyen T. Nguyen
  • Julia Link Roberts

Publication venues where Mitscher most frequently contributed were:

  • OPAL (Open@LaTrobe) (La Trobe University)
  • Burger's Medicinal Chemistry and Drug Discovery
  • Tropical Journal of Phytochemistry and Pharmaceutical Sciences

Lester A. Mitscher received recognition as a Fellow of the American Association for the Advancement of Science (AAAS) in 1995.

Best Publications

  • Bacterial topoisomerase inhibitors: quinolone and pyridone antibacterial agents.

    Lester A. Mitscher

  • Glossary of terms used in medicinal chemistry (IUPAC Recommendations 1998)

    C. G. Wermuth;C. R. Ganellin;P. Lindberg;L. A. Mitscher

  • Mechanism of inhibition of DNA gyrase by quinolone antibacterials: a cooperative drug--DNA binding model.

    Linus L. Shen;Lester A. Mitscher;Padam N. Sharma;T. J. O'Donnell

  • The Organic Chemistry of Drug Synthesis

    Daniel Lednicer;Lester A. Mitscher

  • The 2‐pyridone antibacterial agents: bacterial topoisomerase inhibitors

    Qun Li;Lester A. Mitscher;Linus L. Shen

  • Antimicrobial Agents from Higher Plants

    Unknown

  • Chemoprotection: a review of the potential therapeutic antioxidant properties of green tea (Camellia sinensis) and certain of its constituents.

    Lester A. Mitscher;Michel Jung;Delbert Shankel;Jin-Hui Dou

  • Glossary of terms used in medicinal chemistry

    CG Wermuth;CR Ganellin;P Lindberg;LA Mitscher

  • Hydrophobic collapse of taxol and taxotere solution conformations in mixtures of water and organic solvent

    D. G. Vander Velde;G. I. Georg;G. L. Grunewald;C. W. Gunn

  • The chemistry of the tetracycline antibiotics

    Lester A. Mitscher

  • Antimicrobial agents from higher plants. Antimicrobial isoflavanoids and related substances from Glycyrrhiza glabra L. var. typica.

    Lester A. Mitscher;Young Han Park;Donna Clark;Jack L. Beal

  • Streptonigrin and lavendamycin partial structures. Probes for the minimum, potent pharmacophore of streptonigrin, lavendamycin, and synthetic quinoline-5,8-diones.

    Dale L. Boger;Masami Yasuda;Lester A. Mitscher;Steven D. Drake

  • Natural antimutagenic agents.

    Lester A. Mitscher;Hanumaiah Telikepalli;Eva McGhee;Delbert M. Shankel

  • Chiral DNA gyrase inhibitors. 2. Asymmetric synthesis and biological activity of the enantiomers of 9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H- pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid (ofloxacin).

    Lester A. Mitscher;Padam N. Sharma;Daniel T. W. Chu;Linus L. Shen

  • A Convenient Method for the Control of Selective Ozonizations of Olefins

    Tarik Veysoglu;Lester A. Mitscher;John K. Swayze

  • Antimicrobial agents from higher plants. Antimicrobial agents from Peganum harmala seeds

    A. Al-Shamma;S. Drake;D. L. Flynn;L. A. Mitscher

  • Glossary of terms used in medicinal chemistry (IUPAC recommendations 1997)

    CG Wermuth;CR Ganellin;P Lindberg;LA Mitscher

  • Amorfrutin A and B, bibenzyl antimicrobial agents from Amorpha fruticosa

    Lester A. Mitscher;Young Han Park;Ali Alshamma;P.Bryan Hudson

  • Umbelliferone Analogues and Their Potential to Inhibit Benzo(a)pyrene- and Hydrogen Peroxide-Induced Mutations

    Segaran P. Pillai;Sanjay R. Menon;Lester A. Mitscher;Christine A. Pillai

  • A search for novel chemotherapy against tuberculosis amongst natural products

    Lester A. Mitscher;William R. Baker

  • The Structural Characterization of Tetrangomycin and Tetrangulol

    Unknown

  • Antitubercular Natural Products: Berberine from the Roots of Commercial Hydrastis canadensis Powder. Isolation of Inactive 8-Oxotetrahydrothalifendine, Canadine, β-Hydrastine, and Two New Quinic Acid Esters, Hycandinic Acid Esters-1 and -2

    Elmer J. Gentry;Hanuman B. Jampani;Ali Keshavarz-Shokri;Martha D. Morton

  • The search for orally active medications through combinatorial chemistry

    Robert A. Fecik;Kristine E. Frank;Elmer J. Gentry;Sanjay R. Menon

  • Scaffold-based design and synthesis of potent N-type calcium channel blockers.

    Gerald W. Zamponi;Zhong-Ping Feng;Lingyun Zhang;Hossein Pajouhesh

  • FORTIMICINS A AND B, NEW AMINOGLYCOSIDE ANTIBIOTICS

    Richard S. Egan;Ruth S. Stanaszek;Momir Cirovic;Sandra L. Mueller

Frequent Co-Authors

Gunda I. Georg
Gunda I. Georg University of Minnesota
Jeffrey Aubé
Jeffrey Aubé University of North Carolina at Chapel Hill
Gerald W. Zamponi
Gerald W. Zamponi University of Calgary
James B. McAlpine
James B. McAlpine University of Illinois at Chicago
Terrance P. Snutch
Terrance P. Snutch University of British Columbia
Dale L. Boger
Dale L. Boger Scripps Research Institute
Berl R. Oakley
Berl R. Oakley University of Kansas
Todd W. Vanderah
Todd W. Vanderah University of Arizona
David Dolphin
David Dolphin University of British Columbia
Frank Porreca
Frank Porreca University of Arizona

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