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Immunology

D-Index
97
Citations
33455
World Ranking
826
National Ranking
466

Medicine

D-Index
98
Citations
33619
World Ranking
8950
National Ranking
4605

Overview

Karl Erik Hellström is affiliated with the University of Washington in the United States. Their research primarily focuses on the fields of medicine and immunology and microbiology, with published work spanning key subfields such as oncology, immunology, and radiology, nuclear medicine, and imaging.

Their work reflects a concentration on several major topics within biomedical research, including immunotherapy and immune responses, cancer immunotherapy and biomarkers, monoclonal and polyclonal antibodies research, and CAR-T cell therapy research.

Hellström has contributed scholarly articles to peer-reviewed journals, including publication in the Journal of Immunotherapy. A notable recent paper published in 2021 is titled "Antibodies to EGF Receptor Family Members Can Upregulate Tumor Immunity," appearing in the Journal of Immunotherapy.

The scientist collaborates frequently with a group of coauthors, including Min Dai, Ingegerd Hellström, Yuen Yee Yip, and George J. Todaro. Among these, Min Dai and Ingegerd Hellström have been involved in multiple joint publications, indicating sustained research partnerships.

  • Antibodies to EGF Receptor Family Members Can Upregulate Tumor Immunity, 2021, Journal of Immunotherapy

  • Min Dai
  • Ingegerd Hellström
  • Yuen Yee Yip
  • George J. Todaro

  • Journal of Immunotherapy

  • Medicine
  • Immunology and Microbiology

  • Oncology
  • Immunology
  • Radiology, Nuclear Medicine and Imaging

  • Immunotherapy and Immune Responses
  • Cancer Immunotherapy and Biomarkers
  • Monoclonal and Polyclonal Antibodies Research
  • CAR-T cell therapy research

Best Publications

  • Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

    Lieping Chen;Stephanie Ashe;William A. Brady;Ingegerd Hellström

  • Demonstration of resistance against methylcholanthrene-induced sarcomas in the primary autochthonous host.

    George Klein;Hans Olof Sjögren;Eva Klein;Karl Erik Hellström

  • Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors

    Ignacio Melero;Walter W. Shuford;Stephanie Ashe Newby;Alejandro Aruffo

  • Suggestive evidence that the "blocking antibodies" of tumor-bearing individuals may be antigen--antibody complexes

    H. O. Sjögren;I. Hellström;S. C. Bansal;K. E. Hellström

  • Lymphocyte-Mediated Cytotoxicity And Blocking Serum Activity To Tumor Antigens

    Karl Erik Hellström;Ingegerd Hellström

  • Tumor immunogenicity determines the effect of B7 costimulation on T cell-mediated tumor immunity

    Lieping Chen;Patrick McGowan;Stephanie Ashe;Janet Johnston

  • Cellular immunity against tumor antigens.

    Karl Erik Hellström;Ingegerd Hellström

  • Blocking of cell-mediated tumor immunity by sera from patients with growing neoplasms.

    Ingegerd Hellström;Hans Olov Sjögren;Glenn Warner;Karl Erik Hellström

  • Chimeric mouse-human IgG1 antibody that can mediate lysis of cancer cells.

    A Y Liu;R R Robinson;K E Hellström;E D Murray

  • Cellular and humoral immunity to different types of human neoplasms

    I Hellstrom;K E Hellstrom;G E Pierce;J P S Yang

  • Costimulation of T cells for tumor immunity

    Lieping Chen;Peter S. Linsley;Karl Erik Hellström

  • SOLUBLE MEMBER(S) OF THE MESOTHELIN/MEGAKARYOCYTE POTENTIATING FACTOR FAMILY ARE DETECTABLE IN SERA FROM PATIENTS WITH OVARIAN CARCINOMA

    Nathalie Scholler;Ning Fu;Yi Yang;Zhengmao Ye

  • Studies on cellular immunity and its serum mediated inhibition in Moloney-virus-induced mouse sarcomas.

    Ingegerd Hellström;Karl Erik Hellström

  • Imaging of Melanoma with I-131-Labeled Monoclonal Antibodies

    Steven M. Larson;Joseph P. Brown;Peter W. Wright;Jorge A. Carrasquillo

  • Human melanoma-associated antigen p97 is structurally and functionally related to transferrin

    Joseph P. Brown;Rodney M. Hewick;Ingegerd Hellström;Karl Erik Hellström

  • Demonstration of cell-bound and humoral immunity against neuroblastoma cells.

    Ingegerd E. Hellstrom;Karl Erik Hellstrom;George E. Pierce;Alexander H. Bill

  • Structural characterization of human melanoma-associated antigen p97 with monoclonal antibodies.

    J P Brown;K Nishiyama;I Hellström;K E Hellström

  • Human papillomavirus type 16 nucleoprotein E7 is a tumor rejection antigen.

    Lieping Chen;Elaine Kinney Thomas;Shiu Lok Hu;Ingegerd Hellström

  • Localization of 131I-labeled p97-specific Fab fragments in human melanoma as a basis for radiotherapy.

    S M Larson;J A Carrasquillo;K A Krohn;J P Brown

  • AMPLIFICATION OF TUMOR IMMUNITY BY GENE TRANSFER OF THE CO-STIMULATORY 4-1BB LIGAND : SYNERGY WITH THE CD28 CO-STIMULATORY PATHWAY

    Ignacio Melero;Nathan Bach;Karl Erik Hellström;Alejandro Aruffo

  • Highly tumor-reactive, internalizing, mouse monoclonal antibodies to Le(y)-related cell surface antigens.

    I Hellström;H J Garrigues;U Garrigues;K E Hellström

Frequent Co-Authors

Ingegerd Hellström
Ingegerd Hellström University of Washington
Lieping Chen
Lieping Chen Yale University
Irwin D. Bernstein
Irwin D. Bernstein Fred Hutchinson Cancer Research Center
Peter D. Senter
Peter D. Senter Seattle Genetics (United States)
Alejandro Aruffo
Alejandro Aruffo Syngenta (United States)
Gerald T. Nepom
Gerald T. Nepom Virginia Mason Medical Center
Kenneth A. Krohn
Kenneth A. Krohn Oregon Health & Science University
Elizabeth M. Swisher
Elizabeth M. Swisher University of Washington
Jeffrey A. Ledbetter
Jeffrey A. Ledbetter University of Washington
Jürgen Bajorath
Jürgen Bajorath University of Bonn

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