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Luca Agnelli

Luca Agnelli

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
6483
World Ranking
17373
National Ranking
552

Overview

Luca Agnelli is affiliated with the University of Milan in Italy and has an extensive publication record primarily focused on medical and molecular biology research. Their work spans a diverse range of topics in oncology, hematology, and cancer genomics, reflecting a multidisciplinary approach to understanding and treating cancer.

The researcher has published papers in notable journals such as Blood, Annals of Oncology, Frontiers in Oncology, Journal of Clinical Oncology, and ESMO Open. These venues indicate a consistent engagement with clinical and translational research relevant to cancer biology and therapy.

Some of the recent papers by Luca Agnelli include:

  • Revealing the Impact of Structural Variants in Multiple Myeloma, 2020, Blood Cancer Discovery
  • Myeloma Cells Deplete Bone Marrow Glutamine and Inhibit Osteoblast Differentiation Limiting Asparagine Availability, 2020, Cancers
  • Tremelimumab and durvalumab as neoadjuvant or non-operative management strategy of patients with microsatellite instability-high resectable gastric or gastroesophageal junction adenocarcinoma: the INFINITY study by GONO, 2024, Annals of Oncology
  • Molecular Tumor Board as a Clinical Tool for Converting Molecular Data Into Real-World Patient Care, 2023, JCO Precision Oncology
  • Monocytes in leukapheresis products affect the outcome of CD19-targeted CAR T-cell therapy in patients with lymphoma, 2024, Blood Advances

Their frequent coauthors include:

  • Giancarlo Pruneri
  • Filippo de Braud
  • Daniele Lorenzini
  • Andrea Vingiani
  • Elena Tamborini

Luca Agnelli's research primarily spans the broad fields of Medicine and Biochemistry, Genetics and Molecular Biology. Within these fields, they focus on subfields such as:

  • Molecular Biology
  • Cancer Research
  • Oncology
  • Pulmonary and Respiratory Medicine
  • Hematology

The main topics of their work include:

  • Cancer Genomics and Diagnostics
  • Multiple Myeloma Research and Treatments
  • Lung Cancer Treatments and Mutations
  • Chronic Lymphocytic Leukemia Research
  • Advanced Breast Cancer Therapies
  • Lymphoma Diagnosis and Treatment
  • Ubiquitin and proteasome pathways

Best Publications

  • Rescue of Hippo coactivator YAP1 triggers DNA damage-induced apoptosis in hematological cancers

    Francesca Cottini;Teru Hideshima;Chunxiao Xu;Martin Sattler

  • Identification of microRNA expression patterns and definition of a microRNA/mRNA regulatory network in distinct molecular groups of multiple myeloma

    Marta Lionetti;Marta Biasiolo;Luca Agnelli;Katia Todoerti

  • Drugging the lncRNA MALAT1 via LNA gapmeR ASO inhibits gene expression of proteasome subunits and triggers anti-multiple myeloma activity.

    Nicola Amodio;Maria Angelica Stamato;Giada Juli;Eugenio Morelli

  • Functional validation of the anaplastic lymphoma kinase signature identifies CEBPB and Bcl2A1 as critical target genes

    Roberto Piva;Elisa Pellegrino;Michela Mattioli;Luca Agnelli

  • A SNP microarray and FISH-based procedure to detect allelic imbalances in multiple myeloma: an integrated genomics approach reveals a wide gene dosage effect.

    Luca Agnelli;Laura Mosca;Sonia Fabris;Marta Lionetti

  • Molecular Classification of Multiple Myeloma: A Distinct Transcriptional Profile Characterizes Patients Expressing CCND1 and Negative for 14q32 Translocations

    Luca Agnelli;Silvio Bicciato;Michela Mattioli;Sonia Fabris

  • Dependence on glutamine uptake and glutamine addiction characterize myeloma cells: a new attractive target

    Marina Bolzoni;Martina Chiu;Fabrizio Accardi;Rosanna Vescovini

  • Gene expression profiling of plasma cell dyscrasias reveals molecular patterns associated with distinct IGH translocations in multiple myeloma.

    Michela Mattioli;Luca Agnelli;Sonia Fabris;Luca Baldini

  • Gene Expression Profiling Uncovers Molecular Classifiers for the Recognition of Anaplastic Large-Cell Lymphoma Within Peripheral T-Cell Neoplasms

    Roberto Piva;Luca Agnelli;Elisa Pellegrino;Katia Todoerti

  • An integrative genomic approach reveals coordinated expression of intronic miR-335, miR-342, and miR-561 with deregulated host genes in multiple myeloma.

    Domenica Ronchetti;Marta Lionetti;Laura Mosca;Luca Agnelli

  • Hypoxia-inducible factor (HIF)-1α suppression in myeloma cells blocks tumoral growth in vivo inhibiting angiogenesis and bone destruction

    P Storti;M Bolzoni;G Donofrio;I Airoldi

  • Increased osteocyte death in multiple myeloma patients: role in myeloma-induced osteoclast formation

    N Giuliani;M Ferretti;M Bolzoni;P Storti

  • Identification of a 3-gene model as a powerful diagnostic tool for the recognition of ALK-negative anaplastic large-cell lymphoma

    Luca Agnelli;Elisabetta Mereu;Elisa Pellegrino;Tania Limongi

  • Identification of a new subclass of ALK-negative ALCL expressing aberrant levels of ERBB4 transcripts

    Irene Scarfò;Elisa Pellegrino;Elisabetta Mereu;Ivo Kwee

  • Long non-coding RNA NEAT1 targeting impairs the DNA repair machinery and triggers anti-tumor activity in multiple myeloma.

    Elisa Taiana;Vanessa Favasuli;Domenica Ronchetti;Katia Todoerti

  • Biological and Clinical Relevance of miRNA Expression Signatures in Primary Plasma Cell Leukemia

    Marta Lionetti;Pellegrino Musto;Maria Teresa Di Martino;Sonia Fabris

  • Revealing the impact of structural variants in multiple myeloma

    Even H. Rustad;Venkata D. Yellapantula;Dominik Glodzik;Kylee H. Maclachlan

  • Small nucleolar RNAs as new biomarkers in chronic lymphocytic leukemia

    Domenica Ronchetti;Laura Mosca;Giovanna Cutrona;Giacomo Tuana

  • miR-451a is underexpressed and targets AKT/mTOR pathway in papillary thyroid carcinoma

    Emanuela Minna;Paola Romeo;Matteo Dugo;Loris De Cecco

  • Clinical Monoclonal B Lymphocytosis versus Rai 0 Chronic Lymphocytic Leukemia: A Comparison of Cellular, Cytogenetic, Molecular, and Clinical Features

    Fortunato Morabito;Laura Mosca;Giovanna Cutrona;Luca Agnelli

Frequent Co-Authors

Antonino Neri
Antonino Neri University of Milan
Manlio Ferrarini
Manlio Ferrarini University of Genoa
Silvio Bicciato
Silvio Bicciato University of Modena and Reggio Emilia
Pierfrancesco Tassone
Pierfrancesco Tassone Magna Graecia University
Giorgio Inghirami
Giorgio Inghirami Cornell University
Pellegrino Musto
Pellegrino Musto University of Bari Aldo Moro
Francesco Bertoni
Francesco Bertoni Institute of Oncology Research
Francesco Di Raimondo
Francesco Di Raimondo University of Catania
Antonio Palumbo
Antonio Palumbo University of Turin
Valentina Bollati
Valentina Bollati University of Milan

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