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Biology and Biochemistry

D-Index
56
Citations
11647
World Ranking
14404
National Ranking
6064

Overview

Lyuba Varticovski is a researcher affiliated with the National Institutes of Health in the United States. Their work spans multiple topics within the broad fields of Biochemistry, Genetics and Molecular Biology, and Medicine.

The main research fields addressed include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these fields, Varticovski's subfields of study focus on molecular biology, health, toxicology and mutagenesis, genetics, oncology, and surgery.

  • Molecular Biology
  • Health, Toxicology and Mutagenesis
  • Genetics
  • Oncology
  • Surgery

The topics of their work cover various aspects related to endocrine disruption, hormonal effects, epigenetics, protein regulation, chromatin remodeling, lung cancer research, and reproductive studies.

  • Effects and risks of endocrine disrupting chemicals
  • Estrogen and related hormone effects
  • Epigenetics and DNA Methylation
  • Protein Degradation and Inhibitors
  • Chromatin Remodeling and Cancer
  • Lung Cancer Research Studies
  • Hormonal and reproductive studies

Lyuba Varticovski has published in several academic venues, with the most frequent venues including:

  • Journal of Thoracic Oncology
  • Cancer Research
  • UNC Libraries
  • Molecular and Cellular Endocrinology
  • The Science of The Total Environment

The scientist's frequent coauthors include:

  • Gordon L. Hager
  • Diana A. Stavreva
  • Songjoon Baek
  • Razi Raziuddin
  • David S. Schrump

Among notable publications authored or coauthored by Varticovski are:

  • Endocrine disruptors of sex hormone activities, 2021, Molecular and Cellular Endocrinology
  • Mapping multiple endocrine disrupting activities in Virginia rivers using effect-based assays, 2021, The Science of The Total Environment
  • Genome-Wide Analysis Identifies Nuclear Factor 1C as a Novel Transcription Factor and Potential Therapeutic Target in SCLC, 2024, Journal of Thoracic Oncology
  • Novel biosensor for high-throughput detection of progesterone receptor-interacting endocrine disruptors, 2024, Scientific Reports
  • Bile acids target an exposed cavity in the glucocorticoid receptor modulating receptor self-assembly, chromatin binding and transcriptional activity, 2025, bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • Brca1 breast tumors contain distinct CD44+/CD24- and CD133+ cells with cancer stem cell characteristics

    Mollie H Wright;Anna Maria Calcagno;Crystal D Salcido;Marisa D Carlson

  • The knockout mouse project

    Christopher P. Austin;James F. Battey;Allan Bradley;Maja Bucan

  • Hypoxia Induces Vascular Endothelial Growth Factor in Cultured Human Endothelial Cells

    Atsushi Namiki;Edi Brogi;Marianne Kearney;Elizabeth A. Kim

  • The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane.

    Urmi Bandyopadhyay;Susmita Kaushik;Lyuba Varticovski;Ana Maria Cuervo

  • Hypoxia-induced paracrine regulation of vascular endothelial growth factor receptor expression

    E. Brogi;G. Schatteman;Tiangen Wu;E. A. Kim

  • The colony stimulating factor-1 receptor associates with and activates phosphatidylinositol-3 kinase

    Lyuba Varticovski;Brian Druker;Deborah Morrison;Deborah Morrison;Lewis Cantley

  • Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models

    Eloisi Caldas-Lopes;Leandro Cerchietti;James H. Ahn;Cristina C. Clement

  • Prolonged Drug Selection of Breast Cancer Cells and Enrichment of Cancer Stem Cell Characteristics

    Anna Maria Calcagno;Crystal D. Salcido;Jean Pierre Gillet;Chung Pu Wu

  • Activation of phosphatidylinositol 3-kinase in cells expressing abl oncogene variants.

    Lyuba Varticovski;George Q. Daley;Peter Jackson;David Baltimore

  • Signal Transduction through the EGF Receptor Transfected in IL-3--Dependent Hematopoietic Cells

    JH Pierce;M Ruggiero;TP Fleming;PP Di Fiore

  • Chaperone-mediated autophagy is required for tumor growth

    Maria Kon;Roberta Kiffin;Hiroshi Koga;Javier Chapochnick

  • In Vitro Evidence That Myocardial Ischemia Resulting from 5-Fluorouracil Chemotherapy Is Due to Protein Kinase C-mediated Vasoconstriction of Vascular Smooth Muscle

    Morris Mosseri;Howard J. Fingert;Lyuba Varticovski;Saurabh Chokshi

  • Molecular characterisation of side population cells with cancer stem cell-like characteristics in small-cell lung cancer

    C D Salcido;A Larochelle;B J Taylor;C E Dunbar

  • A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6-dependent B cell lymphomas.

    Leandro C. Cerchietti;Eloisi C. Lopes;Shao Ning Yang;Katerina Hatzi

  • Interleukin-2 receptor regulates activation of phosphatidylinositol 3-kinase

    B Remillard;R Petrillo;W Maslinski;M Tsudo

  • Role of PI 3-kinase in angiopoietin-1-mediated migration and attachment-dependent survival of endothelial cells.

    Koshi Fujikawa;Isabel de Aos Scherpenseel;Suresh K. Jain;Eleonora Presman

  • Phosphatidylinositol 3-kinase and its novel product, phosphatidylinositol 3-phosphate, are present in Saccharomyces cerevisiae.

    K R Auger;C L Carpenter;C L Carpenter;L C Cantley;L Varticovski

  • Divergence in signal transduction pathways of platelet-derived growth factor (PDGF) and epidermal growth factor (EGF) receptors: Involvement of sphingosine 1-phosphate in PDGF but not EGF signaling

    C.S. Sheela Rani;Fang Wang;Elena Fuior;Alvin Berger

  • The role of phosphoinositide 3-kinase in taurocholate-induced trafficking of ATP-dependent canalicular transporters in rat liver

    Suniti Misra;Peter Ujházy;Zenaida Gatmaitan;Lyuba Varticovski

  • Inhibitor of growth 4 suppresses cell spreading and cell migration by interacting with a novel binding partner, liprin alpha1.

    Jiang Cheng Shen;Motoko Unoki;Damien Ythier;Alain Duperray

Frequent Co-Authors

Gordon L. Hager
Gordon L. Hager National Institutes of Health
Stephen D. Hursting
Stephen D. Hursting University of North Carolina at Chapel Hill
Curtis C. Harris
Curtis C. Harris National Institutes of Health
Irwin M. Arias
Irwin M. Arias National Institutes of Health
Xavier Leleu
Xavier Leleu Harvard University
Irene M. Ghobrial
Irene M. Ghobrial Harvard University
Lewis C. Cantley
Lewis C. Cantley Harvard University
Yves Pommier
Yves Pommier National Institutes of Health
Barrett J. Rollins
Barrett J. Rollins Brigham and Women's Hospital
Michael Dean
Michael Dean National Institutes of Health

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