Jean-Marie Ghuysen

Research.com Recognitions

• 2023 - Research.com Biology and Biochemistry in Belgium Leader Award
• 1989 - Canada Gairdner International Award
• Member of the European Molecular Biology Organization (EMBO)
• Member of the European Molecular Biology Organization (EMBO)
• Member of the European Molecular Biology Organization (EMBO)

Overview

Best Publications

• A standard numbering scheme for the class A beta-lactamases.

  R. P. Ambler;A. F. W. Coulson;Jean-Marie Frère;Jean-Marie Ghuysen

  1580
  Citations

• Multimodular Penicillin-Binding Proteins: An Enigmatic Family of Orthologs and Paralogs

  Colette Goffin;Jean-Marie Ghuysen

  853
  Citations

• Serine beta-lactamases and penicillin-binding proteins.

  Jean-Marie Ghuysen

  844
  Citations

• Bacterial cell wall

  Jean-Marie Ghuysen;CJ Knill;JF Kennedy;R Hakenbeck

  707
  Citations

• Use of bacteriolytic enzymes in determination of wall structure and their role in cell metabolism.

  Jean-Marie Ghuysen

  644
  Citations

• Enzymes that degrade bacterial cell walls

  Jean-Marie Ghuysen;Donald J. Tipper;Jack L. Strominger

  637
  Citations

• The active-site-serine penicillin-recognizing enzymes as members of the Streptomyces R61 DD-peptidase family.

  B Joris;J M Ghuysen;G Dive;A Renard

  407
  Citations

• Mechanisms of enzymatic bacteriaolysis. Cell walls of bacteri are solubilized by action of either specific carbohydrases or specific peptidases.

  Jack L. Strominger;Jean-Marie Ghuysen

  332
  Citations

• On the origin of bacterial resistance to penicillin: comparison of a beta-lactamase and a penicillin target

  Judith A. Kelly;Otto Dideberg;Paulette Charlier;Jean-Pierre Wery

  294
  Citations

• Biochemistry and comparative genomics of SxxK superfamily acyltransferases offer a clue to the mycobacterial paradox: presence of penicillin-susceptible target proteins versus lack of efficiency of penicillin as therapeutic agent.

  Colette Goffin;Jean-Marie Ghuysen

  274
  Citations

• Molecular structures of penicillin-binding proteins and β-lactamases

  Jean-Marie Ghuysen

  254
  Citations

• A quasi-Newton algorithm for first-order saddle-point location

  Patrick Culot;Georges Dive;Van Hen Nguyen;Jean-Marie Ghuysen

  248
  Citations

• The catalytic, glycosyl transferase and acyl transferase modules of the cell wall peptidoglycan-polymerizing penicillin-binding protein 1b of Escherichia coli.

  Mohammed Terrak;Tushar K. Ghosh;Jean van Heijenoort;Jozef Van Beeumen

  241
  Citations

• Mechanism of acyl transfer by the class A serine β-lactamase of Streptomyces albus G

  Josette Lamotte-Brasseur;Georges Dive;Otto Dideberg;Paulette Charlier

  230
  Citations

• Comparison of the sequences of class A beta-lactamases and of the secondary structure elements of penicillin-recognizing proteins.

  Bernard Joris;P. Ledent;O. Dideberg;E. Fonze

  228
  Citations

• Modular design of the Enterococcus hirae muramidase-2 and Streptococcus faecalis autolysin

  Bernard Joris;Serge Englebert;Chien-Peng Chu;Reiko Kariyama

  211
  Citations

• STRUCTURE OF THE CELL WALL OF STAPHYLOCOCCUS AUREUS, STRAIN COPENHAGEN. I. PREPARATION OF FRAGMENTS BY ENZYMATIC HYDROLYSIS.

  Jean-Marie Ghuysen;Jack L. Strominger

  208
  Citations

• Occurrence of D-alanyl-(D)-meso-diaminopimelic acid and meso-diaminopimelyl-meso-diaminopimelic acid interpeptide linkages in the peptidoglycan of Mycobacteria.

  Juana Wietzerbin;Bhupsh C. Das;Jean-François Petit;Edgar Lederer

  193
  Citations

• The crystal structure of the β-lactamase of Streptomyces albus G at 0.3 nm resolution

  Otto Dideberg;Paulette Charlier;Jean-Paul Wery;Philippe Dehottay

  190
  Citations

• STRUCTURE OF THE CELL WALL OF STAPHYLOCOCCUS AUREUS, STRAIN COPENHAGEN. II. SEPARATION AND STRUCTURE OF DISACCHARIDES.

  Jean-Marie Ghuysen;Jack L. Strominger

  183
  Citations