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Biology and Biochemistry

D-Index
52
Citations
36953
World Ranking
16403
National Ranking
365

Overview

Jordi Barretina is a researcher affiliated with the Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol in Spain. Their work primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on various specialized subfields including Cognitive Neuroscience, Molecular Biology, Cancer Research, Genetics, and Radiology, Nuclear Medicine and Imaging.

Their research explores several main topics, among which are:

  • Cancer Genomics and Diagnostics
  • Functional Brain Connectivity Studies
  • Neural dynamics and brain function
  • Genomic variations and chromosomal abnormalities
  • Advanced MRI Techniques and Applications
  • Diet and metabolism studies
  • Single-cell and spatial transcriptomics

Jordi Barretina has published frequently in venues such as bioRxiv (Cold Spring Harbor Laboratory), Cerebral Cortex, Cell Reports, Cancer Research, and UNC Libraries.

Recent publications include:

  • Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes, 2021, Nature Communications
  • Whole-Brain Dynamics in Aging: Disruptions in Functional Connectivity and the Role of the Rich Club, 2020, Cerebral Cortex
  • Obesity-associated deficits in inhibitory control are phenocopied to mice through gut microbiota changes in one-carbon and aromatic amino acids metabolic pathways, 2021, Gut
  • Plasma acylcarnitines and gut-derived aromatic amino acids as sex-specific hub metabolites of the human aging metabolome, 2023, Aging Cell
  • Preclinical evaluation of a COVID-19 vaccine candidate based on a recombinant RBD fusion heterodimer of SARS-CoV-2, 2023, iScience

Their frequent collaborators include Rafel Ramos, Carles Biarnés, Josep Garre-Olmo, José Manuel Fernández-Real, and Reinald Pamplona.

Best Publications

  • The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

    Jordi Barretina;Giordano Caponigro;Nicolas Stransky;Kavitha Venkatesan

  • The landscape of somatic copy-number alteration across human cancers

    Rameen Beroukhim;Craig H. Mermel;Craig H. Mermel;Dale Porter;Guo Wei

  • Next-generation characterization of the Cancer Cell Line Encyclopedia

    Mahmoud Ghandi;Franklin W. Huang;Franklin W. Huang;Franklin W. Huang;Judit Jané-Valbuena;Judit Jané-Valbuena;Gregory V. Kryukov

  • COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

    Cory M Johannessen;Jesse S. Boehm;So Young Kim;Sapana R. Thomas;Sapana R. Thomas

  • Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

    Richard Possemato;Kevin M. Marks;Yoav D. Shaul;Michael E. Pacold

  • Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma

    Rameen Beroukhim;Gad Getz;Leia Nghiemphu;Jordi Barretina

  • High-throughput oncogene mutation profiling in human cancer

    Roman K. Thomas;Alissa C. Baker;Ralph M. DeBiasi;Ralph M. DeBiasi;Wendy Winckler;Wendy Winckler

  • Melanoma genome sequencing reveals frequent PREX2 mutations

    Michael F. Berger;Michael F. Berger;Eran Hodis;Timothy P. Heffernan;Timothy P. Heffernan;Yonathan Lissanu Deribe

  • Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy.

    Jordi Barretina;Barry S Taylor;Barry S Taylor;Shantanu Banerji;Shantanu Banerji;Alexis H Ramos;Alexis H Ramos

  • CDK8 is a colorectal cancer oncogene that regulates β-catenin activity

    Ron Firestein;Adam Bass;So Young Kim;Ian Frederick Dunn

  • An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules

    Amrita Basu;Nicole E. Bodycombe;Jaime H. Cheah;Edmund V. Price

  • The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer.

    Mark M. Pomerantz;Nasim Ahmadiyeh;Nasim Ahmadiyeh;Li Jia;Paula Herman

  • Focal Gains of VEGFA and Molecular Classification of Hepatocellular Carcinoma

    Derek Y. Chiang;Augusto Villanueva;Yujin Hoshida;Yujin Hoshida;Judit Peix

  • Pharmacogenomic agreement between two cancer cell line data sets

    Nicolas Stransky;Mahmoud Ghandi

  • Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling.

    Christina Gewinner;Zhigang C. Wang;Andrea Richardson;Julie Teruya-Feldstein

  • Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer

    Hiu Wing Cheung;Glenn S. Cowley;Barbara A. Weir;Jesse S. Boehm

  • The landscape of cancer cell line metabolism

    Haoxin Li;Haoxin Li;Shaoyang Ning;Mahmoud Ghandi;Gregory V. Kryukov

  • Advances in sarcoma genomics and new therapeutic targets

    Barry S. Taylor;Jordi Barretina;Jordi Barretina;Robert G. Maki;Cristina R. Antonescu

  • Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A - TCF7L2 fusion

    Adam J. Bass;Adam J. Bass;Michael S. Lawrence;Lear E. Brace;Alex H. Ramos;Alex H. Ramos

  • Integrative analysis of the melanoma transcriptome.

    Michael F. Berger;Joshua Z. Levin;Krishna Vijayendran;Krishna Vijayendran;Andrey Sivachenko

Frequent Co-Authors

Levi A. Garraway
Levi A. Garraway Roche (United States)
Matthew Meyerson
Matthew Meyerson Harvard University
William R. Sellers
William R. Sellers Harvard University
Todd R. Golub
Todd R. Golub Harvard University
Gad Getz
Gad Getz Broad Institute
Eric S. Lander
Eric S. Lander Broad Institute
Barbara A. Weir
Barbara A. Weir Janssen (United States)
José A. Esté
José A. Esté Autonomous University of Barcelona
Julià Blanco
Julià Blanco IrsiCaixa
Rameen Beroukhim
Rameen Beroukhim Harvard University

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