D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 85 Citations 26,079 250 World Ranking 524 National Ranking 311
Medicine D-index 88 Citations 28,013 277 World Ranking 6494 National Ranking 3587

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Antibody

His main research concerns Antigen, Molecular biology, Monoclonal antibody, Antibody and Immunology. His Antigen study combines topics in areas such as Immune system, Immunotherapy, Pathology, Melanoma and Ganglioside. His Molecular biology research is multidisciplinary, incorporating perspectives in Cytotoxic T cell, Cell, Melanotransferrin and Peptide sequence.

Karl Erik Hellström has researched Monoclonal antibody in several fields, including In vitro, Cytotoxicity, Biochemistry and Ricin. His In vitro research includes elements of Lymph node and Transplantation. His Immunology research integrates issues from Neuroblastoma cell and Neoplasm Transplantation.

His most cited work include:

  • Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4 (1026 citations)
  • Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors (835 citations)
  • Demonstration of resistance against methylcholanthrene-induced sarcomas in the primary autochthonous host. (654 citations)

What are the main themes of his work throughout his whole career to date?

Karl Erik Hellström mostly deals with Antigen, Molecular biology, Immunology, Antibody and Monoclonal antibody. The various areas that Karl Erik Hellström examines in his Antigen study include In vitro, Neoplasm, Pathology, Melanoma and Immunotherapy. As a member of one scientific family, Karl Erik Hellström mostly works in the field of Molecular biology, focusing on Cytotoxic T cell and, on occasion, Virology.

His Antibody study frequently draws connections between related disciplines such as Internal medicine. His work on Pan-T antigens is typically connected to Conjugate as part of general Monoclonal antibody study, connecting several disciplines of science. His studies in Immune system integrate themes in fields like Cancer research and Transfection.

He most often published in these fields:

  • Antigen (63.25%)
  • Molecular biology (46.99%)
  • Immunology (45.18%)

What were the highlights of his more recent work (between 1996-2020)?

  • Immunology (45.18%)
  • Immune system (25.00%)
  • Antibody (39.16%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Immunology, Immune system, Antibody, Cancer research and Monoclonal antibody. In his research on the topic of Immunology, Clone is strongly related with Melanoma. His Antibody research includes themes of Cancer, Clinical efficacy, Tumor cells and Pathology.

His Monoclonal antibody research includes elements of Molecular biology, In vitro, Biochemistry and Doxorubicin. He has included themes like Tumor necrosis factor alpha, Transplantation and Antigen in his Immunotherapy study. Antigen and Carcinoma are frequently intertwined in his study.

Between 1996 and 2020, his most popular works were:

  • Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors (835 citations)
  • AMPLIFICATION OF TUMOR IMMUNITY BY GENE TRANSFER OF THE CO-STIMULATORY 4-1BB LIGAND : SYNERGY WITH THE CD28 CO-STIMULATORY PATHWAY (216 citations)
  • Cutting edge: CD83 regulates the development of cellular immunity. (129 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Antibody

Karl Erik Hellström spends much of his time researching Monoclonal antibody, Cytotoxic T cell, Doxorubicin, Immunology and Pathology. His Monoclonal antibody study combines topics in areas such as CD8 and Antigen. His CD8 study which covers Immunotherapy that intersects with Molecular biology.

Within one scientific family, he focuses on topics pertaining to T cell under Cytotoxic T cell, and may sometimes address concerns connected to Interleukin 12 and Cell biology. As part of the same scientific family, Karl Erik Hellström usually focuses on Immunology, concentrating on Cancer research and intersecting with Antigen-presenting cell. His Pathology study incorporates themes from Cancer, Urine, Creatinine, Antibody and Receiver operating characteristic.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

Lieping Chen;Stephanie Ashe;William A. Brady;Ingegerd Hellström.
Cell (1992)

1370 Citations

Demonstration of resistance against methylcholanthrene-induced sarcomas in the primary autochthonous host.

George Klein;Hans Olof Sjögren;Eva Klein;Karl Erik Hellström.
Cancer Research (1960)

1022 Citations

Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors

Ignacio Melero;Walter W. Shuford;Stephanie Ashe Newby;Alejandro Aruffo.
Nature Medicine (1997)

980 Citations

Suggestive evidence that the 'blocking antibodies' of tumor-bearing individuals may be antigen-antibody complexes.

H. O. Sjögren;I. Hellström;S. C. Bansal;K. E. Hellström.
Proceedings of the National Academy of Sciences of the United States of America (1971)

928 Citations

Tumor immunogenicity determines the effect of B7 costimulation on T cell-mediated tumor immunity

Lieping Chen;Patrick McGowan;Stephanie Ashe;Janet Johnston.
Journal of Experimental Medicine (1994)

719 Citations

Cellular immunity against tumor antigens.

Karl Erik Hellström;Ingegerd Hellström.
Advances in Cancer Research (1969)

645 Citations

Blocking of cell-mediated tumor immunity by sera from patients with growing neoplasms.

Ingegerd Hellström;Hans Olov Sjögren;Glenn Warner;Karl Erik Hellström.
International Journal of Cancer (1971)

565 Citations

Chimeric mouse-human IgG1 antibody that can mediate lysis of cancer cells.

A Y Liu;R R Robinson;K E Hellström;E D Murray.
Proceedings of the National Academy of Sciences of the United States of America (1987)

554 Citations

Cellular and Humoral immunity to Different Types of Human Neoplasms

I Hellstrom;K E Hellstrom;G E Pierce;J P S Yang.
Nature (1968)

496 Citations

Costimulation of T cells for tumor immunity

Lieping Chen;Peter S. Linsley;Karl Erik Hellström.
Immunology Today (1993)

482 Citations

Best Scientists Citing Karl Erik Hellström

Lieping Chen

Lieping Chen

Yale University

Publications: 90

Robert W. Baldwin

Robert W. Baldwin

University of Nottingham

Publications: 71

Byoung S. Kwon

Byoung S. Kwon

Tulane University

Publications: 71

Soldano Ferrone

Soldano Ferrone

Harvard University

Publications: 71

Ignacio Melero

Ignacio Melero

University of Navarra

Publications: 70

Jeffrey Schlom

Jeffrey Schlom

National Institutes of Health

Publications: 51

David M. Goldenberg

David M. Goldenberg

Pennsylvania State University

Publications: 47

Donald L. Morton

Donald L. Morton

Saint John's Health Center

Publications: 41

Koji Tamada

Koji Tamada

Yamaguchi University

Publications: 41

Peter D. Senter

Peter D. Senter

Seattle Genetics (United States)

Publications: 40

Ingegerd Hellström

Ingegerd Hellström

University of Washington

Publications: 33

Hideo Yagita

Hideo Yagita

Juntendo University

Publications: 31

Mark J. Smyth

Mark J. Smyth

QIMR Berghofer Medical Research Institute

Publications: 30

Steven A. Rosenberg

Steven A. Rosenberg

National Institutes of Health

Publications: 30

Thierry Boon

Thierry Boon

Ludwig Cancer Research

Publications: 29

Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking d-index is inferred from publications deemed to belong to the considered discipline.

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