Mohammed Jemal

Overview

Best Publications

• High-throughput quantitative bioanalysis by LC/MS/MS.

  Mohammed Jemal

  519
  Citations

• Phospholipids in liquid chromatography/mass spectrometry bioanalysis: comparison of three tandem mass spectrometric techniques for monitoring plasma phospholipids, the effect of mobile phase composition on phospholipids elution and the association of phospholipids with matrix effects

  Yuan-Qing Xia;Mohammed Jemal

  296
  Citations

• Liquid chromatography/tandem mass spectrometry methods for quantitation of mevalonic acid in human plasma and urine: method validation, demonstration of using a surrogate analyte, and demonstration of unacceptable matrix effect in spite of use of a stable isotope analog internal standard.

  Mohammed Jemal;Alan Schuster;Daisy B. Whigan

  280
  Citations

• LC-MS Development strategies for quantitative bioanalysis.

  Mohammed Jemal;Yuan-Qing Xia

  262
  Citations

• Systematic LC-MS/MS bioanalytical method development that incorporates plasma phospholipids risk avoidance, usage of incurred sample and well thought-out chromatography

  Mohammed Jemal;Zheng Ouyang;Yuan-Qing Xia

  256
  Citations

• Quantitation of the acid and lactone forms of atorvastatin and its biotransformation products in human serum by high-performance liquid chromatography with electrospray tandem mass spectrometry.

  Mohammed Jemal;Zheng Ouyang;Bang-Chi Chen;Deborah Teitz

  202
  Citations

• Bioavailability enhancement of a poorly water-soluble drug by solid dispersion in polyethylene glycol-polysorbate 80 mixture.

  Hemant N Joshi;Ravindra W Tejwani;Martha Davidovich;Vaishali P Sahasrabudhe

  194
  Citations

• It is time for a paradigm shift in drug discovery bioanalysis: from SRM to HRMS.

  Ragu Ramanathan;Mohammed Jemal;Suma Ramagiri;Yuan-Qing Xia

  193
  Citations

• The need for adequate chromatographic separation in the quantitative determination of drugs in biological samples by high performance liquid chromatography with tandem mass spectrometry

  Mohammed Jemal;Yuan-Qing Xia

  181
  Citations

• Direct-injection LC–MS–MS method for high-throughput simultaneous quantitation of simvastatin and simvastatin acid in human plasma

  Mohammed Jemal;Zheng Ouyang;Mark L. Powell

  154
  Citations

• The use of high-flow high performance liquid chromatography coupled with positive and negative ion electrospray tandem mass spectrometry for quantitative bioanalysis via direct injection of the plasma/serum samples.

  M. Jemal;Yuan-Qing;Daisy B. Whigan

  148
  Citations

• 2011 White paper on recent issues in bioanalysis and regulatory findings from audits and inspections.

  Fabio Garofolo;Mario L Rocci;Isabelle Dumont;Suzanne Martinez

  132
  Citations

• A universal surrogate peptide to enable LC-MS/MS bioanalysis of a diversity of human monoclonal antibody and human Fc-fusion protein drug candidates in pre-clinical animal studies.

  Michael T. Furlong;Zheng Ouyang;Steven Wu;James Tamura

  129
  Citations

• Pellet digestion: a simple and efficient sample preparation technique for LC-MS/MS quantification of large therapeutic proteins in plasma.

  Zheng Ouyang;Michael T Furlong;Steven Wu;Bogdan Sleczka

  110
  Citations

• Targeted quantitative bioanalysis in plasma using liquid chromatography/high-resolution accurate mass spectrometry: an evaluation of global selectivity as a function of mass resolving power and extraction window, with comparison of centroid and profile modes.

  Yuan-Qing Xia;Jim Lau;Timothy Olah;Mohammed Jemal

  109
  Citations

• LC-FAIMS-MS/MS for quantification of a peptide in plasma and evaluation of FAIMS global selectivity from plasma components.

  Yuan-Qing Xia;Steven T Wu;Mohammed Jemal

  104
  Citations

• A strategy for liquid chromatography/tandem mass spectrometry based quantitation of pegylated protein drugs in plasma using plasma protein precipitation with water-miscible organic solvents and subsequent trypsin digestion to generate surrogate peptides for detection.

  Steven T. Wu;Zheng Ouyang;Timothy V. Olah;Mohammed Jemal

  103
  Citations

• Full-scan high resolution accurate mass spectrometry (HRMS) in regulated bioanalysis: LC-HRMS for the quantitation of prednisone and prednisolone in human plasma.

  Eliza N. Fung;Yuan-qing Xia;Anne-Francoise Aubry;Jianing Zeng

  97
  Citations

• Comparison of plasma sample purification by manual liquid–liquid extraction, automated 96-well liquid–liquid extraction and automated 96-well solid-phase extraction for analysis by high-performance liquid chromatography with tandem mass spectrometry

  Mohammed Jemal;Deborah Teitz;Zheng Ouyang;Sanaullah Khan

  93
  Citations

• Quantitative determination of pravastatin and its biotransformation products in human serum by turbo ion spray LC/MS/MS.

  Daniel Mulvana;Mohammed Jemal;Sabine Coates Pulver

  88
  Citations

• A strategy for metabolite identification using triple‐quadrupole mass spectrometry with enhanced resolution and accurate mass capability

  Mohammed Jemal;Zheng Ouyang;Weiping Zhao;Mingshe Zhu

  85
  Citations