What is he best known for?
The fields of study he is best known for:
- Gene
- Genetics
- Gene expression
The scientist’s investigation covers issues in Schwann cell, Myelin, Cell biology, Neuroscience and Integrin.
His study in the field of Schwann cell proliferation is also linked to topics like ADAM17 Protein.
Lawrence Wrabetz interconnects Molecular biology, Signal transduction, Neuregulin 1 and Transgene in the investigation of issues within Myelin.
Lawrence Wrabetz studies Cell biology, namely Laminin.
His Neuroscience research includes themes of Phenotype and Cellular differentiation.
His Integrin research is multidisciplinary, relying on both Peripheral nervous system, Axon and Cell adhesion molecule.
His most cited work include:
- c-Jun is a negative regulator of myelination (283 citations)
- Conditional disruption of β1 integrin in Schwann cells impedes interactions with axons (279 citations)
- Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit. (247 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Cell biology, Myelin, Schwann cell, Neuroscience and Molecular biology.
Lawrence Wrabetz has researched Cell biology in several fields, including Peripheral nervous system and Immunology.
He has included themes like Endoplasmic reticulum, Biochemistry and Neuregulin 1 in his Myelin study.
His biological study spans a wide range of topics, including Gene expression, Transcription factor, Downregulation and upregulation, Wallerian degeneration and Receptor.
His Neuroscience study combines topics from a wide range of disciplines, such as Cellular differentiation, c-jun and Nociception.
His Molecular biology research is multidisciplinary, incorporating perspectives in Cell culture, Neuroglia, Mutation, Myelin basic protein and Genetically modified mouse.
He most often published in these fields:
- Cell biology (50.29%)
- Myelin (49.12%)
- Schwann cell (34.50%)
What were the highlights of his more recent work (between 2017-2021)?
- Cell biology (50.29%)
- Myelin (49.12%)
- Schwann cell (34.50%)
In recent papers he was focusing on the following fields of study:
Lawrence Wrabetz focuses on Cell biology, Myelin, Schwann cell, Peripheral nervous system and Myelin protein zero.
His studies link Phenotype with Cell biology.
Lawrence Wrabetz combines subjects such as Downregulation and upregulation, Leukodystrophy and Calcineurin with his study of Myelin.
His research in Peripheral nervous system intersects with topics in Myelin maintenance and Integrin.
In his study, Wild type and Axon is strongly linked to Gene silencing, which falls under the umbrella field of Myelin protein zero.
His work in Unfolded protein response tackles topics such as Schwann cell differentiation which are related to areas like Transcription factor, SOX2 and Mutant protein.
Between 2017 and 2021, his most popular works were:
- Consensus guidelines for newborn screening, diagnosis and treatment of infantile Krabbe disease. (24 citations)
- Impairment of protein degradation and proteasome function in hereditary neuropathies (16 citations)
- Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy. (15 citations)
In his most recent research, the most cited papers focused on:
Lawrence Wrabetz mainly focuses on Cell biology, Myelin, Peripheral nervous system, Downregulation and upregulation and Schwann cell.
He is interested in Unfolded protein response, which is a branch of Cell biology.
His studies in Unfolded protein response integrate themes in fields like Phenotype, Myelin maintenance and Schwann cell differentiation.
The various areas that Lawrence Wrabetz examines in his Peripheral nervous system study include Myelin protein zero, Neuregulin 1 and MAPK/ERK pathway.
His MAPK/ERK pathway research is multidisciplinary, incorporating elements of Oligodendrocyte-Myelin Glycoprotein, Sciatic nerve, PI3K/AKT/mTOR pathway and Protein kinase B.
The concepts of his Schwann cell study are interwoven with issues in Cell, Transcription factor, Neurodegeneration, Neuroinflammation and Macrophage.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
