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Biology and Biochemistry

D-Index
59
Citations
10918
World Ranking
12698
National Ranking
5413

Overview

M. Laura Feltri was affiliated with the University at Buffalo, State University of New York in the United States. Their research focused predominantly on the cellular and molecular mechanisms underlying peripheral nervous system development and pathology, with an emphasis on Schwann cells and nerve regeneration.

Their published work includes studies on Schwann cell biology and peripheral nerve regeneration. Key recent papers include:

  • Schwann cell interactions during the development of the peripheral nervous system, 2020, Developmental Neurobiology
  • Beyond Wrapping: Canonical and Noncanonical Functions of Schwann Cells, 2022, Annual Review of Neuroscience
  • YAP and TAZ regulate Schwann cell proliferation and differentiation during peripheral nerve regeneration, 2020, Glia
  • Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction, 2020, Neuron
  • Peripheral glia diversity, 2021, Journal of Anatomy

The scientist frequently collaborated with several coauthors, including Lawrence Wrabetz, Edward Hurley, Yannick Poitelon, Leandro N. Marziali, and Emma R. Wilson. This recurring collaboration reflects a network focused on neural and molecular biology research.

Their work appeared often in specialized scientific venues such as:

  • Glia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Neuroscience
  • Nature Communications
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature

M. Laura Feltri's research contributions prominently spanned several scientific fields, notably Biochemistry, Genetics and Molecular Biology; Neuroscience; and Medicine. Within these broader disciplines, their studies addressed subfields including Cellular and Molecular Neuroscience, Molecular Biology, Cell Biology, Developmental Neuroscience, and Physiology.

The main topics explored in their work encompassed:

  • Hereditary Neurological Disorders
  • Neurogenesis and neuroplasticity mechanisms
  • Nerve injury and regeneration
  • Lysosomal Storage Disorders Research
  • Signaling Pathways in Disease
  • Hippo pathway signaling and YAP/TAZ
  • Endoplasmic Reticulum Stress and Disease

Best Publications

  • c-Jun is a negative regulator of myelination

    DB Parkinson;A Bhaskaran;P Arthur-Farraj;LA Noon

  • Conditional disruption of β1 integrin in Schwann cells impedes interactions with axons

    M. Laura Feltri;Diana Graus Porta;Stefano C. Previtali;Alessandro Nodari

  • Notch controls embryonic Schwann cell differentiation, postnatal myelination and adult plasticity

    Ashwin Woodhoo;Maria B Duran Alonso;Anna Droggiti;Mark Turmaine

  • Signals to promote myelin formation and repair

    Carla Taveggia;Maria Laura Feltri;Lawrence Wrabetz

  • Unique Role of Dystroglycan in Peripheral Nerve Myelination, Nodal Structure, and Sodium Channel Stabilization

    Fumiaki Saito;Steven A Moore;Rita Barresi;Michael D Henry

  • Ablation of the UPR-Mediator CHOP Restores Motor Function and Reduces Demyelination in Charcot-Marie-Tooth 1B Mice

    Maria Pennuto;Elisa Tinelli;MariaChiara Malaguti;Ubaldo Del Carro

  • The Adhesion GPCR GPR126 Has Distinct, Domain-Dependent Functions in Schwann Cell Development Mediated by Interaction with Laminin-211

    Sarah C. Petersen;Rong Luo;Ines Liebscher;Stefanie Giera

  • P0-Cre transgenic mice for inactivation of adhesion molecules in Schwann cells.

    Maria Laura Feltri;Maurizio D'antonio;Stefano Previtali;Marina Fasolini

  • β1 integrin activates Rac1 in Schwann cells to generate radial lamellae during axonal sorting and myelination

    Alessandro Nodari;Desirée Zambroni;Angelo Quattrini;Felipe A. Court

  • Schwann cells expressing dismutase active mutant SOD1 unexpectedly slow disease progression in ALS mice

    Christian S. Lobsiger;Severine Boillee;Melissa McAlonis-Downes;Amir M. Khan

  • Disruption of Mtmr2 produces CMT4B1-like neuropathy with myelin outfolding and impaired spermatogenesis

    Alessandra Bolino;Annalisa Bolis;Stefano Carlo Previtali;Giorgia Dina

  • YAP and TAZ control peripheral myelination and the expression of laminin receptors in Schwann cells

    Yannick Poitelon;Camila Lopez-Anido;Kathleen Catignas;Caterina Berti

  • Schwann Cell-Specific Ablation of Laminin γ1 Causes Apoptosis and Prevents Proliferation

    Wei-Ming Yu;M. Laura Feltri;Lawrence Wrabetz;Sidney Strickland

  • Beta 4 integrin expression in myelinating Schwann cells is polarized, developmentally regulated and axonally dependent

    M.L. Feltri;S.S. Scherer;R. Nemni;J. Kamholz

  • Resetting translational homeostasis restores myelination in Charcot-Marie-Tooth disease type 1B mice.

    Maurizio D’Antonio;Nicolò Musner;Cristina Scapin;Daniela Ungaro

  • Different intracellular pathomechanisms produce diverse Myelin Protein Zero neuropathies in transgenic mice.

    Lawrence Wrabetz;Maurizio D'Antonio;Maria Pennuto;Gabriele Dati

  • P0 glycoprotein overexpression causes congenital hypomyelination of peripheral nerves

    Lawrence Wrabetz;Maria Laura Feltri;Angelo Quattrini;Daniele Imperiale

  • Role of integrins in the peripheral nervous system.

    Stefano C. Previtali;M. Laura Feltri;Juan J. Archelos;Angelo Quattrini

  • TACE (ADAM17) inhibits Schwann cell myelination

    Rosa La Marca;Federica Cerri;Keisuke Horiuchi;Angela Bachi

  • Expression of Laminin Receptors in Schwann Cell Differentiation: Evidence for Distinct Roles

    Stefano C. Previtali;Alessandro Nodari;Carla Taveggia;Celia Pardini

Frequent Co-Authors

Lawrence Wrabetz
Lawrence Wrabetz University at Buffalo, State University of New York
Angelo Quattrini
Angelo Quattrini Vita-Salute San Raffaele University
Michael E. Shy
Michael E. Shy University of Iowa
Albee Messing
Albee Messing University of Wisconsin–Madison
Felipe A. Court
Felipe A. Court Buck Institute for Research on Aging
Steven S. Scherer
Steven S. Scherer University of Pennsylvania
Daniel A. Kirschner
Daniel A. Kirschner Boston College
Kevin P. Campbell
Kevin P. Campbell University of Iowa
John Svaren
John Svaren University of Wisconsin–Madison
Sidney Strickland
Sidney Strickland Rockefeller University

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