What is he best known for?
The fields of study he is best known for:
José A. Esté focuses on Virology, Molecular biology, Virus, Cell biology and Syncytium.
His Virology study integrates concerns from other disciplines, such as Mutation and CXCR4 antagonist.
His work carried out in the field of Molecular biology brings together such families of science as CXCR4 Inhibitor, CCR1, T cell, Integrase and Signal transduction.
His Virus research incorporates themes from V3 loop and Glycoprotein.
The concepts of his Cell biology study are interwoven with issues in Cell, Lipid bilayer fusion, Apoptosis, Programmed cell death and Glycoprotein complex.
José A. Esté has included themes like Peripheral blood mononuclear cell and Cell fusion in his Syncytium study.
His most cited work include:
- AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor (687 citations)
- Inhibition of T-tropic HIV Strains by Selective Antagonization of the Chemokine Receptor CXCR4 (524 citations)
- HIV entry inhibitors. (243 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of investigation include Virology, Virus, Viral replication, Molecular biology and Stereochemistry.
His Virology study combines topics in areas such as Cell culture, Reverse transcriptase and Immunology.
José A. Esté interconnects V3 loop and In vitro, Mechanism of action in the investigation of issues within Virus.
His research investigates the connection between Viral replication and topics such as SAMHD1 that intersect with problems in Cell cycle, Cyclin-dependent kinase 6, Cyclin-dependent kinase and Kinase.
The study incorporates disciplines such as Integrase and T cell in addition to Molecular biology.
His research in Stereochemistry intersects with topics in Structure–activity relationship, Chemical synthesis, Mutant and Enzyme.
He most often published in these fields:
- Virology (45.62%)
- Virus (26.27%)
- Viral replication (17.51%)
What were the highlights of his more recent work (between 2011-2020)?
- Virology (45.62%)
- Viral replication (17.51%)
- SAMHD1 (6.91%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Virology, Viral replication, SAMHD1, Stereochemistry and Reverse transcriptase.
His Virology research incorporates elements of Immunology and Immune system.
His Viral replication research is under the purview of Virus.
He combines subjects such as Amino acid, Cell and Antigen with his study of Virus.
His SAMHD1 research is multidisciplinary, incorporating elements of Cyclin-dependent kinase, Cell cycle, Cyclin-dependent kinase 6, Molecular biology and Kinase.
His Reverse transcriptase research is multidisciplinary, relying on both Enzyme assay, Enzyme, In vitro, Docking and Mutant.
Between 2011 and 2020, his most popular works were:
- Cell Cycle Control and HIV-1 Susceptibility Are Linked by CDK6-Dependent CDK2 Phosphorylation of SAMHD1 in Myeloid and Lymphoid Cells (103 citations)
- SAMHD1: At the Crossroads of Cell Proliferation, Immune Responses, and Virus Restriction (58 citations)
- Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents. (57 citations)
In his most recent research, the most cited papers focused on:
José A. Esté mostly deals with SAMHD1, Molecular biology, Viral replication, Virology and Reverse transcriptase.
His research on SAMHD1 also deals with topics like
- Cyclin-dependent kinase 6 that intertwine with fields like Kinase,
- Cell cycle that intertwine with fields like Intracellular,
- Cyclin-dependent kinase which is related to area like Cell biology.
His studies in Molecular biology integrate themes in fields like Cell culture, In vitro, Zinc finger nuclease, CD28 and Phosphorylation.
His Viral replication study is concerned with the larger field of Virus.
The various areas that he examines in his Virology study include Transcription and Small molecule.
His study in Reverse transcriptase is interdisciplinary in nature, drawing from both Structure–activity relationship, Stereochemistry, Zidovudine and Stereoisomerism.
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