Toshiyuki Hamaoka

Overview

Best Publications

• Identification of a T cell-derived b cell growth factor distinct from interleukin 2.

  Maureen Howard;John Farrar;Mary Hilfiker;Barbara Johnson

  1411
  Citations

• Monoclonal antibodies to Pgp-1/CD44 block lympho-hemopoiesis in long-term bone marrow cultures.

  Kensuke Miyake;Kay L. Medina;Shin Ichi Hayashi;Shiro Ono

  798
  Citations

• New procedures for preparation and isolation of conjugates of proteins and a synthetic copolymer of D-amino acids and immunochemical characterization of such conjugates.

  Fu-Tong Liu;Mark Zinnecker;Toshiyuki Hamaoka;David H. Katz

  636
  Citations

• A mechanism underlying synergy between IL-12 and IFN-gamma-inducing factor in enhanced production of IFN-gamma.

  H J Ahn;S Maruo;M Tomura;J Mu

  458
  Citations

• Type II collagen-induced murine arthritis. I. Induction and perpetuation of arthritis require synergy between humoral and cell-mediated immunity.

  N Seki;Y Sudo;T Yoshioka;S Sugihara

  376
  Citations

• Transforming growth factor-beta-induced inhibition of T cell function. Susceptibility difference in T cells of various phenotypes and functions and its relevance to immunosuppression in the tumor-bearing state.

  T. Tada;S. Ohzeki;K. Utsumi;H. Takiuchi

  370
  Citations

• Synergy of IL-12 and IL-18 for IFN-γ Gene Expression: IL-12-Induced STAT4 Contributes to IFN-γ Promoter Activation by Up-Regulating the Binding Activity of IL-18-Induced Activator Protein 1

  Masakiyo Nakahira;Hyun Jong Ahn;Woong Ryeon Park;Ping Gao

  368
  Citations

• Essential role for ERK2 mitogen-activated protein kinase in placental development.

  Naoya Hatano;Yoshiko Mori;Masatsugu Oh‐hora;Atsushi Kosugi

  368
  Citations

• Cell Interactions Between Histoincompatible T and B Lymphocytes. The H-2 Gene Complex Determines Successful Physiologic Lymphocyte Interactions

  David H. Katz;Toshiyuki Hamaoka;Martin E. Dorf;Baruj Benacerraf

  302
  Citations

• A Novel Function of Vα14+CD4+NKT Cells: Stimulation of IL-12 Production by Antigen-Presenting Cells in the Innate Immune System

  Michio Tomura;Wen-Gong Yu;Hyun-Jong Ahn;Motozo Yamashita

  300
  Citations

• Systemic administration of rIL-12 induces complete tumor regression and protective immunity: response is correlated with a striking reversal of suppressed IFN-γ production by anti-tumor T cells

  Jian-Ping Zou;Norihiko Yamamoto;Tetsuya Fujii;Hiroshi Takenaka

  296
  Citations

• Enhanced Induction of Antitumor T-Cell Responses by Cytotoxic T Lymphocyte-associated Molecule-4 Blockade: The Effect Is Manifested Only at the Restricted Tumor-bearing Stages

  Yi Fu Yang;Jian Ping Zou;Jie Mu;Rishani Wijesuriya

  259
  Citations

• CELL INTERACTIONS BETWEEN HISTOINCOMPATIBLE T AND B LYMPHOCYTES : IV. INVOLVEMENT OF THE IMMUNE RESPONSE (Ir) GENE IN THE CONTROL OF LYMPHOCYTE INTERACTIONS IN RESPONSES CONTROLLED BY THE GENE

  David H. Katz;Toshiyuki Hamaoka;Martin E. Dorf;Paul H. Maurer

  241
  Citations

• The role of tumor-specific Lyt-1+2- T cells in eradicating tumor cells in vivo. I. Lyt-1+2- T cells do not necessarily require recruitment of host's cytotoxic T cell precursors for implementation of in vivo immunity.

  H Fujiwara;M Fukuzawa;T Yoshioka;H Nakajima

  221
  Citations

• Non-CD28 costimulatory molecules present in T cell rafts induce T cell costimulation by enhancing the association of TCR with rafts.

  Yumi Yashiro-Ohtani;Xu-Yu Zhou;Kazuhito Toyo-oka;Xu-Guang Tai

  217
  Citations

• Antigen-induced T cell-replacing factor (TRF). III. Establishment of T cell hybrid clone continuously producing TRF and functional analysis of released TRF.

  K Takatsu;K Tanaka;A Tominaga;Y Kumahara

  209
  Citations

• Plasma cholecystokinin responses after ingestion of liquid meal and intraduodenal infusion of fat, amino acids, or hydrochloric acid in man: analysis with region specific radioimmunoassay.

  Himeno S;Tarui S;Kanayama S;Kuroshima T

  204
  Citations

• Administration of Recombinant Interleukin 12 Prevents Outgrowth of Tumor Cells Metastasizing Spontaneously to Lung and Lymph Nodes

  Jie Mu;Jian-Ping Zou;Norihiko Yamamoto;Tateki Tsutsui

  199
  Citations

• A Critical Role for IL-18 in the Proliferation and Activation of NK1.1+CD3− Cells

  Michio Tomura;Xu-Yu Zhou;Seiji Maruo;Hyun-Jong Ahn

  195
  Citations

• Cutting edge: Fyn is essential for tyrosine phosphorylation of Csk-binding protein/phosphoprotein associated with glycolipid-enriched microdomains in lipid rafts in resting T cells.

  Koubun Yasuda;Masakazu Nagafuku;Takaki Shima;Masato Okada

  179
  Citations

• IMMUNOLOGICAL TOLERANCE IN BONE MARROW-DERIVED LYMPHOCYTES I. EVIDENCE FOR AN INTRACELLULAR MECHANISM OF INACTIVATION OF HAPTEN-SPECIFIC PRECURSORS OF ANTIBODY-FORMING CELLS

  David H. Katz;Toshiyuki Hamaoka;Baruj Benacerraf

  174
  Citations