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Daniel A. Kirschner

Daniel A. Kirschner

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
17509
World Ranking
9056
National Ranking
4025

Overview

Daniel A. Kirschner is affiliated with Boston College in the United States. Their research spans multiple areas within biochemistry, genetics, molecular biology, pharmacology, toxicology, and pharmaceutics, contributing notably to these intersecting disciplines.

Their specialty fields include:

  • Biochemistry, Genetics and Molecular Biology
  • Pharmacology, Toxicology and Pharmaceutics

They have worked on several subfields, including:

  • Cell Biology
  • Pharmaceutical Science
  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Biochemistry

The main topics covered in their work address:

  • Chemical Reactions and Isotopes
  • Metabolomics and Mass Spectrometry Studies
  • Hereditary Neurological Disorders
  • Cellular transport and secretion
  • Amino Acid Enzymes and Metabolism
  • Caveolin-1 and cellular processes

Daniel A. Kirschner's recent publications reveal an emphasis on biochemical and neurological studies. Notable papers include:

  • "Exploiting Sphingo- and Glycerophospholipid Impairment to Select Effective Drugs and Biomarkers for CMT1A," published in 2020 in Frontiers in Neurology
  • "Metabolically-incorporated deuterium in myelin localized by neutron diffraction and identified by mass spectrometry," published in 2022 in Current Research in Structural Biology
  • "Metabolically-Incorporated Deuterium in Myelin Localized by Neutron Diffraction and Identified by Mass Spectrometry," published in 2021 in bioRxiv (Cold Spring Harbor Laboratory)

The scientist collaborates frequently with other researchers in related fields. Common co-authors include:

  • Anne Baumann
  • Andrew R. Denninger
  • Marek Domin
  • Bruno Demé
  • Davide Visigalli

Their works appear regularly in respected venues such as:

  • Frontiers in Neurology
  • Current Research in Structural Biology
  • bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

    Bruce A. Yankner;Lawrence K. Duffy;Daniel A. Kirschner

  • On the nucleation and growth of amyloid beta-protein fibrils: detection of nuclei and quantitation of rate constants

    Aleksey Lomakin;Doo Soo Chung;George B. Benedek;Daniel A. Kirschner

  • X-ray diffraction from intraneuronal paired helical filaments and extraneuronal amyloid fibers in Alzheimer disease indicates cross-beta conformation

    Daniel A. Kirschner;Carmela Abraham;Dennis J. Selkoe

  • Synthetic peptide homologous to beta protein from Alzheimer disease forms amyloid-like fibrils in vitro.

    Daniel A. Kirschner;Hideyo Inouye;Lawrence K. Duffy;Alison Sinclair

  • Kinetic theory of fibrillogenesis of amyloid β-protein

    Aleksey Lomakin;David B. Teplow;Daniel A. Kirschner;George B. Benedek

  • Mice deficient for the myelin-associated glycoprotein show subtle abnormalities in myelin.

    Dirk Montag;Karl Peter Giese;Udo Bartsch;Rudolf Martini

  • pH-dependent structural transitions of Alzheimer amyloid peptides.

    P. E. Fraser;J. T. Nguyen;Witold K. Surewicz;D. A. Kirschner

  • Constitutively Active Akt Induces Enhanced Myelination in the CNS

    Ana I. Flores;S. Priyadarshini Narayanan;Emily N. Morse;H. Elizabeth Shick

  • Molecular determinants of amyloid deposition in Alzheimer's disease: conformational studies of synthetic beta-protein fragments.

    Kurt Halverson;Paul E. Fraser;Daniel A. Kirschner;Peter T. Lansbury

  • Structure of beta-crystallite assemblies formed by Alzheimer beta-amyloid protein analogues: analysis by x-ray diffraction

    H. Inouye;P.E. Fraser;D.A. Kirschner

  • Fibril formation by primate, rodent, and Dutch-hemorrhagic analogues of Alzheimer amyloid beta-protein.

    Paul E. Fraser;Jack T. Nguyen;Hideyo Inouye;Witold K. Surewicz

  • Structural Analysis of Alzheimer's β(1–40) Amyloid: Protofilament Assembly of Tubular Fibrils

    Sergey B. Malinchik;Hideyo Inouye;Karen E. Szumowski;Daniel A. Kirschner

  • Myelin membrane structure at 10 A resolution.

    D. L. D. Caspar;Daniel A. Kirschner

  • Effects of Sulfate Ions on Alzheimer β/A4 Peptide Assemblies: Implications for Amyloid Fibril‐Proteoglycan Interactions

    Paul E. Fraser;Jack T. Nguyen;David T. Chin;Daniel A. Kirschner

  • Compact myelin exists in the absence of basic protein in the shiverer mutant mouse.

    D. A. Kirschner;D. A. Kirschner;A. L. Ganser;A. L. Ganser

  • The Formation of Straight and Twisted Filaments from Short Tau Peptides

    Warren J. Goux;Lauren Kopplin;Anh D. Nguyen;Kathryn Leak

  • Water diffusion, T2 and compartmentation in frog sciatic nerve

    Sharon Peled;David G. Cory;Stephen A. Raymond;Daniel A. Kirschner

  • X-ray diffraction of scrapie prion rods and PrP peptides.

    Jack T. Nguyen;Hideyo Inouye;Michael A. Baldwin;Robert J. Fletterick

  • Conformation and fibrillogenesis of Alzheimer Aβ peptides with selected substitution of charged residues

    P.E. Fraser;D.R. McLachlan;W.K. Surewicz;C.A. Mizzen

  • α1‐Antichymotrypsin Binding to Alzheimer Aβ Peptides Is Sequence Specific and Induces Fibril Disaggregation In Vitro

    Paul E. Fraser;Jack T. Nguyen;Donald R. McLachlan;Carmela R. Abraham

Frequent Co-Authors

Paul E. Fraser
Paul E. Fraser University of Toronto
Donald L.D. Caspar
Donald L.D. Caspar Florida State University
David B. Teplow
David B. Teplow University of California, Los Angeles
Mario Salmona
Mario Salmona Mario Negri Institute for Pharmacological Research
Catherine E. Costello
Catherine E. Costello Boston University
Lawrence Wrabetz
Lawrence Wrabetz University at Buffalo, State University of New York
Dennis J. Selkoe
Dennis J. Selkoe Brigham and Women's Hospital
M. Laura Feltri
M. Laura Feltri University at Buffalo, State University of New York
Eliezer Masliah
Eliezer Masliah National Institutes of Health
Edward Rockenstein
Edward Rockenstein University of California, San Diego

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