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D-Index & Metrics

Chemistry

D-Index
67
Citations
14099
World Ranking
7018
National Ranking
2087

Research.com Recognitions

  • 2012 - Fellow of the American Chemical Society
  • 2004 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1993 - Fellow of Alfred P. Sloan Foundation

Overview

Jeffrey Aubé is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with substantial contributions to Molecular Biology, Immunology, Organic Chemistry, Cellular and Molecular Neuroscience, and Infectious Diseases.

The scientist's work addresses several main topics including RNA Research and Splicing, RNA modifications and cancer, Immune Cell Function and Interaction, RNA and protein synthesis mechanisms, T-cell and B-cell Immunology, Neuropeptides and Animal Physiology, and Tuberculosis Research and Epidemiology.

Among the recent papers authored or coauthored by Jeffrey Aubé are:

  • HFIP in Organic Synthesis, 2022, Chemical Reviews
  • Targeting the interaction between RNA-binding protein HuR and FOXQ1 suppresses breast cancer invasion and metastasis, 2020, Communications Biology
  • An RNA-Binding Protein, Hu-antigen R, in Pancreatic Cancer Epithelial to Mesenchymal Transition, Metastasis, and Cancer Stem Cells, 2020, Molecular Cancer Therapeutics
  • SHAPE-enabled fragment-based ligand discovery for RNA, 2022, Proceedings of the National Academy of Sciences
  • Single-Cell Transcriptional Profiling Reveals Signatures of Helper, Effector, and Regulatory MAIT Cells during Homeostasis and Activation, 2022, The Journal of Immunology

The frequent coauthors associated with this scientist include Kelin Li, Kevin J. Frankowski, Xiaoqing Wu, Lanjing Wei, and Liang Xu. These collaborations indicate an active engagement in multidisciplinary scientific networks.

Jeffrey Aubé has published frequently in venues such as bioRxiv (Cold Spring Harbor Laboratory), UNC Libraries, Cancer Research, Journal of Medicinal Chemistry, and Proceedings of the National Academy of Sciences, reflecting a broad dissemination of research across high-impact platforms.

The scientist has been recognized with fellowships including Fellow of the American Chemical Society (2012), Fellow of the American Association for the Advancement of Science (AAAS) (2004), and Fellow of the Alfred P. Sloan Foundation (1993).

Best Publications

  • HFIP in Organic Synthesis.

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  • MAIT cells are imprinted by the microbiota in early life and promote tissue repair

    Michael G. Constantinides;Verena M. Link;Samira Tamoutounour;Andrea C. Wong

  • The internal quaternary ammonium receptor site of Shaker potassium channels

    Kathleen L. Choi;Craig Mossman;Jeffrey Aubé;Gary Yellen

  • Improvement of oral peptide bioavailability: Peptidomimetics and prodrug strategies

    Giovanni M. Pauletti;Giovanni M. Pauletti;Sanjeev Gangwar;Teruna J. Siahaan;Jeffrey Aubé

  • Intramolecular Schmidt Reaction of Alkyl Azides

    Jeffrey Aube;Gregory L. Milligan

  • Chemistry of Bridged Lactams and Related Heterocycles

    Michal Szostak;Jeffrey Aubé

  • Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria

    Tarsis F. Brust;Jenny Morgenweck;Susy A. Kim;Jamie H. Rose

  • Intramolecular Schmidt Reactions of Alkyl Azides with Ketones: Scope and Stereochemical Studies

    Gregory L. Milligan;Craig J. Mossman;Jeffrey Aube

  • Tumor suppressor TET2 promotes cancer immunity and immunotherapy efficacy

    Yan-ping Xu;Lei Lv;Ying Liu;Matthew D. Smith

  • Characterization of a Cdc42 protein inhibitor and its use as a molecular probe.

    Lin Hong;S. Ray Kenney;Genevieve K. Phillips;Denise S. Simpson

  • First Asymmetric Total Synthesis of (+)-Sparteine

    Brenton T. Smith;John A. Wendt;Jeffrey Aube

  • Advancing Biological Understanding and Therapeutics Discovery with Small Molecule Probes

    Stuart L. Schreiber;Stuart L. Schreiber;Joanne D. Kotz;Min Li;Min Li;Jeffrey Aubé

  • Development of Functionally Selective, Small Molecule Agonists at Kappa Opioid Receptors

    Lei Zhou;Kimberly M. Lovell;Kevin J. Frankowski;Stephen R. Slauson

  • Identification and validation of novel small molecule disruptors of HuR-mRNA interaction.

    Xiaoqing Wu;Lan Lan;David Michael Wilson;Rebecca T. Marquez

  • Intramolecular Friedel–Crafts Acylation Reaction Promoted by 1,1,1,3,3,3-Hexafluoro-2-propanol

    Hashim F. Motiwala;Rakesh H. Vekariya;Jeffrey Aubé

  • Syntheses of the Stemona Alkaloids (±)-Stenine, (±)-Neostenine, and (±)-13-Epineostenine Using a Stereodivergent Diels–Alder/Azido-Schmidt Reaction

    Kevin J. Frankowski;Jennifer E. Golden;Yibin Zeng;Yao Lei

  • Reactions of Alkyl Azides and Ketones as Mediated by Lewis Acids: Schmidt and Mannich Reactions Using Azide Precursors

    Pankaj Desai;Klaas Schildknegt;Konstantinos A. Agrios;Craig Mossman

  • One-Step Conversion of Aldehydes to Oxazolines and 5,6-Dihydro-4H-1,3-oxazines Using 1,2- and 1,3-Azido Alcohols

    Jennifer G. Badiang;Jeffrey Aubé

  • Regiocontrol in an Intramolecular Schmidt Reaction: Total Synthesis of (+)-Aspidospermidine

    Rajesh Iyengar;Klaas Schildknegt;Jeffrey Aubé

  • Natural product (−)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1

    Lan Lan;Carl Appelman;Amber Rae Smith;Jia Yu;Jia Yu

  • Revisiting a classic approach to the Aspidosperma alkaloids: an intramolecular Schmidt reaction mediated synthesis of (+)-aspidospermidine.

    Rajesh Iyengar;Klaas Schildknegt;Martha Morton;Jeffrey Aubé

Frequent Co-Authors

Larry A. Sklar
Larry A. Sklar University of New Mexico
Angela Wandinger-Ness
Angela Wandinger-Ness University of New Mexico
Michal Szostak
Michal Szostak Rutgers, The State University of New Jersey
Marc Ferrer
Marc Ferrer National Institutes of Health
Fusao Takusagawa
Fusao Takusagawa University of Kansas
Victor W. Day
Victor W. Day University of Kansas
Michael S. Glickman
Michael S. Glickman Memorial Sloan Kettering Cancer Center
Carl Nathan
Carl Nathan Cornell University
Min Li
Min Li Chinese Academy of Sciences
Lester A. Mitscher
Lester A. Mitscher University of Kansas

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