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Immunology

D-Index
68
Citations
15773
World Ranking
2598
National Ranking
1240

Overview

Dorothee Herlyn is affiliated with The Wistar Institute in the United States and has contributed research primarily in the fields of Biochemistry, Genetics, and Molecular Biology. Their work spans several subfields including Cell Biology, Molecular Biology, and Oncology.

The scientist's research topics focus on melanin and skin pigmentation, RNA regulation and disease, and cutaneous melanoma detection and management. These areas represent the core themes explored across their published work.

Among recent publications, two noteworthy papers include:

  • In Memoriam: Rajasekharan (Shyam) Somasundaram (1956-2021), published in 2021 in Pigment Cell & Melanoma Research
  • The state of melanoma: challenges and opportunities, published in 2020 in UNC Libraries

Dorothee Herlyn has collaborated frequently with several researchers in related disciplines. Frequent coauthors include:

  • Meenhard Herlyn
  • Glenn Merlino
  • David E. Fisher
  • Boris C. Bastian
  • Keith T. Flaherty

The primary venues for publication reflect these collaborations and subject focus, consisting of:

  • Pigment Cell & Melanoma Research
  • UNC Libraries

Best Publications

  • Colorectal carcinoma antigens detected by hybridoma antibodies

    Hilary Koprowski;Zenon Steplewski;Kenneth Mitchell;Meenhard Herlyn

  • Circulating tumor cells in patients with breast cancer dormancy

    Songdong Meng;Debasish Tripathy;Eugene P. Frenkel;Sanjay Shete

  • Colorectal carcinoma-specific antigen: detection by means of monoclonal antibodies

    Meenhard Herlyn;Zenon Steplewski;Dorothee Herlyn;Hilary Koprowski

  • HER-2 gene amplification can be acquired as breast cancer progresses.

    Songdong Meng;Debasish Tripathy;Sanjay Shete;Raheela Ashfaq

  • Study of antibodies against human melanoma produced by somatic cell hybrids.

    Hilary Koprowski;Zenon Steplewski;Dorothee Herlyn;Meenhard Herlyn

  • PHASE-I CLINICAL TRIAL OF MONOCLONAL ANTIBODY IN TREATMENT OF GASTROINTESTINAL TUMOURS

    HenryF. Sears;Jeffrey Mattis;Dorothee Herlyn;Pekka Häyry

  • IgG2a monoclonal antibodies inhibit human tumor growth through interaction with effector cells

    Dorothee Herlyn;Hilary Koprowski

  • Characteristics of Cultured Human Melanocytes Isolated from Different Stages of Tumor Progression

    M Herlyn;J Thurin;G Balaban;J L Bennicelli

  • Human anti-idiotype antibodies in cancer patients: Is the modulation of the immune response beneficial for the patient?

    Hilary Koprowski;Dorothee Herlyn;Michael Lubeck;Elaine Defreitas

  • Inhibition of Growth of Colorectal Carcinoma in Nude Mice by Monoclonal Antibody

    Dorothee M. Herlyn;Zenon Steplewski;Meenhard F. Herlyn;Hilary Koprowski

  • Inhibition of Cytolytic T Lymphocyte Proliferation by Autologous CD4+/CD25+ Regulatory T Cells in a Colorectal Carcinoma Patient Is Mediated by Transforming Growth Factor-β

    Rajasekharan Somasundaram;Lutz Jacob;Rolf Swoboda;Laura Caputo

  • Anti-idiotype immunization of cancer patients: modulation of the immune response.

    D Herlyn;M Wettendorff;E Schmoll;D Iliopoulos

  • Effects of monoclonal antibody immunotherapy on patients with gastrointestinal adenocarcinoma.

    H F Sears;D Herlyn;Z Steplewski;H Koprowski

  • Tumor Growth Modulation by a Monoclonal Antibody to the Epidermal Growth Factor Receptor: Immunologically Mediated and Effector Cell-independent Effects

    Ulrich Rodeck;Meenhard Herlyn;Dorothee Herlyn;Carla Molthoff

  • uPAR and HER-2 gene status in individual breast cancer cells from blood and tissues.

    Songdong Meng;Debasish Tripathy;Sanjay Shete;Raheela Ashfaq

  • Monoclonal antibodies in cell-mediated cytotoxicity against human melanoma and colorectal carcinoma.

    Dorothee Herlyn;Meenhard Herlyn;Zenon Steplewski;Hilary Koprowski

  • Phase II clinical trial of a murine monoclonal antibody cytotoxic for gastrointestinal adenocarcinoma.

    Henry F. Sears;Dorothee Herlyn;Zenon Steplewski;Hilary Koprowski

  • Primary Melanoma Cells of the Vertical Growth Phase: Similarities to Metastatic Cells

    Herlyn M;Balaban G;Bennicelli J;Guerry D th

  • Anti-idiotypic antibodies bear the internal image of a human tumor antigen

    Dorothee Herlyn;Alonzo H. Ross;Hilary Koprowski

  • Antibody-dependent cytotoxicity mediated by natural killer cells is enhanced by castanospermine-induced alterations of IgG glycosylation

    Ronald Jay Rothman;Bice Perussia;Dorothee Herlyn;Leonard Warren

  • Characteristics of cultured human melanocytes from different stages of tumor progression

    Ulrich Rodeck;Meenhard Herlyn

Frequent Co-Authors

Meenhard Herlyn
Meenhard Herlyn The Wistar Institute
Hilary Koprowski
Hilary Koprowski Thomas Jefferson University
David E. Elder
David E. Elder Hospital of the University of Pennsylvania
Francesco M. Marincola
Francesco M. Marincola National Institutes of Health
Alonzo H. Ross
Alonzo H. Ross University of Massachusetts Chan Medical School
Dimitrios Iliopoulos
Dimitrios Iliopoulos University of California, Los Angeles
David W. Speicher
David W. Speicher The Wistar Institute
Ulrich Rodeck
Ulrich Rodeck Thomas Jefferson University
Abass Alavi
Abass Alavi University of Pennsylvania
Lynn M. Schuchter
Lynn M. Schuchter University of Pennsylvania

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