Nicolas Sergeant

Overview

Best Publications

• The biochemical pathway of neurofibrillary degeneration in aging and Alzheimer’s disease

  A. Delacourte;J.P. David;N. Sergeant;L. Buée

  1066
  Citations

• Massive CA1/2 Neuronal Loss with Intraneuronal and N-Terminal Truncated Aβ42 Accumulation in a Novel Alzheimer Transgenic Model

  Caty Casas;Nicolas Sergeant;Jean-Michel Itier;Véronique Blanchard

  534
  Citations

• Nuclear Tau, a Key Player in Neuronal DNA Protection

  Audrey Sultan;Fabrice Nesslany;Marie Violet;Séverine Bégard

  447
  Citations

• Neurofibrillary degeneration in progressive supranuclear palsy and corticobasal degeneration: tau pathologies with exclusively "exon 10" isoforms.

  N Sergeant;A Wattez;A Delacourte

  394
  Citations

• Tau protein as a differential biomarker of tauopathies.

  Nicolas Sergeant;André Delacourte;Luc Buée

  369
  Citations

• Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegeneration

  Sébastien S. Hébert;Sébastien S. Hébert;Aikaterini S. Papadopoulou;Pascal Smith;Marie-Christine Galas;Marie-Christine Galas

  367
  Citations

• Biochemistry of Tau in Alzheimer’s disease and related neurological disorders

  Nicolas Sergeant;Alexis Bretteville;Malika Hamdane;Marie-Laure Caillet-Boudin

  350
  Citations

• Truncated beta-amyloid peptide species in pre-clinical Alzheimer's disease as new targets for the vaccination approach.

  Nicolas Sergeant;Stepanie Bombois;Antoine Ghestem;Hervé Drobecq

  344
  Citations

• Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy

  Charlotte Fugier;Arnaud F Klein;Caroline Hammer;Stéphane Vassilopoulos

  341
  Citations

• Dysregulation of human brain microtubule-associated tau mRNA maturation in myotonic dystrophy type 1

  Nicolas Sergeant;Bernard Sablonnière;Suzanna Schraen-Maschke;Antoine Ghestem

  323
  Citations

• Vulnerable neuronal subsets in Alzheimer's and Pick's disease are distinguished by their τ isoform distribution and phosphorylation

  A. Delacourte;N. Sergeant;A. Wattez;D. Gauvreau

  322
  Citations

• Tau phosphorylation and sevoflurane anesthesia: an association to postoperative cognitive impairment.

  Le Freche H;Brouillette J;Fernandez-Gomez Fj;Patin P

  281
  Citations

• Specific pathological Tau protein variants characterize Pick's disease.

  André Delacourte;Yves Robitaille;Nicolas Sergeant;Luc Buée

  275
  Citations

• Mice transgenic for the human myotonic dystrophy region with expanded CTG repeats display muscular and brain abnormalities

  Hervé Seznec;Onnik Agbulut;Nicolas Sergeant;Cédric Savouret

  265
  Citations

• miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo

  Pascal Y. Smith;Julia Hernandez-Rapp;Francis Jolivette;Cynthia Lecours

  246
  Citations

• Targeting phospho-Ser422 by active Tau Immunotherapy in the THYTau22 mouse model: a suitable therapeutic approach

  Laetitia Troquier;Raphaelle Caillierez;Sylvie Burnouf;Francisco J Fernandez-Gomez

  233
  Citations

• Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology.

  Karim Belarbi;Sylvie Burnouf;Francisco-Jose Fernandez-Gomez;Cyril Laurent

  215
  Citations

• Guadeloupean parkinsonism: a cluster of progressive supranuclear palsy‐like tauopathy

  Dominique Caparros‐Lefebvre;Nicolas Sergeant;Andrew Lees;Agnes Camuzat

  210
  Citations

• Alkalizing drugs induce accumulation of amyloid precursor protein by-products in luminal vesicles of multivesicular bodies.

  Valérie Vingtdeux;Malika Hamdane;Anne Loyens;Patrick Gelé

  208
  Citations

• Regulation of human MAPT gene expression.

  Marie-Laure Caillet-Boudin;Luc Buée;Nicolas Sergeant;Bruno Lefebvre

  206
  Citations