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Marcelo J. Villar

Marcelo J. Villar

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Neuroscience
Argentina
2026

D-Index & Metrics

Neuroscience

D-Index
47
Citations
8271
World Ranking
6445
National Ranking
12

Research.com Recognitions

  • 2026 - Research.com Neuroscience in Argentina Leader Award
  • 2025 - Research.com Neuroscience in Argentina Leader Award

Overview

Marcelo J. Villar is affiliated with Austral University in Argentina and specializes in research across multiple domains within medicine and neuroscience. Their work involves significant contributions to understanding pain mechanisms, neuroinflammation, neurodegeneration, and the molecular basis of neurological and inflammatory responses.

The scientist's publication record includes research on the neuroprotective, antioxidant, and anti-inflammatory effects of compounds such as resveratrol, as well as studies on chemotherapy-induced neuropathic pain and sex-related differences in pain responses. Notable recent papers include:

  • Antioxidant, anti-inflammatory and neuroprotective actions of resveratrol after experimental nervous system insults. Special focus on the molecular mechanisms involved (2021, Neurochemistry International)
  • Resveratrol exerts anti-oxidant and anti-inflammatory actions and prevents oxaliplatin-induced mechanical and thermal allodynia (2020, Brain Research)
  • Changes in the expression of endocannabinoid system components in an experimental model of chemotherapy-induced peripheral neuropathic pain: Evaluation of sex-related differences (2022, Experimental Neurology)
  • Sex-related differences in oxaliplatin-induced changes in the expression of transient receptor potential channels and their contribution to cold hypersensitivity (2022, Neuroscience Letters)
  • Limitation of life-sustaining treatment in NICU: Physicians' beliefs and attitudes in the Buenos Aires region (2020, Early Human Development)

Frequent co-authors contributing to their research network include Pablo R. Brumovsky, María Florencia Coronel, Alejandro D. Montaner, Julia Rubione, and Candelaria Leiguarda. This collaborative environment reflects a diverse and interdisciplinary approach to scientific inquiry.

The researcher has published primarily in venues relevant to pain research, neuroimmunology, and neuroscience, including:

  • Journal of Pain
  • Journal of Neuroimmune Pharmacology
  • Neurochemistry International
  • Brain Research
  • Experimental Neurology

Their core fields of study encompass Medicine and Neuroscience, with a focus on subfields such as Physiology, Cellular and Molecular Neuroscience, Pediatrics, Perinatology and Child Health, Neurology, and Psychiatry and Mental Health.

The main topics addressed by their research coverage include:

  • Pain Mechanisms and Treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Cancer, Stress, Anesthesia, and Immune Response
  • Sirtuins and Resveratrol in Medicine
  • Neuroscience and Neuropharmacology Research
  • Neuropeptides and Animal Physiology
  • Ethics and Legal Issues in Pediatric Healthcare

Best Publications

  • Increase of galanin-like immunoreactivity in rat dorsal root ganglion cells after peripheral axotomy.

    T. Hökfelt;Z. Wiesenfeld-Hallin;M. Villar;T. Melander

  • Expression of c-Fos immunoreactivity in transmitter-characterized neurons after stress

    Sandra Ceccatelli;Marcelo J. Villar;Menek Goldstein;Tomas Hokfelt

  • Neuropeptide expression in rat dorsal root ganglion cells and spinal cord after peripheral nerve injury with special reference to galanin.

    M.J. Villar;R. Cortés;E. Theodorsson;Z. Wiesenfeld-Hallin

  • Nitric oxide synthase in the rat anterior pituitary gland and the role of nitric oxide in regulation of luteinizing hormone secretion.

    Sandra Ceccatelli;Anna-Lena Hulting;Xu Zhang;Lars Gustafsson

  • Peptides and transmitter enzymes in hypothalamic magnocellular neurons after administration of hyperosmotic stimuli: comparison between messenger RNA and peptide/protein levels

    B. Meister;R. Cortés;M. J. Villar;M. Schalling

  • Localization of chemical messengers in magnocellular neurons of the hypothalamic supraoptic and paraventricular nuclei: An immunohistochemical study using experimental manipulations

    B. Meister;M.J. Villar;S. Ceccatelli;T. Hökfelt

  • The effects of intrathecal galanin and C-fiber stimulation on the flexor reflex in the rat.

    Z. Wiesenfeld-Hallin;M.J. Villar;T. Ho¨kfelt

  • On the Role of Galanin, Substance P and Other Neuropeptides in Primary Sensory Neurons of the Rat: Studies on Spinal Reflex Excitability and Peripheral Axotomy.

    X.-J. Xu;Z. Wiesenfeld-Hallin;M. J. Villar;J. Fahrenkrug

  • Nitric oxide synthase increases in hypothalamic magnocellular neurons after salt loading in the rat. An immunohistochemical and in situ hybridization study

    Marcelo J. Villar;Sandra Ceccatelli;Marina Rönnqvist;Tomas Hökfelt

  • Further studies on galanin-, substance P-, and CGRP-like immunoreactivities in primary sensory neurons and spinal cord: effects of dorsal rhizotomies and sciatic nerve lesions.

    Marcelo J. Villar;Zsuzsanna Wiesenfeld-Hallin;Xiao-Jun Xu;Elvar Theodorsson

  • Distribution of D4 dopamine receptor in rat brain with sequence-specific antibodies

    María Cristina Defagot;Emilio L. Malchiodi;Marcelo J. Villar;Marta C. Antonelli

  • Expanded distribution of mRNA for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the rat brain after colchicine treatment

    S Ceccatelli;P Ernfors;M J Villar;H Persson

  • Expression of β-nerve growth factor receptor mRNA in Sertoli cells downregulated by testosterone.

    H Persson;C Ayer-Le Lievre;O Soder;MJ Villar

  • In vitro and in vivo differentiation of boundary cap neural crest stem cells into mature Schwann cells.

    Jorge B. Aquino;Jens Hjerling-Leffler;Martin Koltzenburg;Thomas Edlund

  • Dorsal raphe serotoninergic branching neurons projecting both to the lateral geniculate body and superior colliculus: A combined retrograde tracing–immunohistochemical study in the rat

    Marcelo J. Villar;Maria L. Vitale;Tomas Hökfelt;Albert A. J. Verhofstad

  • Intrathecal galanin potentiates the spinal analgesic effect of morphine: electrophysiological and behavioural studies.

    Wiesenfeld-Hallin Z;Xu Xj;Villar Mj;Hökfelt T

  • Neuropeptide tyrosine and pain

    Pablo Brumovsky;Pablo Brumovsky;Tiejun S. Shi;Marc Landry;Marcelo J. Villar

  • The effect of intrathecal galanin on the flexor reflex in rat: increased depression after sciatic nerve section.

    Z. Wiesenfeld-Hallin;X.-J. Xu;M.J. Villar;T. Hökfelt

  • Effects of central nervous system lesions on the expression of galanin: a comparative in situ hybridization and immunohistochemical study.

    Roser Cortes;Marcelo J. Villar;Albert Verhofstad;Tomas Hokfelt

  • Calcitonin gene-related peptide in the brain, spinal cord, and some peripheral systems.

    Tomas Hökfelt;Ulf Arvidsson;Sandra Ceccatelli;Roser Cortés

Frequent Co-Authors

Tomas Hökfelt
Tomas Hökfelt Karolinska Institute
Sandra Ceccatelli
Sandra Ceccatelli Karolinska Institute
Alejandro F. De Nicola
Alejandro F. De Nicola University of Buenos Aires
Zsuzsanna Wiesenfeld-Hallin
Zsuzsanna Wiesenfeld-Hallin Karolinska Institute
Florencia Labombarda
Florencia Labombarda University of Buenos Aires
Valerie M. K. Verge
Valerie M. K. Verge University of Saskatchewan
X.-J. Xu
X.-J. Xu Karolinska Institute
Tamas Bartfai
Tamas Bartfai Stockholm University
Ulf Arvidsson
Ulf Arvidsson Karolinska Institute
Håkan Persson
Håkan Persson Läkemedelsverket

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